Merz Aesthetics ® Announces EU Approval of Two New Indications for Their Hyaluronic Acid Filler BELOTERO ® Balance
Published: 15 Apr 2026
Author: Towards Healthcare
Merz Aesthetics, the world’s largest dedicated medical aesthetics business, is pleased to announce that BELOTERO® Balance has received EU approval for two additional indications: the treatment of infraorbital hollow and horizontal forehead lines.
BELOTERO Balance is now approved in the EU for the treatment of Infraorbital Hollow and Horizontal Forehead Lines. These two new indications offer additional treatment options and new opportunities to meet patients’ evolving aesthetic needs. It is designed to integrate seamlessly within the skin and deliver predictable, harmonious aesthetic outcomes.
According to Towards Healthcare, the Calcium Hydroxylapatite fillers market is projected to experience significant growth, with estimates suggesting the market size will increase from USD 1.8 billion in 2026 to approximately USD 3.55 billion by 2035, representing a compound annual growth rate (CAGR) of 7.82% from 2026 to 2035. Growth is driven by the increasing popularity of aesthetic treatment with technological advancement to enhance efficacy and safety, to boost the market. It broadens the scope of applications by utilising Calcium Hydroxylapatite in orthopaedic and dental procedures due to its excellent biocompatibility and osteoconductive properties.
About BELOTERO Balance:
It is a hyaluronic acid injectable intended for the filling of facial wrinkles and folds as well as for volume enhancement. It is indicated for injection into the superficial to mid dermis for the treatment of nasolabial folds, marionette lines, perioral lines, horizontal forehead lines, and oral commissures, and into the supraperiosteal plane for the enhancement of the infraorbital hollow, including tear troughs. It is also indicated for submucosal or subcutaneous injection for lip enhancement.
About the BELOTERO Collection:
It is a thoughtfully designed, comprehensive range of highly cohesive hyaluronic acid fillers, developed to deliver predictable, harmonious results through seamless tissue integration. It also offers tailored solutions to enhance facial features, improve skin quality, and visibly reduce signs of ageing, all with long-lasting, natural-looking outcomes.
About Merz Aesthetics
Merz Aesthetics is a medical aesthetics business focusing on empowering healthcare professionals, patients and employees to live every day with confidence. It aims to help people around the world look, feel and live like the best versions of themselves. Clinically proven, its product portfolio includes injectables, devices and skin care treatments designed to meet each patient’s needs with high standards of safety and efficacy.
A recent report by Towards Healthcare highlights that the Calcium Hydroxylapatite fillers market is witnessing growth due to increasing demand for non-surgical aesthetic procedures, consumers are seeking treatments that offer immediate and natural-looking results with minimal downtime, and calcium hydroxylapatite fillers meet these needs by providing long-lasting enhancements in facial aesthetics.
North America currently dominates the market due to high consumer awareness, favourable reimbursement policies, and a well-established network of aesthetic clinics and dermatology centres. The Asia-Pacific region is recognised as the fastest-growing market for Calcium Hydroxylapatite fillers, driven by rising healthcare expenditures, a growing middle-class population, and increasing acceptance of cosmetic procedures.