Small Molecule API Market Size To Rake USD 293.56 Bn By 2030

Published Date : 12 Jun 2023

The global small molecule API market size exceeded USD 189.7 billion in 2022 and is projected to rake USD 293.56 billion by 2030, expanding at a CAGR of 5.61% during the forecast period from 2022 to 2030.

Small Molecule API Market Size and Growth Rate From 2022 To 2030

The rapid acceptance and acquisition of the newly developed technologies with enhance the effectivity of the small molecule API with increased results and integration of small molecule API with other excipients for enhancing the effects of the small molecule API in various disorders. Increased developments of the drug with new small molecule API. 

A small molecule with active pharmaceutical ingredient with low molecular weight of the compound and increased efficiency of the compound strives the market of small molecule with the acquisition of small molecule in pharmaceutical industries and increase in demand for smaller molecule API. Increasing the number of chronic disorders which led to the increasing number of medications with new small molecule API with improved results. Increased government support for developing smaller molecule API with increased government funding with developing infrastructure drives the market to grow during the forecast period.

The outbreak of covid-19 with equal effect with positive and negative effects on the market with stringent rules and regulations imposed decreasing the market share. Post-pandemic with increased research for the development of vaccines which helps to boost the market of small molecule API.

Report Highlights:

  • By type, the synthetics process to be the largest market revenue share with an increase in research and development utilization of small molecule as the raw material during the process of drug development enhances innovations with new features and efficiency which helps to drive the market growth with an increase in the utilization of raw material for drug development.
  • By manufacturer type, the In-house segment with the largest market growth with increased utilization of raw materials for the processing of new drugs with small molecule dependence on the raw material strives the market size of small molecules with rising demands.
  • By the therapeutic sector, cardiovascular disorders with increasing diseases among the population with increasing modern lifestyle and changing dietary intake affect the health of the people, oncology also with highest market share with the increasing number of patients with cancer disorder and an increase in demands from the medical sector for increasing the medications.
  • By applications, hospitals at the highest position with high market share and increasing requirements for new medications.
  • By geography, North America with highest market revenue share and enhance developments introduced by the market players in the small molecule. Asia Pacific also contributes to increasing the market of small molecule API.

Small Molecule API Market Report Scope:

Report Coverage Details
Market Revenue in 2023 USD 200.34 Billion
Projected Forecast Revenue in 2030 USD 293.56 Billion
Growth Rate from 2022 to 2030 CAGR of 5.61%
Largest Market North America
Base Year 2022
Forecast Period 2022 To 2030
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

Regional Snapshots:

Enhance the development of small molecule API across various regions. North America to be the highest market share with an increased number of advance developments in small molecule API with improved efficiency of the small molecule API and enhance number of drug developments in small molecule API with an increasing number of disorders with increased requirements from the pharmaceutical sector and medical sector for developing the drug.

Enhancing the number of facilities in for developing the new drug with continuous research and development for new drug developments with the active pharmaceutical ingredient an organic compound processed synthetically or biologically with reduced cost of the treatment and medication with increased generic medications drives the market to enhance. Asia Pacific region is also in the process with new drug developments with the small molecule API which helps to expand the market to grow. Latin America, the Middle East, and Africa, Europe propel the market growth during the forecast period.

Market Dynamics:


The advance developed small molecule API with increased new drug developments in the market by the key market players with high-efficiency act as the driving force for increasing the market growth of small molecule API. The existence of a number of drugs with small molecule API available in the market with improved results also strives to drive the growth of the market development.

An increasing number of chronic disorders among the people with increased cardiovascular and oncology disorders with an increasing number of patients and increased requirements from the medical sector for improving the patients health. Enhance research and development for new drug developments with increased efficiency and discovery of the new drug molecule and fulfill the demands of the market with rising requirements from the pharmaceutical industry for further process.


A major factor that can restrain the market growth of small molecule API market with the existence of several small molecules with higher efficiency and the number of several options available can hamper the market growth value of small molecule API.  Lack of awareness regarding new developments in underdeveloped regions and various new options available may affect the market size of small molecules. An increased number of key market players also act as the restraining factor in small molecule API.


Increased government support and enhanced providence support for increasing the research and developing the new innovative drug developments from the small molecule API with the enhanced effect of the drug and increasing number of policies such as reimbursement which help to access the benefits of new treatment for common people. This helps to strive the market of small molecules to grow at a larger extent with increased demands from the pharmaceutical industry and medical sector for new drug developments. Increased research and development from the key market players. A large amount of funding is invested by the key market players for increasing the research of small molecule API with increased utilization from the pharmaceutical sectors and enhancing benefits to enlarge the market of small molecule API.


Numerous key market players with an increased number of options available with improved efficacy of the small molecule API may challenge the market development with an increased revenue share of small molecule API. Lack of skill among the people for the development of the new small molecule with innovative features may affect the growth rate of small molecule API. Imposition of rules and regulations regarding the utilization and handling of the small molecule API with the correct amount of small molecules added up with the excipients for increasing the efficiency of large amounts of small molecules may affect the health of the individuals with the development of adverse drug reactions and handling of the small molecule with hazardous effects of a particular drug may challenge the market growth.

Recent Developments:

  • March 2021, Oral administration of the developed molecule such as Gefaoixant for refractory type of cough introduced for adults and approval by U.S. Food and Drug Administration.
  • March 2022, Sumitomo Chemical Co., Ltd introduced the smal molecule API with all the requirements and developed manufacturing unit in Japan.

Major Key Players:

  • Gilead Sciences, Inc
  • Johnson Matthey
  • Teva Pharmaceutical Industries Ltd
  • Sun Pharmaceutical Industries Ltd
  • Siegfried Holding AG
  • Pfizer
  • Novartis AG
  • Merck KGaA
  • Lonza, GSk plc
  • Dr. Reddy's Laboratories Ltd
  • Cambrex Corporation
  • Allergan
  • Albemarle Corporation
  • Hoffmann-La Roche Ltd
  • AstraZeneca
  • Albany Molecular Research Inc.
  • Sanofi S.A
  • Baxter International Inc
  • Celgene Corporation
  • Boehringer Ingelheim International GmbH

Market Segmentation:

By Type

  • Synthetic
  • Biological

By Manufacturer

  • In-house
  • Outsourced

By Application

  • Clinical
  • Commercial

By Therapeutic Sector

  • Cardiovascular 
  • Oncology
  • CNS and Neurology
  • Pulmonology
  • Endocrinology
  • Gastroentrology
  • Nephrology
  • Orthopedic 
  • Gynecological 
  • Opthalmic 
  • Dermatology
  • Urology
  • Immunology
  • Respiratory disorders
  • Cosmetic and plastic 
  • General surgery
  • Others

By Application

  • Hospitals
  • Ambulatory Surgical Center
  • Health clinics
  • Others

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