Pain Management Drugs Top Companies - Benchmarking, Business Strategy, Deal Strategy, Recent Development, Patent Strategy, Management Outlook

Date : June 2024

The global pain management drugs market size was valued at USD 81.15 billion in 2023 and is expected to reach around USD 120.16 billion by 2033 with a CAGR of 4% from 2024 to 2033.

Here are top comapanies of pain management drugs market:

1. Endo International plc

Headquarter: Ireland

Telephone: +353 1 268 2000

Website: www.endo.com

Company Shanpshot: Endo International plc

Snapshot Description
Year Of Inception 1997
Primary Business Pharmaceutical Manufacturing
Geographical Presence North America
Strategic Moves Product Launch


Endo International Plc is a specialty healthcare company that operates through its various subsidiaries to develop, manufacture, and commercialize a diverse range of products in the pharmaceutical industry. The company focuses on branded pharmaceuticals, generic pharmaceuticals, sterile injectables, and other healthcare products. Endo's product portfolio includes both branded and generic pharmaceuticals, catering to various medical specialties and therapeutic areas. In the U.S., the company sells generic products in categories such as urology, pain management, orthopedics, endocrinology, CNS disorders, cancer, cardiovascular diseases, and women's health. These generic products provide affordable alternatives to brand-name medications and address a wide range of medical conditions. Furthermore, Endo offers branded pharmaceuticals that target specific therapeutic areas including urology, orthopedics, endocrine disorders, and pain management. These branded products provide specialized treatment options for patients and contribute to the company's diversified product portfolio. In addition to prescription medications, Endo provides over the counter (OTC) products, which include dermatological products and anti-infectives. These OTC offerings cater to consumers' needs for self-care and non-prescription treatments.

Endo distributes its products through independent wholesale distributors to various channels, including retailers, government agencies, doctors, clinics, independent retail and specialty pharmacies, and independent specialty distributors. This broad distribution network ensures the availability of Endo's products to healthcare providers and patients. Headquartered in Dublin, Ireland, Endo operates globally and serves the healthcare industry with a wide range of pharmaceutical products. The company's focus on developing and commercializing both branded and generic medications allow it to address the diverse needs of patients and healthcare professionals.

2. GSK plc.

Headquarter: United Kingdom

Telephone: +44 20 80475000

Website: www.gsk.com

Company Shanpshot: GSK plc.

Snapshot Description
Year Of Inception 2000
Primary Business Pharmaceutical Biotechnology
Geographical Presence North America, LAMEA, Europe, RoW
Strategic Moves Partnership, Agreement


GlaxoSmithKline plc is a multinational British pharmaceutical and biotechnology company headquartered in London, England. Glaxo Wellcome and SmithKline Beecham merged in 2000 to form Glaxo Wellcome. GSK is the tenth largest pharmaceutical firm in the world and ranks 294 on the 2022 Fortune Global 500, behind other pharmaceutical companies. The company develops novel vaccines and specialty medications to help prevent and cure illness. Its research and development are focused on immune system science, human genetics, and innovative technologies. The company has over 94,066 employees around the world.

GSK plc offers diverse types of segments including pharmaceuticals, vaccines, and consumer healthcare. Its R&D strategy focuses on immune system research, the utilization of human genetics, and the use of advanced technologies such as AI and machine learning to deliver transformational medicines and vaccines. GSK's biopharma R&D pipeline contains 36 potential novel medicines and 19 vaccine prospects. With potential clinical assets in immune-mediated disorders, infectious diseases, and oncology, its immunology focus is strengthening and diversifying its portfolio.

GSK has a world-leading portfolio of infectious diseases medicines and vaccines in clinical trials. This reflects both its immunology focus and GSK's 70-year record of developing new research methodologies and technology to address disorders caused by bacteria, viruses, and parasites. Its 2019 joint venture with Pfizer created multiple complementary brand portfolios, driving it to the top of the global market share in over-the-counter (OTC) medicines, therapeutic oral health, and vitamins, minerals, and supplements. It delivered 28 first market launches of innovative products across its categories in 2020.

3. Pfizer Inc.

Headquarter: United States

Telephone: +1-800-879-3477

Website: www.pfizer.com

Company Shanpshot: Pfizer Inc.

Snapshot Description
Year Of Inception 1942
Primary Business The therapeutic area business segment includes vaccines, oncology, internal medicine, inflammation and immunology, rare disease
Geographical Presence North America, LAMEA, Europe, RoW
Strategic Moves Acquisition


Pfizer Inc is a leading biopharmaceutical company that discovers, develops, manufactures, and sells products to treat various medical conditions. It operates globally, with major manufacturing facilities located in various countries. In recent years, Pfizer has undergone significant restructuring, with the formation of a Consumer Healthcare JV and the spin-off of its Upjohn Business, resulting in a more focused approach to science-based innovative medicines and vaccines. At the beginning of 2021, the company reorganized its commercial operations into two operating segments: Biopharma, its innovative biopharmaceutical business, and PC1, its global contract development and manufacturing organization. Each operating segment is responsible for its commercial activities and is supported by global platform functions. Biopharma is the only reportable segment, with a geographic footprint across developed and emerging markets. The company uses the performance and earnings of the operating segments, among other factors, for performance evaluation and resource allocation. Prior-period information has been revised to conform to the current management structure.

Furthermore, Pfizer is focused on six sectors and continuously improving its ESG strategy to implement substantial impact over the next era which includes equitable access and pricing, equity & inclusion, climate change, product quality and safety, diversity, and business ethics.

  • Growth Strategy
    • Win the pharma digital race.
    • Deliver world-class science.
    • Change the business strategy
    • ake the initiative in the conversation
    • Unleash the strength of the people
  • Value: - The Company is relentlessly pursuing innovations that will improve patients' lives. Every day, innovate to make the world a more pleasant place. It was Charles Pfizer's aim from the beginning, and it remains true today.
  • Mission: - Its mission is to be the most valuable organization on earth to customers, patients, colleagues, businesses, partners, investors, and the communities wherein employees work and live.

4. Mallinckrodt

Headquarter: Ireland

Telephone: +353 1 6960000

Website: www.mallinckrodt.com

Company Shanpshot: Mallinckrodt

Snapshot Description
Year Of Inception 1867
Primary Business Pharmaceutical Manufacturing
Geographical Presence North America, LAMEA, Europe, RoW
Strategic Moves Collaboration


Mallinckrodt plc is a global pharmaceutical business consisting of several wholly owned subsidiaries. The company is dedicated to developing, manufacturing, marketing, and distributing specialty pharmaceutical products and therapies. Company areas of focus encompass a wide range of medical specialties, including neurology, rheumatology, hepatology, nephrology, pulmonology, ophthalmology, oncology, immunotherapy, neonatal respiratory critical care, analgesics, cultured skin substitutes, and gastrointestinal products.

Operating in two distinct segments, Specialty Brands and Specialty Generics, they offer a diverse portfolio of pharmaceutical solutions. The Specialty Brands segment focuses on innovative specialty pharmaceutical brands, delivering breakthrough treatments for patients with specific medical needs. Within this segment, global external manufacturing operations are located at principal executive offices in Dublin, Ireland. Additionally, the Company maintains other key locations in the U.S., including in corporate shared services office in Hazelwood, Missouri, and Specialty Brands commercial headquarters in Bridgewater, New Jersey. On the other hand, the Company’s Specialty Generics segment specializes in niche specialty generic drugs and active pharmaceutical ingredients (APIs). This segment is supported by the headquarters and technical development center in Webster Groves, Missouri.

As a company, they are committed to transforming themselves into an innovation-driven biopharmaceutical enterprise. The primary objective is to improve outcomes for underserved patients with severe and critical conditions. Through ongoing research and development efforts, they strive to introduce new therapies and treatment options to address unmet medical needs. At Mallinckrodt, they prioritize the well-being of patients and are dedicated to enhancing their lives through pharmaceutical products and therapies.

5. Abbott

Headquarter: United States

Telephone: (224) 667-6100

Website: www.abbott.com

Company Shanpshot: Abbott

Snapshot Description
Year Of Inception 1888
Primary Business Nutrition, Diagnostics, Medical Devices, and Branded Generic Pharmaceuticals
Geographical Presence North America, LAMEA, Europe, RoW
Strategic Moves Approval


Abbott Laboratories is a global healthcare company headquartered in Abbott Park, Illinois, U.S. It focuses on the development, research, manufacturing, and distribution of various healthcare products. The company is divided into four business segments: Diagnostic Products, Nutritional Products, Established Pharmaceutical Products, and Medical Devices. The Established Pharmaceutical Products segment produces and sells branded generic medications in emerging markets outside the U.S. These products are distributed through various channels, including Abbott-owned centers, public warehouses, wholesalers, distributors, government agencies, healthcare facilities, pharmacies, and independent retailers. Some of these products are licensed or co-marketed by other companies.

The Diagnostic Products segment offers a wide range of diagnostic systems and tests that are marketed and sold globally. These products are distributed through various channels, including Abbott-owned centers, public warehouses, third-party distributors, blood banks, hospitals, commercial laboratories, clinics, physicians' offices, retailers, government agencies, alternate care testing sites, and plasma protein therapeutic companies.

The Nutritional Products segment develops, markets, and sells a diverse range of pediatric and adult nutritional items worldwide. These products are distributed through various channels, including Abbott-owned centers, third-party distributors, customers, institutions, wholesalers, retailers, healthcare facilities, and government organizations. The Medical Devices segment produces and sells a broad range of devices for the treatment of cardiovascular diseases, diabetes care products for diabetics, and neuromodulation devices for the management of chronic pain and mobility disorders worldwide. These products are usually marketed and sold directly to hospitals, ambulatory surgical centers, physicians' offices, distributors, and wholesalers through Abbott-controlled distribution centers and public warehouses in the U.S. Outside the U.S., sales are made either directly to customers or through distributors, depending on the market covered.

6. Teva Pharmaceutical Industries Ltd

Headquarter: Israel

Telephone: +27 11 055 0200

Website: www.tevapharm.com

Company Shanpshot: 

Snapshot Description
Year Of Inception 1901
Primary Business Generic medicines, specialty medicines, CNS, active pharmaceutical ingredients, respiratory, biosimilars, biologics, pain care, migraine, and oncology
Geographical Presence North America, Europe, and International Market
Strategic Moves Agreement


Teva Pharmaceuticals Has Been Developing & Producing Medicines to Help Improve People's Lives for Over a Century. They Are Committed to Being a Global Leader in Generic & Specialty Medicines with A Portfolio Of 3,600 Products in The Therapeutic Area. About 200 million People Around the World Take Teva Medicine Every Day. It Operates Through Three Business Segments Europe, North America, And International Markets. Each Component Manages the Company's Entire Product Portfolio in That Region, Including Generics, Specialty, And Over the Counter (OTC) Products. Teva Pharmaceutical Industries Ltd., Also Known as Teva Pharmaceuticals, Is an Israeli Pharmaceutical Firm Based in Petah Tikva. Its Primary Business Is Generic Medications, But It Also Deals in Active Pharmaceutical Ingredients And, To A Lesser Extent, Patented Pharmaceuticals.

Teva Pharmaceuticals Was the World's Second-Largest Generic Medicine Manufacturer and Eighth-Largest Pharmaceutical Firm In 2020. Teva Has Facilities in Israel, The U.S., Europe, Australia, And South America. The Tel Aviv Stock Exchange Is Where Teva Shares Are Traded. The Company Is a Pharmaceutical Research and Manufacturers of America (Pharma) Member.

Teva API, A Separate Business Entity of Teva Pharmaceutical Industries, Provides High-Quality Apis to Over 1,000 Clients Globally. Teva API's Portfolio Includes Over 400 High-Quality Apis Made At 16 States of The Art Production Sites Employing Over 5,000 Highly Skilled Professionals. To secure long-term supplies, Teva API Is Committed to Environmental, Health, And Safety (EHS) Problems. To Stay Ahead, Teva API Constantly Improves Its Methods. Its Focus on Efficiency Aims to Provide the Product with A Competitive Advantage in The Worldwide Marketplace. Because of large economies of scale and back-integration capabilities, Teva API Focuses on API Development, Production, And Product Lifecycle Management (PLM) Procedures. Chemical Synthesis, Fermentation, High Potency, Plant Extract, Synthetic Peptides, Vitamin D Derivatives, Prostaglandins, Analytical Science, Powder Technology, And Solid-3 State Characterization Are One of The Specialties.

7. Eli Lilly and Company

Headquarter: United States

Telephone: 0090-216-554-0000

Website: www.lilly.com

Company Shanpshot: Eli Lilly and Company

Snapshot Description
Year Of Inception 1876
Primary Business Pharmaceutical Product Manufacturing
Geographical Presence North America, Europe, Asia Pacific, and LAMEA
Strategic Moves Acquisition, and Collaboration


Eli Lilly and Company was founded on May 10, 1876, by Colonel Eli Lilly. The company was incorporated in Indiana in 1901. They use facilities in the U.S., Puerto Rico, and 7 other nations to produce and distribute their goods. The company sells its products in about 120 different nations. Currently, around 38000+ employees work globally with 6,521 in the U.S., 11;279 in Indianapolis, and 115 employees in Indiana, reported as of December 2022. The company’s R&D expenditure accounted for $7190.8 million in 2022. A new drug's research and development by Lilly typically cost around $2.6 billion. The majority of the company's products are distributed in the U.S. by wholesalers who cater to doctors, pharmacies, hospitals, and other healthcare providers. The company’s major three wholesale distributors in the U.S. are — Cardinal Health, Inc., McKesson Corporation, and AmerisourceBergen Corporation. The company operates in five major business segments: diabetes, oncology, immunology, neuroscience, and others. Lilly majorly focuses on the diabetes segment.

A global partnership between Lilly and Boehringer Ingelheim has resulted in the marketing and development of a variety of diabetes medications, including Trajenta, Basaglar, Basaglar, Jentadueto, Jardiance, Glyxambi, and Trijardy XR. They have collaborated with Incyte Corporation, Boehringer Ingelheim, and other market players for the development and marketing of pharmaceutical products. Lilly has signed acquisition agreements with Prevail, Dermira, Loxo, Rigel Pharmaceuticals, Inc., Protomer Technologies Inc., Merus N.V., Merus N.V., Kumquat Biosciences Inc., QILU Regor Therapeutics Inc, Entos Pharmaceuticals Inc., Evox Therapeutics Limited, Fochon Pharmaceuticals, Ltd, and several others.

8. AstraZeneca

Headquarter: United Kingdom

Telephone: +44 (0)20 3749 5000

Website: www.astrazeneca.com

Company Shanpshot: AstraZeneca

Snapshot Description
Year Of Inception 1999
Primary Business Pharmaceutical Product Manufacturing
Geographical Presence North America, Europe, Asia Pacific, and LAMEA
Strategic Moves Acquisition, and Collaboration


AstraZeneca is a public company. AstraZeneca Plc is a biopharmaceutical firm that focuses on the development, manufacturing, and marketing of a variety of prescription drugs. It develops medicines for, cardiovascular, respiratory, renal & metabolic diseases, cancer, autoimmune, infection & neurological diseases. AstraZeneca sells its medicines through wholly owned local marketing organizations, distributors, and representative offices in each country. The company markets its products to specialty care and primary care physicians. AstraZeneca's COVID-19 vaccine has been approved for conditional marketing or emergency use. The business is present across Europe, the Americas, Asia, Africa, and Australasia. AstraZeneca's headquarters are in Cambridge, Cambridgeshire, England. The business is present across Europe, the Americas, Asia, Africa, and Australasia. AstraZeneca's headquarters are in Cambridge, Cambridgeshire, England. As of 31 December 2021, AstraZeneca employed +45,000 people worldwide.

9. Novartis

Headquarter: Switzerland

Telephone: +41 61 324 11 11

Website: www.novartis.com

Company Shanpshot: Novartis

Snapshot Description
Year Of Inception 1996
Primary Business Pharmaceutical Product Manufacturing
Geographical Presence North America, Europe, Asia Pacific, and Row
Strategic Moves Partnership and Collaboration


Novartis AG is a healthcare company that focuses on the discovery, development, manufacture, and marketing of prescription and generic pharmaceutical products and eye care products. It provides drugs for the treatment of cancer, cardiovascular diseases, dermatological conditions, neurological disorders, ophthalmic and respiratory diseases, immune disorders, and infections, among others. The company offers generic medicines and biosimilars through Sandoz. Novartis conducts research in various disease areas through The Novartis Institutes for Biomedical Research (NIBR). The company operates through a network of subsidiaries and offices across the Americas, Europe, the Middle East, Africa, and Asia-Pacific. Gene therapies provided by Novartis are focused on advancing and commercializing gene therapies for patients and families devastated by rare and life-threatening neurological genetic diseases. The company got approval for its spinal muscular atrophy (SMA) gene therapy in the U.S., Israel, Brazil, Japan, and Europe. It has also developed a reproducible manufacturing process for gene therapies.

Novartis as a company engages with patients and healthcare professionals, healthcare professionals, and R&D.

  1. Patient and caregivers- This company collaborates with the global patient community to find innovative ways to prolong people's lives. Their enormous investment in R&D underscores their dedication to employing science-based innovation to address some of society's most difficult healthcare issues.
  2. Healthcare professionals- Novartis collaborates with healthcare professionals across the world to help them treat patients and address unmet needs.
  3. Research and Development- They focus on creating and discovering innovative treatments for critical patient requirements. Their disease area teams cooperate across scientific disciplines and organizations from the development of a therapy to early clinical development.

10. Johnson & Johnson Services, Inc.

Headquarter: New Jersey, United States

Telephone: +1(732) 524-0400

Website: www.jnj.com

Company Shanpshot: Johnson & Johnson Services, Inc.

Snapshot Description
Year Of Inception 1886
Primary Business Hospitals and Health Care Health Care, Medical Devices & Diagnostics, Pharmaceuticals, and Consumer
Geographical Presence North America, Asia Pacific, Europe, Row
Strategic Moves Acquisition


Johnson & Johnson Services Inc. manufactures items for the consumer healthcare market. Consumer health items, including those for vital and skin-related health and MedTech and pharmaceutical products, are just a few of the categories under which the company's products fall. Additionally, Johnson & Johnson sells their goods all over the world. The business sells its goods worldwide under the Johnson & Johnson brand name. Brunswick, New Jersey, in the U.S., serves as the company's headquarters.

The Company operates in three segments: Pharmaceutical, Consumer Health, and Medical Devices.

The consumer health category includes a wide range of personal healthcare items utilized in the markets for skin health/beauty, over-the-counter medications, baby care, oral care, women's health, and wound care. The NEUTROGENA, DR. CI: LABO, AVEENO, CLEAN & CLEAR, and OGX product lines are well-known Skin Beauty/Health companies.

The SUDAFED flu, cold, and allergy products, BENADRYL & ZYRTEC allergy products, MOTRIN IB ibuprofen products, NICORETTE smoking cessation products outside the U.S., ZARBEE'S products, and the PEPCID line of acid reflux products are some examples of over the counter (OTC) medications. The product lines for baby care include those from JOHNSON'S and AVEENO Baby.

Oral Care consists of the LISTERINE product line. Prominent women's health brands outside North America are STAYFREE & CAREFREE sanitary pads and o.b. tampon brands. Brands associated with wound care include NEOSPORIN First Aid and BAND-AID Adhesive Bandages. These goods are promoted to the public and offered for sale online (eCommerce) and to retailers and distributors worldwide.

Oncology (including hematologic malignancies, lung cancer, prostate cancer, and bladder cancer), Cardiovascular and Metabolism (including diabetes, thrombosis, and macular degeneration), Neuroscience (including mood disorders, neurodegenerative disorders, and schizophrenia), and Immunology are the six therapeutic areas that make up the pharmaceutical segment (e.g., Pulmonary Arterial Hypertension). Pharmaceuticals in this market sector are delivered directly to retailers, wholesalers, distributors, hospitals, and healthcare professionals for prescription usage.

The medical devices section includes a wide range of goods utilized in interventional solutions, orthopedics, surgery, and vision. The Orthopedics portfolio consists of products supporting Knees, Trauma, Spine, Hips, Sports & Others; the Surgery portfolios include advanced and general surgery offerings, solutions that focus on Breast Aesthetics (Mentor), Nose, Ear, and Throat procedures, and Johnson & Johnson Vi. Medical devices in Interventional Solutions include Electrophysiology products to treat cardiovascular diseases, Neurovascular Care that treats hemorrhagic and ischemic stroke; physicians, nurses, hospitals, eye care specialists, and clinics are the primary users of these items, which are delivered through hospitals, wholesalers, and retailers.