Oncology Combination Therapy Market Size, Share, and Trends 2025 to 2034

The oncology combination therapy market is expanding due to growing cancer incidence, improved survival rates with synergistic drug combinations, and ongoing innovations in immunotherapy and targeted treatments. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : July 2025  |  Report Code : 6371  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on  Oncology Combination Therapy Market 

5.1. COVID-19 Landscape:  Oncology Combination Therapy Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Oncology Combination Therapy Market, By Therapy Type

8.1.  Oncology Combination Therapy Market, by Therapy Type

8.1.1. Chemotherapy + Targeted Therapy

8.1.1.1. Market Revenue and Forecast  

8.1.2. Immunotherapy + Chemotherapy

8.1.2.1. Market Revenue and Forecast  

8.1.3. Immunotherapy + Targeted Therapy

8.1.3.1. Market Revenue and Forecast  

8.1.4. Dual Immunotherapy (PD-1 + CTLA-4, etc.)

8.1.4.1. Market Revenue and Forecast  

8.1.5. Radiation + Systemic Therapies

8.1.5.1. Market Revenue and Forecast

8.1.6. Hormonal + Targeted Therapy

8.1.6.1. Market Revenue and Forecast    

Chapter 9. Global Oncology Combination Therapy Market, By Drug Class Combination

9.1.  Oncology Combination Therapy Market, by Drug Class Combination

9.1.1. Small Molecules + Monoclonal Antibodies

9.1.1.1. Market Revenue and Forecast  

9.1.2. Checkpoint Inhibitors + Kinase Inhibitors

9.1.2.1. Market Revenue and Forecast  

9.1.3. Cytotoxics + Immune Modulators

9.1.3.1. Market Revenue and Forecast  

9.1.4. Antibody-Drug Conjugates + Chemotherapy

9.1.4.1. Market Revenue and Forecast  

9.1.5. Cell Therapy + Checkpoint Inhibitors

9.1.5.1. Market Revenue and Forecast  

Chapter 10. Global Oncology Combination Therapy Market, By Cancer Type

10.1.  Oncology Combination Therapy Market, by Cancer Type

10.1.1. Non-Small Cell Lung Cancer (NSCLC)

10.1.1.1. Market Revenue and Forecast  

10.1.2. Triple-Negative Breast Cancer (TNBC)

10.1.2.1. Market Revenue and Forecast  

10.1.3. Colorectal Cancer

10.1.3.1. Market Revenue and Forecast  

10.1.4. Melanoma

10.1.4.1. Market Revenue and Forecast  

10.1.5. Blood Cancers (Lymphoma, Leukemia)

10.1.5.1. Market Revenue and Forecast  

10.1.5. Prostate and Bladder Cancers

10.1.5.1. Market Revenue and Forecast  

Chapter 11. Global Oncology Combination Therapy Market, By Route of Administration

11.1.  Oncology Combination Therapy Market, by Route of Administration

11.1.1. Intravenous (IV)

11.1.1.1. Market Revenue and Forecast  

11.1.2. Oral

11.1.2.1. Market Revenue and Forecast  

11.1.3. Subcutaneous (SC)

11.1.3.1. Market Revenue and Forecast  

11.1.4. Intratumoral

11.1.4.1. Market Revenue and Forecast  

Chapter 12. Global Oncology Combination Therapy Market, By Treatment Intent

12.1.  Oncology Combination Therapy Market, by Treatment Intent

12.1.1. First-Line Therapy

12.1.1.1. Market Revenue and Forecast  

12.1.2. Second-Line and Salvage Therapy

12.1.2.1. Market Revenue and Forecast  

12.1.3. Neoadjuvant and Adjuvant Therapy

12.1.3.1. Market Revenue and Forecast  

12.1.4. Maintenance Therapy

12.1.4.1. Market Revenue and Forecast  

Chapter 13. Global Oncology Combination Therapy Market, By End-User

13.1.  Oncology Combination Therapy Market, by End-User

13.1.1. Specialty Cancer Hospitals

13.1.1.1. Market Revenue and Forecast  

13.1.2. Academic & Research Institutions

13.1.2.1. Market Revenue and Forecast  

13.1.3. Outpatient Oncology Clinics

13.1.3.1. Market Revenue and Forecast  

13.1.4. Homecare (limited to oral combinations)

13.1.4.1. Market Revenue and Forecast  

Chapter 14. Global Oncology Combination Therapy Market, Regional Estimates and Trend Forecast

14.1. North America

14.1.1. Market Revenue and Forecast, by Therapy Type  

14.1.2. Market Revenue and Forecast, by Drug Class Combination  

14.1.3. Market Revenue and Forecast, by Cancer Type  

14.1.4. Market Revenue and Forecast, by Route of Administration  

14.1.5. Market Revenue and Forecast, by Treatment Intent  

14.1.6. Market Revenue and Forecast, by End-User  

14.1.7. U.S.

14.1.7.1. Market Revenue and Forecast, by Therapy Type  

14.1.7.2. Market Revenue and Forecast, by Drug Class Combination  

14.1.7.3. Market Revenue and Forecast, by Cancer Type  

14.1.7.4. Market Revenue and Forecast, by Route of Administration  

14.1.8. Market Revenue and Forecast, by Treatment Intent  

14.1.8.1. Market Revenue and Forecast, by End-User   

14.1.9. Rest of North America

14.1.9.1. Market Revenue and Forecast, by Therapy Type  

14.1.9.2. Market Revenue and Forecast, by Drug Class Combination  

14.1.9.3. Market Revenue and Forecast, by Cancer Type  

14.1.9.4. Market Revenue and Forecast, by Route of Administration  

14.1.10. Market Revenue and Forecast, by Treatment Intent  

14.1.11. Market Revenue and Forecast, by End-User  

14.1.11.1.

14.2. Europe

14.2.1. Market Revenue and Forecast, by Therapy Type  

14.2.2. Market Revenue and Forecast, by Drug Class Combination  

14.2.3. Market Revenue and Forecast, by Cancer Type  

14.2.4. Market Revenue and Forecast, by Route of Administration   

14.2.5. Market Revenue and Forecast, by Treatment Intent  

14.2.6. Market Revenue and Forecast, by End-User  

14.2.7.

14.2.8. UK

14.2.8.1. Market Revenue and Forecast, by Therapy Type  

14.2.8.2. Market Revenue and Forecast, by Drug Class Combination  

14.2.8.3. Market Revenue and Forecast, by Cancer Type  

14.2.9. Market Revenue and Forecast, by Route of Administration   

14.2.10. Market Revenue and Forecast, by Treatment Intent  

14.2.10.1. Market Revenue and Forecast, by End-User   

14.2.11. Germany

14.2.11.1. Market Revenue and Forecast, by Therapy Type  

14.2.11.2. Market Revenue and Forecast, by Drug Class Combination  

14.2.11.3. Market Revenue and Forecast, by Cancer Type  

14.2.12. Market Revenue and Forecast, by Route of Administration  

14.2.13. Market Revenue and Forecast, by Treatment Intent  

14.2.14. Market Revenue and Forecast, by End-User  

14.2.14.1.

14.2.15. France

14.2.15.1. Market Revenue and Forecast, by Therapy Type  

14.2.15.2. Market Revenue and Forecast, by Drug Class Combination  

14.2.15.3. Market Revenue and Forecast, by Cancer Type  

14.2.15.4. Market Revenue and Forecast, by Route of Administration  

14.2.16. Market Revenue and Forecast, by Treatment Intent  

14.2.16.1. Market Revenue and Forecast, by End-User  

14.2.17. Rest of Europe

14.2.17.1. Market Revenue and Forecast, by Therapy Type  

14.2.17.2. Market Revenue and Forecast, by Drug Class Combination  

14.2.17.3. Market Revenue and Forecast, by Cancer Type  

14.2.17.4. Market Revenue and Forecast, by Route of Administration  

14.2.18. Market Revenue and Forecast, by Treatment Intent  

14.2.18.1. Market Revenue and Forecast, by End-User  

14.3. APAC

14.3.1. Market Revenue and Forecast, by Therapy Type  

14.3.2. Market Revenue and Forecast, by Drug Class Combination  

14.3.3. Market Revenue and Forecast, by Cancer Type  

14.3.4. Market Revenue and Forecast, by Route of Administration  

14.3.5. Market Revenue and Forecast, by Treatment Intent  

14.3.6. Market Revenue and Forecast, by End-User  

14.3.7. India

14.3.7.1. Market Revenue and Forecast, by Therapy Type  

14.3.7.2. Market Revenue and Forecast, by Drug Class Combination  

14.3.7.3. Market Revenue and Forecast, by Cancer Type  

14.3.7.4. Market Revenue and Forecast, by Route of Administration  

14.3.8. Market Revenue and Forecast, by Treatment Intent  

14.3.9. Market Revenue and Forecast, by End-User  

14.3.10. China

14.3.10.1. Market Revenue and Forecast, by Therapy Type  

14.3.10.2. Market Revenue and Forecast, by Drug Class Combination  

14.3.10.3. Market Revenue and Forecast, by Cancer Type  

14.3.10.4. Market Revenue and Forecast, by Route of Administration  

14.3.11. Market Revenue and Forecast, by Treatment Intent  

14.3.11.1. Market Revenue and Forecast, by End-User  

14.3.12. Japan

14.3.12.1. Market Revenue and Forecast, by Therapy Type  

14.3.12.2. Market Revenue and Forecast, by Drug Class Combination  

14.3.12.3. Market Revenue and Forecast, by Cancer Type  

14.3.12.4. Market Revenue and Forecast, by Route of Administration  

14.3.12.5. Market Revenue and Forecast, by Treatment Intent  

14.3.12.6. Market Revenue and Forecast, by End-User  

14.3.13. Rest of APAC

14.3.13.1. Market Revenue and Forecast, by Therapy Type  

14.3.13.2. Market Revenue and Forecast, by Drug Class Combination  

14.3.13.3. Market Revenue and Forecast, by Cancer Type  

14.3.13.4. Market Revenue and Forecast, by Route of Administration  

14.3.13.5. Market Revenue and Forecast, by Treatment Intent  

14.3.13.6. Market Revenue and Forecast, by End-User  

14.4. MEA

14.4.1. Market Revenue and Forecast, by Therapy Type  

14.4.2. Market Revenue and Forecast, by Drug Class Combination  

14.4.3. Market Revenue and Forecast, by Cancer Type  

14.4.4. Market Revenue and Forecast, by Route of Administration  

14.4.5. Market Revenue and Forecast, by Treatment Intent  

14.4.6. Market Revenue and Forecast, by End-User  

14.4.7. GCC

14.4.7.1. Market Revenue and Forecast, by Therapy Type  

14.4.7.2. Market Revenue and Forecast, by Drug Class Combination  

14.4.7.3. Market Revenue and Forecast, by Cancer Type  

14.4.7.4. Market Revenue and Forecast, by Route of Administration  

14.4.8. Market Revenue and Forecast, by Treatment Intent  

14.4.9. Market Revenue and Forecast, by End-User  

14.4.10. North Africa

14.4.10.1. Market Revenue and Forecast, by Therapy Type  

14.4.10.2. Market Revenue and Forecast, by Drug Class Combination  

14.4.10.3. Market Revenue and Forecast, by Cancer Type  

14.4.10.4. Market Revenue and Forecast, by Route of Administration  

14.4.11. Market Revenue and Forecast, by Treatment Intent  

14.4.12. Market Revenue and Forecast, by End-User  

14.4.13. South Africa

14.4.13.1. Market Revenue and Forecast, by Therapy Type  

14.4.13.2. Market Revenue and Forecast, by Drug Class Combination  

14.4.13.3. Market Revenue and Forecast, by Cancer Type  

14.4.13.4. Market Revenue and Forecast, by Route of Administration  

14.4.13.5. Market Revenue and Forecast, by Treatment Intent  

14.4.13.6. Market Revenue and Forecast, by End-User  

14.4.14. Rest of MEA

14.4.14.1. Market Revenue and Forecast, by Therapy Type  

14.4.14.2. Market Revenue and Forecast, by Drug Class Combination  

14.4.14.3. Market Revenue and Forecast, by Cancer Type  

14.4.14.4. Market Revenue and Forecast, by Route of Administration  

14.4.14.5. Market Revenue and Forecast, by Treatment Intent  

14.4.14.6. Market Revenue and Forecast, by End-User  

14.5. Latin America

14.5.1. Market Revenue and Forecast, by Therapy Type  

14.5.2. Market Revenue and Forecast, by Drug Class Combination  

14.5.3. Market Revenue and Forecast, by Cancer Type  

14.5.4. Market Revenue and Forecast, by Route of Administration  

14.5.5. Market Revenue and Forecast, by Treatment Intent  

14.5.6. Market Revenue and Forecast, by End-User  

14.5.7. Brazil

14.5.7.1. Market Revenue and Forecast, by Therapy Type  

14.5.7.2. Market Revenue and Forecast, by Drug Class Combination  

14.5.7.3. Market Revenue and Forecast, by Cancer Type  

14.5.7.4. Market Revenue and Forecast, by Route of Administration  

14.5.8. Market Revenue and Forecast, by Treatment Intent  

14.5.8.1. Market Revenue and Forecast, by End-User  

14.5.9. Rest of LATAM

14.5.9.1. Market Revenue and Forecast, by Therapy Type  

14.5.9.2. Market Revenue and Forecast, by Drug Class Combination  

14.5.9.3. Market Revenue and Forecast, by Cancer Type  

14.5.9.4. Market Revenue and Forecast, by Route of Administration  

14.5.9.5. Market Revenue and Forecast, by Treatment Intent  

14.5.9.6. Market Revenue and Forecast, by End-User  

Chapter 15. Company Profiles

15.1. Roche Holding AG

15.1.1. Company Overview

15.1.2. Product Offerings

15.1.3. Financial Performance

15.1.4. Recent Initiatives

15.2. Merck & Co., Inc. (Keytruda)

15.2.1. Company Overview

15.2.2. Product Offerings

15.2.3. Financial Performance

15.2.4. Recent Initiatives

15.3. Bristol Myers Squibb

15.3.1. Company Overview

15.3.2. Product Offerings

15.3.3. Financial Performance

15.3.4. Recent Initiatives

15.4. Pfizer Inc.

15.4.1. Company Overview

15.4.2. Product Offerings

15.4.3. Financial Performance

15.4.4. Recent Initiatives

15.5. AstraZeneca plc

15.5.1. Company Overview

15.5.2. Product Offerings

15.5.3. Financial Performance

15.5.4. Recent Initiatives

15.6. Abbott

15.6.1. Company Overview

15.6.2. Product Offerings

15.6.3. Financial Performance

15.6.4. Recent Initiatives

15.7. Novartis AG

15.7.1. Company Overview

15.7.2. Product Offerings

15.7.3. Financial Performance

15.7.4. Recent Initiatives

15.8. Eli Lilly and Company

15.8.1. Company Overview

15.8.2. Product Offerings

15.8.3. Financial Performance

15.8.4. Recent Initiatives

15.9. Amgen Inc.

15.9.1. Company Overview

15.9.2. Product Offerings

15.9.3. Financial Performance

15.9.4. Recent Initiatives

15.10. Gilead Sciences, Inc.

15.10.1. Company Overview

15.10.2. Product Offerings

15.10.3. Financial Performance

15.10.4. Recent Initiatives

Chapter 16. Research Methodology

16.1. Primary Research

16.2. Secondary Research

16.3. Assumptions

Chapter 17. Appendix

17.1. About Us

17.2. Glossary of Terms

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Frequently Asked Questions

The major players in the oncology combination therapy market include Roche Holding AG, Merck & Co., Inc. (Keytruda), Bristol Myers Squibb, Pfizer Inc., AstraZeneca plc, Novartis AG, Eli Lilly and Company, Amgen Inc., Gilead Sciences, Inc., Seagen Inc. (Pfizer), Genentech, Inc., BeiGene, Ltd., Sanofi S.A., Johnson & Johnson (Janssen Oncology), Takeda Pharmaceutical Company, GlaxoSmithKline plc (GSK), Moderna, Inc. (for combination mRNA immunotherapies), Arcus Biosciences, Inc., Mirati Therapeutics, Inc., and Incyte Corporation.

The driving factors of the oncology combination therapy market are the rising resistance to monotherapy, which are boosting the demand for combination treatments. Ongoing advancements in immunotherapy, targeted therapies, and personalized medicine are enhancing the efficacy of combination therapies and survival outcomes for patients.

North America region will lead the global oncology combination therapy market during the forecast period 2025 to 2034.

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