Phase Ib Gene Editing Trials Market Size, Share, and Trends 2025 to 2034

Phase Ib gene editing trials market advancing with novel in vivo CRISPR therapies like Verve 101, NTLA 2001 and PBGENE HBV in early testing. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : July 2025  |  Report Code : 6443  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Phase Ib Gene Editing Trials Market 

5.1. COVID-19 Landscape: Phase Ib Gene Editing Trials Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Phase Ib Gene Editing Trials Market, By  Gene Editing Platform

8.1. Phase Ib Gene Editing Trials Market, by  Gene Editing Platform

8.1.1. CRISPR/Cas Systems (e.g., Cas9, Cas12, Cas13)

8.1.1.1. Market Revenue and Forecast

8.1.2. Zinc Finger Nucleases (ZFNs)

8.1.2.1. Market Revenue and Forecast

8.1.3. TALENs (Transcription Activator-Like Effector Nucleases)

8.1.3.1. Market Revenue and Forecast

8.1.4. Meganucleases

8.1.4.1. Market Revenue and Forecast

8.1.5. Base & Prime Editors

8.1.5.1. Market Revenue and Forecast

Chapter 9. Global Phase Ib Gene Editing Trials Market, By Therapy Type

9.1. Phase Ib Gene Editing Trials Market, by Therapy Type

9.1.1. In Vivo Gene Editing Therapies

9.1.1.1. Market Revenue and Forecast

9.1.2. Ex Vivo Gene Editing Therapies

9.1.2.1. Market Revenue and Forecast

Chapter 10. Global Phase Ib Gene Editing Trials Market, By Disease Area 

10.1. Phase Ib Gene Editing Trials Market, by Disease Area

10.1.1. Oncology (e.g., gene-edited T-cell therapies)       

10.1.1.1. Market Revenue and Forecast

10.1.2. Rare Genetic Disorders

10.1.2.1. Market Revenue and Forecast

10.1.3. Hematological Disorders (e.g., sickle cell, beta-thalassemia)

10.1.3.1. Market Revenue and Forecast

10.1.4. Ophthalmology

10.1.4.1. Market Revenue and Forecast

10.1.5. Infectious Diseases

10.1.5.1. Market Revenue and Forecast

10.1.6. Neurology

10.1.6.1. Market Revenue and Forecast

10.1.7. Cardiovascular Disorders

10.1.7.1. Market Revenue and Forecast

Chapter 11. Global Phase Ib Gene Editing Trials Market, By Delivery Method

11.1. Phase Ib Gene Editing Trials Market, by Delivery Method

11.1.1. Lipid Nanoparticles (LNPs)

11.1.1.1. Market Revenue and Forecast

11.1.2. Electroporation

11.1.2.1. Market Revenue and Forecast

11.1.3. Viral Vectors

11.1.3.1. Market Revenue and Forecast

11.1.4. Non-Viral Vectors

11.1.4.1. Market Revenue and Forecast

Chapter 12. Global Phase Ib Gene Editing Trials Market, By Trial Sponsor Type

12.1. Phase Ib Gene Editing Trials Market, by Trial Sponsor Type

12.1.1. Biotech/Pharma Companies

12.1.1.1. Market Revenue and Forecast

12.1.2. Academic Institutions

12.1.2.1. Market Revenue and Forecast

12.1.3. Non-Profit Research Organizations

12.1.3.1. Market Revenue and Forecast

12.1.4. Public-Private Collaborations

12.1.4.1. Market Revenue and Forecast

Chapter 13. Global Phase Ib Gene Editing Trials Market, Regional Estimates and Trend Forecast

13.1. North America

13.1.1. Market Revenue and Forecast, by  Gene Editing Platform

13.1.2. Market Revenue and Forecast, by Therapy Type

13.1.3. Market Revenue and Forecast, by Disease Area

13.1.4. Market Revenue and Forecast, by Delivery Method

13.1.5. Market Revenue and Forecast, by Trial Sponsor Type

13.1.6. U.S.

13.1.6.1. Market Revenue and Forecast, by  Gene Editing Platform

13.1.6.2. Market Revenue and Forecast, by Therapy Type

13.1.6.3. Market Revenue and Forecast, by Disease Area

13.1.6.4. Market Revenue and Forecast, by Delivery Method

13.1.6.5. Market Revenue and Forecast, by Trial Sponsor Type  

13.1.7. Rest of North America

13.1.7.1. Market Revenue and Forecast, by  Gene Editing Platform

13.1.7.2. Market Revenue and Forecast, by Therapy Type

13.1.7.3. Market Revenue and Forecast, by Disease Area

13.1.7.4. Market Revenue and Forecast, by Delivery Method

13.1.7.5. Market Revenue and Forecast, by Trial Sponsor Type

13.2. Europe

13.2.1. Market Revenue and Forecast, by  Gene Editing Platform

13.2.2. Market Revenue and Forecast, by Therapy Type

13.2.3. Market Revenue and Forecast, by Disease Area

13.2.4. Market Revenue and Forecast, by Delivery Method  

13.2.5. Market Revenue and Forecast, by Trial Sponsor Type  

13.2.6. UK

13.2.6.1. Market Revenue and Forecast, by  Gene Editing Platform

13.2.6.2. Market Revenue and Forecast, by Therapy Type

13.2.6.3. Market Revenue and Forecast, by Disease Area

13.2.7. Market Revenue and Forecast, by Delivery Method  

13.2.8. Market Revenue and Forecast, by Trial Sponsor Type  

13.2.9. Germany

13.2.9.1. Market Revenue and Forecast, by  Gene Editing Platform

13.2.9.2. Market Revenue and Forecast, by Therapy Type

13.2.9.3. Market Revenue and Forecast, by Disease Area

13.2.10. Market Revenue and Forecast, by Delivery Method

13.2.11. Market Revenue and Forecast, by Trial Sponsor Type

13.2.12. France

13.2.12.1. Market Revenue and Forecast, by  Gene Editing Platform

13.2.12.2. Market Revenue and Forecast, by Therapy Type

13.2.12.3. Market Revenue and Forecast, by Disease Area

13.2.12.4. Market Revenue and Forecast, by Delivery Method

13.2.13. Market Revenue and Forecast, by Trial Sponsor Type

13.2.14. Rest of Europe

13.2.14.1. Market Revenue and Forecast, by  Gene Editing Platform

13.2.14.2. Market Revenue and Forecast, by Therapy Type

13.2.14.3. Market Revenue and Forecast, by Disease Area

13.2.14.4. Market Revenue and Forecast, by Delivery Method

13.2.15. Market Revenue and Forecast, by Trial Sponsor Type

13.3. APAC

13.3.1. Market Revenue and Forecast, by  Gene Editing Platform

13.3.2. Market Revenue and Forecast, by Therapy Type

13.3.3. Market Revenue and Forecast, by Disease Area

13.3.4. Market Revenue and Forecast, by Delivery Method

13.3.5. Market Revenue and Forecast, by Trial Sponsor Type

13.3.6. India

13.3.6.1. Market Revenue and Forecast, by  Gene Editing Platform

13.3.6.2. Market Revenue and Forecast, by Therapy Type

13.3.6.3. Market Revenue and Forecast, by Disease Area

13.3.6.4. Market Revenue and Forecast, by Delivery Method

13.3.7. Market Revenue and Forecast, by Trial Sponsor Type

13.3.8. China

13.3.8.1. Market Revenue and Forecast, by  Gene Editing Platform

13.3.8.2. Market Revenue and Forecast, by Therapy Type

13.3.8.3. Market Revenue and Forecast, by Disease Area

13.3.8.4. Market Revenue and Forecast, by Delivery Method

13.3.9. Market Revenue and Forecast, by Trial Sponsor Type

13.3.10. Japan

13.3.10.1. Market Revenue and Forecast, by  Gene Editing Platform

13.3.10.2. Market Revenue and Forecast, by Therapy Type

13.3.10.3. Market Revenue and Forecast, by Disease Area

13.3.10.4. Market Revenue and Forecast, by Delivery Method

13.3.10.5. Market Revenue and Forecast, by Trial Sponsor Type

13.3.11. Rest of APAC

13.3.11.1. Market Revenue and Forecast, by  Gene Editing Platform

13.3.11.2. Market Revenue and Forecast, by Therapy Type

13.3.11.3. Market Revenue and Forecast, by Disease Area

13.3.11.4. Market Revenue and Forecast, by Delivery Method

13.3.11.5. Market Revenue and Forecast, by Trial Sponsor Type

13.4. MEA

13.4.1. Market Revenue and Forecast, by  Gene Editing Platform

13.4.2. Market Revenue and Forecast, by Therapy Type

13.4.3. Market Revenue and Forecast, by Disease Area

13.4.4. Market Revenue and Forecast, by Delivery Method

13.4.5. Market Revenue and Forecast, by Trial Sponsor Type

13.4.6. GCC

13.4.6.1. Market Revenue and Forecast, by  Gene Editing Platform

13.4.6.2. Market Revenue and Forecast, by Therapy Type

13.4.6.3. Market Revenue and Forecast, by Disease Area

13.4.6.4. Market Revenue and Forecast, by Delivery Method

13.4.7. Market Revenue and Forecast, by Trial Sponsor Type

13.4.8. North Africa

13.4.8.1. Market Revenue and Forecast, by  Gene Editing Platform

13.4.8.2. Market Revenue and Forecast, by Therapy Type

13.4.8.3. Market Revenue and Forecast, by Disease Area

13.4.8.4. Market Revenue and Forecast, by Delivery Method

13.4.9. Market Revenue and Forecast, by Trial Sponsor Type

13.4.10. South Africa

13.4.10.1. Market Revenue and Forecast, by  Gene Editing Platform

13.4.10.2. Market Revenue and Forecast, by Therapy Type

13.4.10.3. Market Revenue and Forecast, by Disease Area

13.4.10.4. Market Revenue and Forecast, by Delivery Method

13.4.10.5. Market Revenue and Forecast, by Trial Sponsor Type

13.4.11. Rest of MEA

13.4.11.1. Market Revenue and Forecast, by  Gene Editing Platform

13.4.11.2. Market Revenue and Forecast, by Therapy Type

13.4.11.3. Market Revenue and Forecast, by Disease Area

13.4.11.4. Market Revenue and Forecast, by Delivery Method

13.4.11.5. Market Revenue and Forecast, by Trial Sponsor Type

13.5. Latin America

13.5.1. Market Revenue and Forecast, by  Gene Editing Platform

13.5.2. Market Revenue and Forecast, by Therapy Type

13.5.3. Market Revenue and Forecast, by Disease Area

13.5.4. Market Revenue and Forecast, by Delivery Method

13.5.5. Market Revenue and Forecast, by Trial Sponsor Type

13.5.6. Brazil

13.5.6.1. Market Revenue and Forecast, by  Gene Editing Platform

13.5.6.2. Market Revenue and Forecast, by Therapy Type

13.5.6.3. Market Revenue and Forecast, by Disease Area

13.5.6.4. Market Revenue and Forecast, by Delivery Method

13.5.7. Market Revenue and Forecast, by Trial Sponsor Type

13.5.8. Rest of LATAM

13.5.8.1. Market Revenue and Forecast, by  Gene Editing Platform

13.5.8.2. Market Revenue and Forecast, by Therapy Type

13.5.8.3. Market Revenue and Forecast, by Disease Area

13.5.8.4. Market Revenue and Forecast, by Delivery Method

13.5.8.5. Market Revenue and Forecast, by Trial Sponsor Type

Chapter 14. Company Profiles

14.1. Caribou Biosciences

14.1.1. Company Overview

14.1.2. Product Offerings

14.1.3. Financial Performance

14.1.4. Recent Initiatives

14.2. Cellectis

14.2.1. Company Overview

14.2.2. Product Offerings

14.2.3. Financial Performance

14.2.4. Recent Initiatives

14.3. Intellia Therapeutics

14.3.1. Company Overview

14.3.2. Product Offerings

14.3.3. Financial Performance

14.3.4. Recent Initiatives

14.4. LogicBio Therapeutics

14.4.1. Company Overview

14.4.2. Product Offerings

14.4.3. Financial Performance

14.4.4. Recent Initiatives

14.5. Poseida Therapeutics

14.5.1. Company Overview

14.5.2. Product Offerings

14.5.3. Financial Performance

14.5.4. Recent Initiatives

14.6. Precision BioSciences

14.6.1. Company Overview

14.6.2. Product Offerings

14.6.3. Financial Performance

14.6.4. Recent Initiatives

14.7. Regenxbio

14.7.1. Company Overview

14.7.2. Product Offerings

14.7.3. Financial Performance

14.7.4. Recent Initiatives

14.8. Sana Biotechnology

14.8.1. Company Overview

14.8.2. Product Offerings

14.8.3. Financial Performance

14.8.4. Recent Initiatives

14.9. Sangamo Therapeutics

14.9.1. Company Overview

14.9.2. Product Offerings

14.9.3. Financial Performance

14.9.4. Recent Initiatives

14.10. Tessera Therapeutics

14.10.1. Company Overview

14.10.2. Product Offerings

14.10.3. Financial Performance

14.10.4. Recent Initiatives

Chapter 15. Research Methodology

15.1. Primary Research

15.2. Secondary Research

15.3. Assumptions

Chapter 16. Appendix

16.1. About Us

16.2. Glossary of Terms

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Frequently Asked Questions

The major players in the phase Ib gene editing trials market include Allogene Therapeutics, Beam Therapeutics, Caribou Biosciences, Cellectis, CRISPR Therapeutics, EdiGene, Editas Medicine, Excision BioTherapeutics, Graphite Bio, iECURE, Intellia Therapeutics, LogicBio Therapeutics, Metagenomi, Poseida Therapeutics, Precision BioSciences, Regenxbio, Sana Biotechnology, Sangamo Therapeutics, Tessera Therapeutics, and Verve Therapeutics.

The driving factors of the phase Ib gene editing trials market are the growing unmet clinical needs in treating rare monogenic disorders are fuelling the development of early-stage gene editing programs.

North America region will lead the global phase Ib gene editing trials market during the forecast period 2025 to 2034.

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