Esophageal Cancer Market Size, Share, and Trends 2025 to 2034

The global esophageal cancer market size is calculated at USD 16.65 billion in 2025 and is forecasted to reach around USD 34.04 billion by 2034, accelerating at a CAGR of 8.27% from 2025 to 2034. The North America market size surpassed USD 6.15 billion in 2024 and is expanding at a CAGR of 8.41% during the forecast period. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : July 2025  |  Report Code : 6348  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

5.1. Market Dynamics

5.1.1. Market Drivers

5.1.2. Market Restraints

5.1.3. Market Opportunities

5.2. Porter’s Five Forces Analysis

5.2.1. Bargaining power of suppliers

5.2.2. Bargaining power of buyers

5.2.3. Threat of substitute

5.2.4. Threat of new entrants

5.2.5. Degree of competition

Chapter 6. Competitive Landscape

6.1.1. Company Market Share/Positioning Analysis

6.1.2. Key Strategies Adopted by Players

6.1.3. Vendor Landscape

6.1.3.1. List of Suppliers

6.1.3.2. List of Buyers

Chapter 7. Global Esophageal Cancer Market, By Cancer Type

7.1. Esophageal Cancer Market, by Cancer Type

7.1.1. Adenocarcinoma 

7.1.1.1. Market Revenue and Forecast

7.1.2. Squamous Cell Carcinoma

7.1.2.1. Market Revenue and Forecast

7.1.3. Others (e.g., small cell carcinoma)

7.1.3.1. Market Revenue and Forecast

Chapter 8. Global Esophageal Cancer Market, By Diagnosis

8.1. Esophageal Cancer Market, by Diagnosis

8.1.1. Endoscopy

8.1.1.1. Market Revenue and Forecast

8.1.2. Biopsy

8.1.2.1. Market Revenue and Forecast

8.1.3. Barium Swallow (Esophagram)

8.1.3.1. Market Revenue and Forecast

8.1.4. Imaging (CT, PET, MRI)

8.1.4.1. Market Revenue and Forecast

8.1.5. Esophageal Manometry

8.1.5.1. Market Revenue and Forecast

8.1.6. Blood Tests

8.1.6.1. Market Revenue and Forecast

Chapter 9. Global Esophageal Cancer Market, By Treatment

9.1. Esophageal Cancer Market, by Treatment

9.1.1. Therapy Type 

9.1.1.1. Market Revenue and Forecast

9.1.2. Drug Class

9.1.2.1. Market Revenue and Forecast

Chapter 10. Global Esophageal Cancer Market, By Stage

10.1. Esophageal Cancer Market, by Stage

10.1.1. Stage 0 (Carcinoma in situ)

10.1.1.1. Market Revenue and Forecast

10.1.2. Stage I

10.1.2.1. Market Revenue and Forecast

10.1.3. Stage II 

10.1.3.1. Market Revenue and Forecast

10.1.4. Stage III

10.1.4.1. Market Revenue and Forecast

10.1.5. Stage IV (Metastatic)

10.1.5.1. Market Revenue and Forecast

Chapter 11. Global Esophageal Cancer Market, By Route of Administration

11.1. Esophageal Cancer Market, by Route of Administration

11.1.1. Oral 

11.1.1.1. Market Revenue and Forecast

11.1.2. Intravenous

11.1.2.1. Market Revenue and Forecast

11.1.3. Others

11.1.3.1. Market Revenue and Forecast

Chapter 12. Global Esophageal Cancer Market, By End User

12.1. Esophageal Cancer Market, by End User

12.1.1. Hospitals 

12.1.1.1. Market Revenue and Forecast

12.1.2. Specialty Cancer Centers

12.1.2.1. Market Revenue and Forecast

12.1.3. Academic & Research Institutes

12.1.3.1. Market Revenue and Forecast

12.1.4. Ambulatory Surgical Centers (ASCs) (Fastest)

12.1.4.1. Market Revenue and Forecast

12.1.5. Homecare Settings

12.1.5.1. Market Revenue and Forecast

Chapter 13. Global Esophageal Cancer Market, By Distribution Channel

13.1. Esophageal Cancer Market, by Distribution Channel

13.1.1. Hospital Pharmacies

13.1.1.1. Market Revenue and Forecast

13.1.2. Retail Pharmacies

13.1.2.1. Market Revenue and Forecast

13.1.3. Online Pharmacies 

13.1.3.1. Market Revenue and Forecast

Chapter 14. Global Esophageal Cancer Market, Regional Estimates and Trend Forecast

14.1. North America

14.1.1. Market Revenue and Forecast, by Cancer Type

14.1.2. Market Revenue and Forecast, by Diagnosis

14.1.3. Market Revenue and Forecast, by Treatment

14.1.4. Market Revenue and Forecast, by Stage

14.1.5. Market Revenue and Forecast, by Route of Administration

14.1.6. Market Revenue and Forecast, by Distribution Channel

14.1.7. Market Revenue and Forecast, by End User

14.1.8. U.S.

14.1.8.1. Market Revenue and Forecast, by Cancer Type

14.1.8.2. Market Revenue and Forecast, by Diagnosis

14.1.8.3. Market Revenue and Forecast, by Treatment

14.1.8.4. Market Revenue and Forecast, by Stage

14.1.8.5. Market Revenue and Forecast, by Route of Administration

14.1.8.6. Market Revenue and Forecast, by Distribution Channel

14.1.8.7. Market Revenue and Forecast, by End User

14.1.9. Rest of North America

14.1.9.1. Market Revenue and Forecast, by Cancer Type

14.1.9.2. Market Revenue and Forecast, by Diagnosis

14.1.9.3. Market Revenue and Forecast, by Treatment

14.1.9.4. Market Revenue and Forecast, by Stage

14.1.9.5. Market Revenue and Forecast, by Route of Administration

14.1.9.6. Market Revenue and Forecast, by Distribution Channel

14.1.9.7. Market Revenue and Forecast, by End User

14.2. Europe

14.2.1. Market Revenue and Forecast, by Cancer Type

14.2.2. Market Revenue and Forecast, by Diagnosis

14.2.3. Market Revenue and Forecast, by Treatment

14.2.4. Market Revenue and Forecast, by Stage

14.2.5. Market Revenue and Forecast, by Route of Administration

14.2.6. Market Revenue and Forecast, by Distribution Channel

14.2.7. Market Revenue and Forecast, by End User

14.2.8. UK

14.2.8.1. Market Revenue and Forecast, by Cancer Type

14.2.8.2. Market Revenue and Forecast, by Diagnosis

14.2.8.3. Market Revenue and Forecast, by Treatment

14.2.8.4. Market Revenue and Forecast, by Stage

14.2.8.5. Market Revenue and Forecast, by Route of Administration

14.2.8.6. Market Revenue and Forecast, by Distribution Channel

14.2.8.7. Market Revenue and Forecast, by End User

14.2.9. Germany

14.2.9.1. Market Revenue and Forecast, by Cancer Type

14.2.9.2. Market Revenue and Forecast, by Diagnosis

14.2.9.3. Market Revenue and Forecast, by Treatment

14.2.9.4. Market Revenue and Forecast, by Stage

14.2.9.5. Market Revenue and Forecast, by Route of Administration

14.2.9.6. Market Revenue and Forecast, by Distribution Channel

14.2.9.7. Market Revenue and Forecast, by End User

14.2.10. France

14.2.10.1. Market Revenue and Forecast, by Cancer Type

14.2.10.2. Market Revenue and Forecast, by Diagnosis

14.2.10.3. Market Revenue and Forecast, by Treatment

14.2.10.4. Market Revenue and Forecast, by Stage

14.2.10.5. Market Revenue and Forecast, by Route of Administration

14.2.10.6. Market Revenue and Forecast, by Distribution Channel

14.2.10.7. Market Revenue and Forecast, by End User

14.2.11. Rest of Europe

14.2.11.1. Market Revenue and Forecast, by Cancer Type

14.2.11.2. Market Revenue and Forecast, by Diagnosis

14.2.11.3. Market Revenue and Forecast, by Treatment

14.2.11.4. Market Revenue and Forecast, by Stage

14.2.11.5. Market Revenue and Forecast, by Route of Administration

14.2.11.6. Market Revenue and Forecast, by Distribution Channel

14.2.11.7. Market Revenue and Forecast, by End User

14.3. APAC

14.3.1. Market Revenue and Forecast, by Cancer Type

14.3.2. Market Revenue and Forecast, by Diagnosis

14.3.3. Market Revenue and Forecast, by Treatment

14.3.4. Market Revenue and Forecast, by Stage

14.3.5. Market Revenue and Forecast, by Route of Administration

14.3.6. Market Revenue and Forecast, by Distribution Channel

14.3.7. Market Revenue and Forecast, by End User

14.3.8. India

14.3.8.1. Market Revenue and Forecast, by Cancer Type

14.3.8.2. Market Revenue and Forecast, by Diagnosis

14.3.8.3. Market Revenue and Forecast, by Treatment

14.3.8.4. Market Revenue and Forecast, by Stage

14.3.8.5. Market Revenue and Forecast, by Route of Administration

14.3.8.6. Market Revenue and Forecast, by Distribution Channel

14.3.8.7. Market Revenue and Forecast, by End User

14.3.9. China

14.3.9.1. Market Revenue and Forecast, by Cancer Type

14.3.9.2. Market Revenue and Forecast, by Diagnosis

14.3.9.3. Market Revenue and Forecast, by Treatment

14.3.9.4. Market Revenue and Forecast, by Stage

14.3.9.5. Market Revenue and Forecast, by Route of Administration

14.3.9.6. Market Revenue and Forecast, by Distribution Channel

14.3.9.7. Market Revenue and Forecast, by End User

14.3.10. Japan

14.3.10.1. Market Revenue and Forecast, by Cancer Type

14.3.10.2. Market Revenue and Forecast, by Diagnosis

14.3.10.3. Market Revenue and Forecast, by Treatment

14.3.10.4. Market Revenue and Forecast, by Stage

14.3.10.5. Market Revenue and Forecast, by Route of Administration

14.3.10.6. Market Revenue and Forecast, by Distribution Channel

14.3.10.7. Market Revenue and Forecast, by End User

14.3.11. Rest of APAC

14.3.11.1. Market Revenue and Forecast, by Cancer Type

14.3.11.2. Market Revenue and Forecast, by Diagnosis

14.3.11.3. Market Revenue and Forecast, by Treatment

14.3.11.4. Market Revenue and Forecast, by Stage

14.3.11.5. Market Revenue and Forecast, by Route of Administration

14.3.11.6. Market Revenue and Forecast, by Distribution Channel

14.3.11.7. Market Revenue and Forecast, by End User

14.4. MEA

14.4.1. Market Revenue and Forecast, by Cancer Type

14.4.2. Market Revenue and Forecast, by Diagnosis

14.4.3. Market Revenue and Forecast, by Treatment

14.4.4. Market Revenue and Forecast, by Stage

14.4.5. Market Revenue and Forecast, by Route of Administration

14.4.6. Market Revenue and Forecast, by Distribution Channel

14.4.7. Market Revenue and Forecast, by End User

14.4.8. GCC

14.4.8.1. Market Revenue and Forecast, by Cancer Type

14.4.8.2. Market Revenue and Forecast, by Diagnosis

14.4.8.3. Market Revenue and Forecast, by Treatment

14.4.8.4. Market Revenue and Forecast, by Stage

14.4.8.5. Market Revenue and Forecast, by Route of Administration

14.4.8.6. Market Revenue and Forecast, by Distribution Channel

14.4.8.7. Market Revenue and Forecast, by End User

14.4.9. North Africa

14.4.9.1. Market Revenue and Forecast, by Cancer Type

14.4.9.2. Market Revenue and Forecast, by Diagnosis

14.4.9.3. Market Revenue and Forecast, by Treatment

14.4.9.4. Market Revenue and Forecast, by Stage

14.4.9.5. Market Revenue and Forecast, by Route of Administration

14.4.9.6. Market Revenue and Forecast, by Distribution Channel

14.4.9.7. Market Revenue and Forecast, by End User

14.4.10. South Africa

14.4.10.1. Market Revenue and Forecast, by Cancer Type

14.4.10.2. Market Revenue and Forecast, by Diagnosis

14.4.10.3. Market Revenue and Forecast, by Treatment

14.4.10.4. Market Revenue and Forecast, by Stage

14.4.10.5. Market Revenue and Forecast, by Route of Administration

14.4.10.6. Market Revenue and Forecast, by Distribution Channel

14.4.10.7. Market Revenue and Forecast, by End User

14.4.11. Rest of MEA

14.4.11.1. Market Revenue and Forecast, by Cancer Type

14.4.11.2. Market Revenue and Forecast, by Diagnosis

14.4.11.3. Market Revenue and Forecast, by Treatment

14.4.11.4. Market Revenue and Forecast, by Stage

14.4.11.5. Market Revenue and Forecast, by Route of Administration

14.4.11.6. Market Revenue and Forecast, by Distribution Channel

14.4.11.7. Market Revenue and Forecast, by End User

14.5. Latin America

14.5.1. Market Revenue and Forecast, by Cancer Type

14.5.2. Market Revenue and Forecast, by Diagnosis

14.5.3. Market Revenue and Forecast, by Treatment

14.5.4. Market Revenue and Forecast, by Stage

14.5.5. Market Revenue and Forecast, by Route of Administration

14.5.6. Market Revenue and Forecast, by Distribution Channel

14.5.7. Market Revenue and Forecast, by End User

14.5.8. Brazil

14.5.8.1. Market Revenue and Forecast, by Cancer Type

14.5.8.2. Market Revenue and Forecast, by Diagnosis

14.5.8.3. Market Revenue and Forecast, by Treatment

14.5.8.4. Market Revenue and Forecast, by Stage

14.5.8.5. Market Revenue and Forecast, by Route of Administration

14.5.8.6. Market Revenue and Forecast, by Distribution Channel

14.5.8.7. Market Revenue and Forecast, by End User

14.5.9. Rest of LATAM

14.5.9.1. Market Revenue and Forecast, by Cancer Type

14.5.9.2. Market Revenue and Forecast, by Diagnosis

14.5.9.3. Market Revenue and Forecast, by Treatment

14.5.9.4. Market Revenue and Forecast, by Stage

14.5.9.5. Market Revenue and Forecast, by Route of Administration

14.5.9.6. Market Revenue and Forecast, by Distribution Channel

14.5.9.7. Market Revenue and Forecast, by End User

Chapter 15. Company Profiles

15.1. F. Hoffmann-La Roche Ltd

15.1.1. Company Overview

15.1.2. Product Offerings

15.1.3. Financial Performance

15.1.4. Recent Initiatives

15.2. Merck & Co., Inc.

15.2.1. Company Overview

15.2.2. Product Offerings

15.2.3. Financial Performance

15.2.4. Recent Initiatives

15.3. AstraZeneca plc

15.3.1. Company Overview

15.3.2. Product Offerings

15.3.3. Financial Performance

15.3.4. Recent Initiatives

15.4. Novartis AG

15.4.1. Company Overview

15.4.2. Product Offerings

15.4.3. Financial Performance

15.4.4. Recent Initiatives

15.5. Amgen Inc.

15.5.1. Company Overview

15.5.2. Product Offerings

15.5.3. Financial Performance

15.5.4. Recent Initiatives

15.6. Daiichi Sankyo Company, Limited

15.6.1. Company Overview

15.6.2. Product Offerings

15.6.3. Financial Performance

15.6.4. Recent Initiatives

15.7. Bayer AG

15.7.1. Company Overview

15.7.2. Product Offerings

15.7.3. Financial Performance

15.7.4. Recent Initiatives

15.8. Takeda Pharmaceutical Company Limited

15.8.1. Company Overview

15.8.2. Product Offerings

15.8.3. Financial Performance

15.8.4. Recent Initiatives

15.9. Illumina, Inc. (diagnostics)

15.9.1. Company Overview

15.9.2. Product Offerings

15.9.3. Financial Performance

15.9.4. Recent Initiatives

15.10. Thermo Fisher Scientific Inc. (diagnostics)

15.10.1. Company Overview

15.10.2. Product Offerings

15.10.3. Financial Performance

15.10.4. Recent Initiatives

Chapter 16. Research Methodology

16.1. Primary Research

16.2. Secondary Research

16.3. Assumptions

Chapter 17. Appendix

17.1. About Us

17.2. Glossary of Terms

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Frequently Asked Questions

The global esophageal cancer market is expected to increase from USD 15.38 billion in 2024 to USD 34.04 billion by 2034.

The esophageal cancer market is expected to grow at a compound annual growth rate (CAGR) of around 2.90% from 2025 to 2034.

The major players in the esophageal cancer market include F. Hoffmann-La Roche Ltd, Merck & Co., Inc., Bristol-Myers Squibb Company, Pfizer Inc., AstraZeneca plc, Eli Lilly and Company, Novartis AG, Amgen Inc., Johnson & Johnson (Janssen Biotech), Daiichi Sankyo Company, Limited, GlaxoSmithKline plc (GSK), Bayer AG, AbbVie Inc., Takeda Pharmaceutical Company Limited, Illumina, Inc. (diagnostics), and Thermo Fisher Scientific Inc. (diagnostics).

The driving factors of the esophageal cancer market are the increased patient numbers and risk factors like smoking, alcohol use, and poor diet boost demand for diagnostics, therapies, and advanced treatments in both developed and developing healthcare sectors.

North America region will lead the global esophageal cancer market during the forecast period 2025 to 2034.

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