Knee Osteoarthritis Injectable Treatments Market Size, Share, and Trends 2025 to 2034

The global knee osteoarthritis (OA) injectable treatments market size is calculated at USD 3.46 billion in 2025 and is forecasted to reach around USD 6.37 billion by 2034, accelerating at a CAGR of 7.00% from 2025 to 2034. The North America market size surpassed USD 1.13 billion in 2024 and is expanding at a CAGR of 6.78% during the forecast period. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : June 2025  |  Report Code : 6270  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition               

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Knee Osteoarthritis (OA) Injectable Treatments Market 

5.1. COVID-19 Landscape: Knee Osteoarthritis (OA) Injectable Treatments Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By Product Type

8.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by Product Type, 2025-2034

8.1.1. Viscosupplements (Hyaluronic Acid Injections)

8.1.1.1. Market Revenue and Volume Forecast (2022-2034)

8.1.2. Corticosteroid Injections

8.1.2.1. Market Revenue and Volume Forecast (2022-2034)

8.1.3. Platelet-Rich Plasma (PRP) Injections

8.1.3.1. Market Revenue and Volume Forecast (2022-2034)

8.1.4. Stem Cell Therapy Injections

8.1.4.1. Market Revenue and Volume Forecast (2022-2034)

8.1.5. Botulinum Toxin Injections (off-label use in OA)

8.1.5.1. Market Revenue and Volume Forecast (2022-2034)

8.1.6. Combination Injections

8.1.6.1. Market Revenue and Volume Forecast (2022-2034)

8.1.7. Other Biologic Injections

8.1.7.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 9. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By Mechanism of Action

9.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by Mechanism of Action, 2025-2034

9.1.1. Lubrication (Viscosupplementation)

9.1.1.1. Market Revenue and Volume Forecast (2022-2034)

9.1.2. Anti-inflammatory (Corticosteroids, PRP)

9.1.2.1. Market Revenue and Volume Forecast (2022-2034)

9.1.3. Regenerative (PRP, Stem Cells, APS)

9.1.3.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 10. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By Disease Severity

10.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by Disease Severity, 2025-2034

10.1.1. Mild Knee OA

10.1.1.1. Market Revenue and Volume Forecast (2022-2034)

10.1.2. Moderate Knee OA

10.1.2.1. Market Revenue and Volume Forecast (2022-2034)

10.1.3. Severe Knee OA (Non-surgical candidates)

10.1.3.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 11. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By Age Group

11.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by Age Group, 2025-2034

11.1.1. <40 Years (sports injuries, early onset OA)

11.1.1.1. Market Revenue and Volume Forecast (2022-2034)

11.1.2. 40–60 Years

11.1.2.1. Market Revenue and Volume Forecast (2022-2034)

11.1.2. >60 Years

11.1.2.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 12. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By Duration / Dosing Frequency

12.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by Duration / Dosing Frequency, 2025-2034

12.1.1. Single-Dose Therapy

12.1.1.1. Market Revenue and Volume Forecast (2022-2034)

12.1.2. Multiple-Dose Regimens

12.1.2.1. Market Revenue and Volume Forecast (2022-2034)

12.1.2. Weekly over 3–5 weeks

12.1.2.1. Market Revenue and Volume Forecast (2022-2034)

 

12.1.2. Monthly (e.g., corticosteroids)

12.1.2.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 13. Global Knee Osteoarthritis (OA) Injectable Treatments Market, By End-use

13.1. Knee Osteoarthritis (OA) Injectable Treatments Market Revenue and Volume, by End-use, 2025-2034

13.1.1. Hospitals

13.1.1.1. Market Revenue and Volume Forecast (2022-2034)

13.1.2. Orthopedic Clinics

13.1.2.1. Market Revenue and Volume Forecast (2022-2034)

13.1.3. Ambulatory Surgical Centers (ASCs)

13.1.3.1. Market Revenue and Volume Forecast (2022-2034)

13.1.4. Sports Medicine Clinics

13.1.4.1. Market Revenue and Volume Forecast (2022-2034)

13.1.5. Research Institutes / Regenerative Medicine Centers

13.1.5.1. Market Revenue and Volume Forecast (2022-2034)

Chapter 14. Global Knee Osteoarthritis (OA) Injectable Treatments Market, Regional Estimates and Trend Forecast

14.1. North America

14.1.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.1.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.1.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.1.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.1.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.1.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.1.7. U.S.

14.1.7.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.1.7.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.1.7.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.1.7.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.1.8. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.1.8.1. Market Revenue and Volume Forecast, by End-use (2022-2034) 

14.1.9. Rest of North America

14.1.9.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.1.9.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.1.9.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.1.9.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.1.10. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.1.11. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.1.11.1.

14.2. Europe

14.2.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.2.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.2.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.2.4. Market Revenue and Volume Forecast, by Age Group (2022-2034) 

14.2.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.2.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.2.7.

14.2.8. UK

14.2.8.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.2.8.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.2.8.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.2.9. Market Revenue and Volume Forecast, by Age Group (2022-2034) 

14.2.10. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.2.10.1. Market Revenue and Volume Forecast, by End-use (2022-2034) 

14.2.11. Germany

14.2.11.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.2.11.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.2.11.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.2.12. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.2.13. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.2.14. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.2.14.1.

14.2.15. France

14.2.15.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.2.15.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.2.15.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.2.15.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.2.16. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.2.16.1. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.2.17. Rest of Europe

14.2.17.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.2.17.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.2.17.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.2.17.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.2.18. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.2.18.1. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.3. APAC

14.3.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.3.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.3.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.3.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.3.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.3.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.3.7. India

14.3.7.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.3.7.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.3.7.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.3.7.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.3.8. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.3.9. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.3.10. China

14.3.10.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.3.10.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.3.10.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.3.10.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.3.11. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.3.11.1. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.3.12. Japan

14.3.12.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.3.12.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.3.12.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.3.12.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.3.12.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.3.12.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.3.13. Rest of APAC

14.3.13.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.3.13.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.3.13.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.3.13.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.3.13.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.3.13.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.4. MEA

14.4.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.4.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.4.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.4.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.4.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.4.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.4.7. GCC

14.4.7.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.4.7.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.4.7.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.4.7.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.4.8. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.4.9. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.4.10. North Africa

14.4.10.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.4.10.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.4.10.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.4.10.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.4.11. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.4.12. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.4.13. South Africa

14.4.13.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.4.13.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.4.13.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.4.13.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.4.13.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.4.13.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.4.14. Rest of MEA

14.4.14.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.4.14.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.4.14.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.4.14.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.4.14.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.4.14.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.5. Latin America

14.5.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.5.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.5.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.5.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.5.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.5.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.5.7. Brazil

14.5.7.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.5.7.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.5.7.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.5.7.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.5.8. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.5.8.1. Market Revenue and Volume Forecast, by End-use (2022-2034)

14.5.9. Rest of LATAM

14.5.9.1. Market Revenue and Volume Forecast, by Product Type (2022-2034)

14.5.9.2. Market Revenue and Volume Forecast, by Mechanism of Action (2022-2034)

14.5.9.3. Market Revenue and Volume Forecast, by Disease Severity (2022-2034)

14.5.9.4. Market Revenue and Volume Forecast, by Age Group (2022-2034)

14.5.9.5. Market Revenue and Volume Forecast, by Duration / Dosing Frequency (2022-2034)

14.5.9.6. Market Revenue and Volume Forecast, by End-use (2022-2034)

Chapter 15. Company Profiles

15.1. Alcon, Inc.

15.1.1. Company Overview

15.1.2. Product Offerings

15.1.3. Financial Performance

15.1.4. Recent Initiatives

15.2. Allergan plc

15.2.1. Company Overview

15.2.2. Product Offerings

15.2.3. Financial Performance

15.2.4. Recent Initiatives

15.3. Anika Therapeutics, Inc.

15.3.1. Company Overview

15.3.2. Product Offerings

15.3.3. Financial Performance

15.3.4. Recent Initiatives

15.4. Arthrex, Inc.

15.4.1. Company Overview

15.4.2. Product Offerings

15.4.3. Financial Performance

15.4.4. Recent Initiatives

15.5. Bioventus, Inc.

15.5.1. Company Overview

15.5.2. Product Offerings

15.5.3. Financial Performance

15.5.4. Recent Initiatives

15.6. Ferring Pharmaceuticals Inc.

15.6.1. Company Overview

15.6.2. Product Offerings

15.6.3. Financial Performance

15.6.4. Recent Initiatives

15.7. Fidia Farmaceutici S.p.A.

15.7.1. Company Overview

15.7.2. Product Offerings

15.7.3. Financial Performance

15.7.4. Recent Initiatives

15.8. Flexion Therapeutics, Inc.

15.8.1. Company Overview

15.8.2. Product Offerings

15.8.3. Financial Performance

15.8.4. Recent Initiatives

15.9. Galderma S.A.

15.9.1. Company Overview

15.9.2. Product Offerings

15.9.3. Financial Performance

15.9.4. Recent Initiatives

15.10. Hyaltech Ltd.

15.10.1. Company Overview

15.10.2. Product Offerings

15.10.3. Financial Performance

15.10.4. Recent Initiatives

Chapter 16. Research Methodology

16.1. Primary Research

16.2. Secondary Research

16.3. Assumptions

Chapter 17. Appendix

17.1. About Us

17.2. Glossary of Terms

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Frequently Asked Questions

The global knee osteoarthritis (OA) injectable treatments market is expected to increase from USD 3.24 billion in 2024 to USD 6.37 billion by 2034.

The knee osteoarthritis (OA) injectable treatments marketis expected to grow at a compound annual growth rate (CAGR) of around 7.00% from 2025 to 2034.

The major players in the knee osteoarthritis (OA) injectable treatments market include Alcon, Inc., Allergan plc, Anika Therapeutics, Inc., Arthrex, Inc., Bioventus, Inc., Ferring Pharmaceuticals Inc., Fidia Farmaceutici S.p.A., Flexion Therapeutics, Inc., Galderma S.A., Hyaltech Ltd., Landec Corporation (LifeCore Biomedical, Inc.), Meiji Seika Pharma Ltd., Merz Pharmaceuticals GmbH (Merz Aesthetics, Inc.), OrthogenRx, Inc., Roche Holding AG (F. Hoffmann-La Roche AG), Royal Biologics, Sanofi S.A., Teva Pharmaceutical Industries Ltd., and Zimmer Biomet.

The driving factors of the knee osteoarthritis (OA) injectable treatments market are the growing preference for outpatient care and efforts to develop new delivery systems are accelerating the adoption of injectable therapies for osteoarthritis.

North America region will lead the global knee osteoarthritis (OA) injectable treatments market during the forecast period 2025 to 2034.

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