Single Dose Gene Therapy Market Size, Share, and Trends 2025 to 2034

Discover how the single-dose gene therapy market is transforming healthcare with curative therapies for rare and chronic genetic diseases. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : July 2025  |  Report Code : 6362  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Single-Dose Gene Therapy Market 

5.1. COVID-19 Landscape: Single-Dose Gene Therapy Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Single-Dose Gene Therapy Market, By Therapy Type

8.1. Single-Dose Gene Therapy Market, by Therapy Type

8.1.1. In Vivo Gene Therapy

8.1.1.1. Market Revenue and Forecast

8.1.2. Ex Vivo Gene Therapy

8.1.2.1. Market Revenue and Forecast

Chapter 9. Global Single-Dose Gene Therapy Market, By Vector Type

9.1. Single-Dose Gene Therapy Market, by Vector Type

9.1.1. AAV-based Vectors

9.1.1.1. Market Revenue and Forecast

9.1.2. Lentiviral Vectors

9.1.2.1. Market Revenue and Forecast

9.1.3. Retroviral Vectors             

9.1.3.1. Market Revenue and Forecast

9.1.4. Non-Viral Vectors (plasmid, nanoparticle)

9.1.4.1. Market Revenue and Forecast

Chapter 10. Global Single-Dose Gene Therapy Market, By Disease Area

10.1. Single-Dose Gene Therapy Market, by Disease Area

10.1.1. Neuromuscular Disorders (e.g., SMA)

10.1.1.1. Market Revenue and Forecast

10.1.2. Ophthalmology (e.g., inherited retinal diseases)

10.1.2.1. Market Revenue and Forecast

10.1.3. Hematologic Disorders (e.g., Hemophilia A/B) 

10.1.3.1. Market Revenue and Forecast

10.1.4. Metabolic Disorders (e.g., OTC deficiency, Fabry)

10.1.4.1. Market Revenue and Forecast

10.1.5. Cardiovascular Disorders

10.1.5.1. Market Revenue and Forecast

10.1.6. CNS Disorders (e.g., MLD, Batten disease)

10.1.6.1. Market Revenue and Forecast

10.1.7. Others (e.g., rare pediatric diseases)

10.1.7.1. Market Revenue and Forecast

Chapter 11. Global Single-Dose Gene Therapy Market, By Patient Type

11.1. Single-Dose Gene Therapy Market, by Patient Type

11.1.1. Pediatric (Largest)

11.1.1.1. Market Revenue and Forecast

11.1.2. Adult

11.1.2.1. Market Revenue and Forecast

Chapter 12. Global Single-Dose Gene Therapy Market, By Route of Administration

12.1. Single-Dose Gene Therapy Market, by Route of Administration

12.1.1. Intravenous (IV) 

12.1.1.1. Market Revenue and Forecast

12.1.2. Intrathecal (IT)

12.1.2.1. Market Revenue and Forecast

12.1.3. Subretinal (for ocular therapies)

12.1.3.1. Market Revenue and Forecast

12.1.4. Intramuscular / Localized Delivery

12.1.4.1. Market Revenue and Forecast

Chapter 13. Global Single-Dose Gene Therapy Market, By End-User

13.1. Single-Dose Gene Therapy Market, by End-User

13.1.1. Hospitals & Specialty Clinics (Largest)

13.1.1.1. Market Revenue and Forecast

13.1.2. Academic & Research Institutions

13.1.2.1. Market Revenue and Forecast

13.1.3. Contract Development & Manufacturing Organizations (CDMOs)

13.1.3.1. Market Revenue and Forecast

Chapter 14. Global Single-Dose Gene Therapy Market, Regional Estimates and Trend Forecast

14.1. North America

14.1.1. Market Revenue and Forecast, by Therapy Type

14.1.2. Market Revenue and Forecast, by Vector Type

14.1.3. Market Revenue and Forecast, by Disease Area

14.1.4. Market Revenue and Forecast, by Patient Type

14.1.5. Market Revenue and Forecast, by Route of Administration

14.1.6. Market Revenue and Forecast, by End-User

14.1.7. U.S.

14.1.7.1. Market Revenue and Forecast, by Therapy Type

14.1.7.2. Market Revenue and Forecast, by Vector Type

14.1.7.3. Market Revenue and Forecast, by Disease Area

14.1.7.4. Market Revenue and Forecast, by Patient Type

14.1.8. Market Revenue and Forecast, by Route of Administration

14.1.8.1. Market Revenue and Forecast, by End-User  

14.1.9. Rest of North America

14.1.9.1. Market Revenue and Forecast, by Therapy Type

14.1.9.2. Market Revenue and Forecast, by Vector Type

14.1.9.3. Market Revenue and Forecast, by Disease Area

14.1.9.4. Market Revenue and Forecast, by Patient Type

14.1.10. Market Revenue and Forecast, by Route of Administration

14.1.11. Market Revenue and Forecast, by End-User

14.1.11.1.

14.2. Europe

14.2.1. Market Revenue and Forecast, by Therapy Type

14.2.2. Market Revenue and Forecast, by Vector Type

14.2.3. Market Revenue and Forecast, by Disease Area

14.2.4. Market Revenue and Forecast, by Patient Type  

14.2.5. Market Revenue and Forecast, by Route of Administration

14.2.6. Market Revenue and Forecast, by End-User

14.2.7.

14.2.8. UK

14.2.8.1. Market Revenue and Forecast, by Therapy Type

14.2.8.2. Market Revenue and Forecast, by Vector Type

14.2.8.3. Market Revenue and Forecast, by Disease Area

14.2.9. Market Revenue and Forecast, by Patient Type  

14.2.10. Market Revenue and Forecast, by Route of Administration

14.2.10.1. Market Revenue and Forecast, by End-User  

14.2.11. Germany

14.2.11.1. Market Revenue and Forecast, by Therapy Type

14.2.11.2. Market Revenue and Forecast, by Vector Type

14.2.11.3. Market Revenue and Forecast, by Disease Area

14.2.12. Market Revenue and Forecast, by Patient Type

14.2.13. Market Revenue and Forecast, by Route of Administration

14.2.14. Market Revenue and Forecast, by End-User

14.2.14.1.

14.2.15. France

14.2.15.1. Market Revenue and Forecast, by Therapy Type

14.2.15.2. Market Revenue and Forecast, by Vector Type

14.2.15.3. Market Revenue and Forecast, by Disease Area

14.2.15.4. Market Revenue and Forecast, by Patient Type

14.2.16. Market Revenue and Forecast, by Route of Administration

14.2.16.1. Market Revenue and Forecast, by End-User

14.2.17. Rest of Europe

14.2.17.1. Market Revenue and Forecast, by Therapy Type

14.2.17.2. Market Revenue and Forecast, by Vector Type

14.2.17.3. Market Revenue and Forecast, by Disease Area

14.2.17.4. Market Revenue and Forecast, by Patient Type

14.2.18. Market Revenue and Forecast, by Route of Administration

14.2.18.1. Market Revenue and Forecast, by End-User

14.3. APAC

14.3.1. Market Revenue and Forecast, by Therapy Type

14.3.2. Market Revenue and Forecast, by Vector Type

14.3.3. Market Revenue and Forecast, by Disease Area

14.3.4. Market Revenue and Forecast, by Patient Type

14.3.5. Market Revenue and Forecast, by Route of Administration

14.3.6. Market Revenue and Forecast, by End-User

14.3.7. India

14.3.7.1. Market Revenue and Forecast, by Therapy Type

14.3.7.2. Market Revenue and Forecast, by Vector Type

14.3.7.3. Market Revenue and Forecast, by Disease Area

14.3.7.4. Market Revenue and Forecast, by Patient Type

14.3.8. Market Revenue and Forecast, by Route of Administration

14.3.9. Market Revenue and Forecast, by End-User

14.3.10. China

14.3.10.1. Market Revenue and Forecast, by Therapy Type

14.3.10.2. Market Revenue and Forecast, by Vector Type

14.3.10.3. Market Revenue and Forecast, by Disease Area

14.3.10.4. Market Revenue and Forecast, by Patient Type

14.3.11. Market Revenue and Forecast, by Route of Administration

14.3.11.1. Market Revenue and Forecast, by End-User

14.3.12. Japan

14.3.12.1. Market Revenue and Forecast, by Therapy Type

14.3.12.2. Market Revenue and Forecast, by Vector Type

14.3.12.3. Market Revenue and Forecast, by Disease Area

14.3.12.4. Market Revenue and Forecast, by Patient Type

14.3.12.5. Market Revenue and Forecast, by Route of Administration

14.3.12.6. Market Revenue and Forecast, by End-User

14.3.13. Rest of APAC

14.3.13.1. Market Revenue and Forecast, by Therapy Type

14.3.13.2. Market Revenue and Forecast, by Vector Type

14.3.13.3. Market Revenue and Forecast, by Disease Area

14.3.13.4. Market Revenue and Forecast, by Patient Type

14.3.13.5. Market Revenue and Forecast, by Route of Administration

14.3.13.6. Market Revenue and Forecast, by End-User

14.4. MEA

14.4.1. Market Revenue and Forecast, by Therapy Type

14.4.2. Market Revenue and Forecast, by Vector Type

14.4.3. Market Revenue and Forecast, by Disease Area

14.4.4. Market Revenue and Forecast, by Patient Type

14.4.5. Market Revenue and Forecast, by Route of Administration

14.4.6. Market Revenue and Forecast, by End-User

14.4.7. GCC

14.4.7.1. Market Revenue and Forecast, by Therapy Type

14.4.7.2. Market Revenue and Forecast, by Vector Type

14.4.7.3. Market Revenue and Forecast, by Disease Area

14.4.7.4. Market Revenue and Forecast, by Patient Type

14.4.8. Market Revenue and Forecast, by Route of Administration

14.4.9. Market Revenue and Forecast, by End-User

14.4.10. North Africa

14.4.10.1. Market Revenue and Forecast, by Therapy Type

14.4.10.2. Market Revenue and Forecast, by Vector Type

14.4.10.3. Market Revenue and Forecast, by Disease Area

14.4.10.4. Market Revenue and Forecast, by Patient Type

14.4.11. Market Revenue and Forecast, by Route of Administration

14.4.12. Market Revenue and Forecast, by End-User

14.4.13. South Africa

14.4.13.1. Market Revenue and Forecast, by Therapy Type

14.4.13.2. Market Revenue and Forecast, by Vector Type

14.4.13.3. Market Revenue and Forecast, by Disease Area

14.4.13.4. Market Revenue and Forecast, by Patient Type

14.4.13.5. Market Revenue and Forecast, by Route of Administration

14.4.13.6. Market Revenue and Forecast, by End-User

14.4.14. Rest of MEA

14.4.14.1. Market Revenue and Forecast, by Therapy Type

14.4.14.2. Market Revenue and Forecast, by Vector Type

14.4.14.3. Market Revenue and Forecast, by Disease Area

14.4.14.4. Market Revenue and Forecast, by Patient Type

14.4.14.5. Market Revenue and Forecast, by Route of Administration

14.4.14.6. Market Revenue and Forecast, by End-User

14.5. Latin America

14.5.1. Market Revenue and Forecast, by Therapy Type

14.5.2. Market Revenue and Forecast, by Vector Type

14.5.3. Market Revenue and Forecast, by Disease Area

14.5.4. Market Revenue and Forecast, by Patient Type

14.5.5. Market Revenue and Forecast, by Route of Administration

14.5.6. Market Revenue and Forecast, by End-User

14.5.7. Brazil

14.5.7.1. Market Revenue and Forecast, by Therapy Type

14.5.7.2. Market Revenue and Forecast, by Vector Type

14.5.7.3. Market Revenue and Forecast, by Disease Area

14.5.7.4. Market Revenue and Forecast, by Patient Type

14.5.8. Market Revenue and Forecast, by Route of Administration

14.5.8.1. Market Revenue and Forecast, by End-User

14.5.9. Rest of LATAM

14.5.9.1. Market Revenue and Forecast, by Therapy Type

14.5.9.2. Market Revenue and Forecast, by Vector Type

14.5.9.3. Market Revenue and Forecast, by Disease Area

14.5.9.4. Market Revenue and Forecast, by Patient Type

14.5.9.5. Market Revenue and Forecast, by Route of Administration

14.5.9.6. Market Revenue and Forecast, by End-User

Chapter 15. Company Profiles

15.1. InfuCare Rx

15.1.1. Company Overview

15.1.2. Product Offerings

15.1.3. Financial Performance

15.1.4. Recent Initiatives

15.2. BioScrip (now part of Option Care)

15.2.1. Company Overview

15.2.2. Product Offerings

15.2.3. Financial Performance

15.2.4. Recent Initiatives

15.3. Intramed Plus

15.3.1. Company Overview

15.3.2. Product Offerings

15.3.3. Financial Performance

15.3.4. Recent Initiatives

15.4. AlayaCare

15.4.1. Company Overview

15.4.2. Product Offerings

15.4.3. Financial Performance

15.4.4. Recent Initiatives

15.5. ContinuumRx

15.5.1. Company Overview

15.5.2. Product Offerings

15.5.3. Financial Performance

15.5.4. Recent Initiatives

15.6. CareCentrix

15.6.1. Company Overview

15.6.2. Product Offerings

15.6.3. Financial Performance

15.6.4. Recent Initiatives

15.7. Healix Infusion Therapy

15.7.1. Company Overview

15.7.2. Product Offerings

15.7.3. Financial Performance

15.7.4. Recent Initiatives

15.8. Nufactor (a FFF Enterprises company)

15.8.1. Company Overview

15.8.2. Product Offerings

15.8.3. Financial Performance

15.8.4. Recent Initiatives

15.9. PharMerica Infusion Services

15.9.1. Company Overview

15.9.2. Product Offerings

15.9.3. Financial Performance

15.9.4. Recent Initiatives

15.10. Infusion Associates

15.10.1. Company Overview

15.10.2. Product Offerings

15.10.3. Financial Performance

15.10.4. Recent Initiatives

Chapter 16. Research Methodology

16.1. Primary Research

16.2. Secondary Research

16.3. Assumptions

Chapter 17. Appendix

17.1. About Us

17.2. Glossary of Terms

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Frequently Asked Questions

The major players in the single-dose gene therapy market include Option Care Health, InfuCare Rx, Coram CVS (now part of Option Care), KabaFusion, BioScrip (now part of Option Care), Amerita (a PharMerica company), United Infusion , Soleo Health, Paragon Healthcare, PromptCare, ContinuumRx, CareCentrix , Chartwell Pennsylvania, Intramed Plus, AlayaCare, ClearSky Health, Healix Infusion Therapy, Nufactor (a FFF Enterprises company), PharMerica Infusion Services, and Infusion Associates.

The driving factors of the single-dose gene therapy market are the massive investment in biotech, strategic partnerships, and acquisitions enable R&D programs to advance more quickly from clinical trials to commercialization

North America region will lead the global single-dose gene therapy market during the forecast period 2025 to 2034.

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