Oligonucleotides Market Size, Share, and Trends 2025 to 2034

The global oligonucleotides market size is calculated at USD 4.79 billion in 2025 and is forecasted to reach around USD 14.54 billion by 2034, accelerating at a CAGR of 13.14% from 2025 to 2034. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : July 2025  |  Report Code : 6451  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology  

 2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Oligonucleotides Market 

5.1. COVID-19 Landscape: Oligonucleotides Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Oligonucleotides Market, By Product Type

8.1. Oligonucleotides Market Revenue and Volume, by Product Type

8.1.1. Therapeutic Oligonucleotides

8.1.1.1. Market Revenue and Volume Forecast  

8.1.2. Diagnostic Oligonucleotides

8.1.2.1. Market Revenue and Volume Forecast  

8.1.3. Research Oligonucleotides

8.1.3.1. Market Revenue and Volume Forecast  

Chapter 9. Global Oligonucleotides Market, By Application

9.1. Oligonucleotides Market Revenue and Volume, by Application

9.1.1. Drug Discovery & Development

9.1.1.1. Market Revenue and Volume Forecast  

9.1.2. Molecular Diagnostics

9.1.2.1. Market Revenue and Volume Forecast  

9.1.2. Gene Therapy

9.1.2.1. Market Revenue and Volume Forecast  

9.1.2. Research Applications (PCR, qPCR, NGS, etc.)

9.1.2.1. Market Revenue and Volume Forecast  

9.1.2. RNA-based Therapeutics

9.1.2.1. Market Revenue and Volume Forecast  

9.1.2. Cancer & Rare Disease Diagnostics

9.1.2.1. Market Revenue and Volume Forecast

Chapter 10. Global Oligonucleotides Market, By Manufacturing Technology

10.1. Oligonucleotides Market Revenue and Volume, by Manufacturing Technology

10.1.1. Solid Phase Oligonucleotide Synthesis

10.1.1.1. Market Revenue and Volume Forecast  

10.1.2. Solution Phase Synthesis

10.1.2.1. Market Revenue and Volume Forecast  

10.1.3. Microarray-Based Synthesis

10.1.3.1. Market Revenue and Volume Forecast  

10.1.4. Enzymatic Synthesis

10.1.4.1. Market Revenue and Volume Forecast  

Chapter 11. Global Oligonucleotides Market, By End-User

11.1. Oligonucleotides Market Revenue and Volume, by End-User

11.1.1. Pharmaceutical & Biotechnology Companies

11.1.1.1. Market Revenue and Volume Forecast  

11.1.2. Academic & Research Institutes

11.1.2.1. Market Revenue and Volume Forecast  

11.1.3. Diagnostic Laboratories

11.1.3.1. Market Revenue and Volume Forecast  

11.1.4. Contract Research Organizations (CROs)

11.1.4.1. Market Revenue and Volume Forecast  

11.1.5. Contract Manufacturing Organizations (CMOs)

11.1.5.1. Market Revenue and Volume Forecast  

Chapter 12. Global Oligonucleotides Market, By Delivery Mode

12.1. Oligonucleotides Market Revenue and Volume, by Delivery Mode

12.1.1. Injectable

12.1.1.1. Market Revenue and Volume Forecast  

12.1.2. Oral

12.1.2.1. Market Revenue and Volume Forecast  

12.1.3. Intranasal

12.1.3.1. Market Revenue and Volume Forecast  

12.1.4. Transdermal

12.1.4.1. Market Revenue and Volume Forecast  

Chapter 13. Global Oligonucleotides Market, By Sales Channel

13.1. Oligonucleotides Market Revenue and Volume, by Sales Channel

13.1.1. Direct Sales

13.1.1.1. Market Revenue and Volume Forecast  

13.1.2. Distributor/Third-Party Sales

13.1.2.1. Market Revenue and Volume Forecast  

13.1.3. Online Platforms

13.1.3.1. Market Revenue and Volume Forecast  

Chapter 14. Global Oligonucleotides Market, Regional Estimates and Trend Forecast

14.1. North America

14.1.1. Market Revenue and Volume Forecast, by Product Type  

14.1.2. Market Revenue and Volume Forecast, by Application  

14.1.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.1.4. Market Revenue and Volume Forecast, by End-User  

14.1.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.1.6. Market Revenue and Volume Forecast, by Sales Channel  

14.1.7.1. Market Revenue and Volume Forecast, by Product Type  

14.1.7.2. Market Revenue and Volume Forecast, by Application  

14.1.7.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.1.7.4. Market Revenue and Volume Forecast, by End-User  

14.1.8. Market Revenue and Volume Forecast, by Delivery Mode  

14.1.8.1. Market Revenue and Volume Forecast, by Sales Channel   

14.1.9. Rest of North America

14.1.9.1. Market Revenue and Volume Forecast, by Product Type  

14.1.9.2. Market Revenue and Volume Forecast, by Application  

14.1.9.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.1.9.4. Market Revenue and Volume Forecast, by End-User  

14.1.10. Market Revenue and Volume Forecast, by Delivery Mode  

14.1.11. Market Revenue and Volume Forecast, by Sales Channel  

14.2. Europe

14.2.1. Market Revenue and Volume Forecast, by Product Type  

14.2.2. Market Revenue and Volume Forecast, by Application  

14.2.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.2.4. Market Revenue and Volume Forecast, by End-User   

14.2.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.2.6. Market Revenue and Volume Forecast, by Sales Channel 

14.2.8. UK

14.2.8.1. Market Revenue and Volume Forecast, by Product Type  

14.2.8.2. Market Revenue and Volume Forecast, by Application  

14.2.8.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.2.9. Market Revenue and Volume Forecast, by End-User   

14.2.10. Market Revenue and Volume Forecast, by Delivery Mode  

14.2.10.1. Market Revenue and Volume Forecast, by Sales Channel   

14.2.11. Germany

14.2.11.1. Market Revenue and Volume Forecast, by Product Type  

14.2.11.2. Market Revenue and Volume Forecast, by Application  

14.2.11.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.2.12. Market Revenue and Volume Forecast, by End-User  

14.2.13. Market Revenue and Volume Forecast, by Delivery Mode  

14.2.14. Market Revenue and Volume Forecast, by Sales Channel

14.2.15. France

14.2.15.1. Market Revenue and Volume Forecast, by Product Type  

14.2.15.2. Market Revenue and Volume Forecast, by Application  

14.2.15.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.2.15.4. Market Revenue and Volume Forecast, by End-User  

14.2.16. Market Revenue and Volume Forecast, by Delivery Mode  

14.2.16.1. Market Revenue and Volume Forecast, by Sales Channel  

14.2.17. Rest of Europe

14.2.17.1. Market Revenue and Volume Forecast, by Product Type  

14.2.17.2. Market Revenue and Volume Forecast, by Application  

14.2.17.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.2.17.4. Market Revenue and Volume Forecast, by End-User  

14.2.18. Market Revenue and Volume Forecast, by Delivery Mode  

14.2.18.1. Market Revenue and Volume Forecast, by Sales Channel  

14.3. APAC

14.3.1. Market Revenue and Volume Forecast, by Product Type  

14.3.2. Market Revenue and Volume Forecast, by Application  

14.3.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.3.4. Market Revenue and Volume Forecast, by End-User  

14.3.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.3.6. Market Revenue and Volume Forecast, by Sales Channel  

14.3.7. India

14.3.7.1. Market Revenue and Volume Forecast, by Product Type  

14.3.7.2. Market Revenue and Volume Forecast, by Application  

14.3.7.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.3.7.4. Market Revenue and Volume Forecast, by End-User  

14.3.8. Market Revenue and Volume Forecast, by Delivery Mode  

14.3.9. Market Revenue and Volume Forecast, by Sales Channel  

14.3.10. China

14.3.10.1. Market Revenue and Volume Forecast, by Product Type  

14.3.10.2. Market Revenue and Volume Forecast, by Application  

14.3.10.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.3.10.4. Market Revenue and Volume Forecast, by End-User  

14.3.11. Market Revenue and Volume Forecast, by Delivery Mode  

14.3.11.1. Market Revenue and Volume Forecast, by Sales Channel  

14.3.12. Japan

14.3.12.1. Market Revenue and Volume Forecast, by Product Type  

14.3.12.2. Market Revenue and Volume Forecast, by Application  

14.3.12.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.3.12.4. Market Revenue and Volume Forecast, by End-User  

14.3.12.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.3.12.6. Market Revenue and Volume Forecast, by Sales Channel  

14.3.13. Rest of APAC

14.3.13.1. Market Revenue and Volume Forecast, by Product Type  

14.3.13.2. Market Revenue and Volume Forecast, by Application  

14.3.13.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.3.13.4. Market Revenue and Volume Forecast, by End-User  

14.3.13.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.3.13.6. Market Revenue and Volume Forecast, by Sales Channel  

14.4. MEA

14.4.1. Market Revenue and Volume Forecast, by Product Type  

14.4.2. Market Revenue and Volume Forecast, by Application  

14.4.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.4.4. Market Revenue and Volume Forecast, by End-User  

14.4.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.4.6. Market Revenue and Volume Forecast, by Sales Channel  

14.4.7. GCC

14.4.7.1. Market Revenue and Volume Forecast, by Product Type  

14.4.7.2. Market Revenue and Volume Forecast, by Application  

14.4.7.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.4.7.4. Market Revenue and Volume Forecast, by End-User  

14.4.8. Market Revenue and Volume Forecast, by Delivery Mode  

14.4.9. Market Revenue and Volume Forecast, by Sales Channel  

14.4.10. North Africa

14.4.10.1. Market Revenue and Volume Forecast, by Product Type  

14.4.10.2. Market Revenue and Volume Forecast, by Application  

14.4.10.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.4.10.4. Market Revenue and Volume Forecast, by End-User  

14.4.11. Market Revenue and Volume Forecast, by Delivery Mode  

14.4.12. Market Revenue and Volume Forecast, by Sales Channel  

14.4.13. South Africa

14.4.13.1. Market Revenue and Volume Forecast, by Product Type  

14.4.13.2. Market Revenue and Volume Forecast, by Application  

14.4.13.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.4.13.4. Market Revenue and Volume Forecast, by End-User  

14.4.13.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.4.13.6. Market Revenue and Volume Forecast, by Sales Channel  

14.4.14. Rest of MEA

14.4.14.1. Market Revenue and Volume Forecast, by Product Type  

14.4.14.2. Market Revenue and Volume Forecast, by Application  

14.4.14.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.4.14.4. Market Revenue and Volume Forecast, by End-User  

14.4.14.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.4.14.6. Market Revenue and Volume Forecast, by Sales Channel  

14.5. Latin America

14.5.1. Market Revenue and Volume Forecast, by Product Type  

14.5.2. Market Revenue and Volume Forecast, by Application  

14.5.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.5.4. Market Revenue and Volume Forecast, by End-User  

14.5.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.5.6. Market Revenue and Volume Forecast, by Sales Channel  

14.5.7. Brazil

14.5.7.1. Market Revenue and Volume Forecast, by Product Type  

14.5.7.2. Market Revenue and Volume Forecast, by Application  

14.5.7.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.5.7.4. Market Revenue and Volume Forecast, by End-User  

14.5.8. Market Revenue and Volume Forecast, by Delivery Mode  

14.5.8.1. Market Revenue and Volume Forecast, by Sales Channel  

14.5.9. Rest of LATAM

14.5.9.1. Market Revenue and Volume Forecast, by Product Type  

14.5.9.2. Market Revenue and Volume Forecast, by Application  

14.5.9.3. Market Revenue and Volume Forecast, by Manufacturing Technology  

14.5.9.4. Market Revenue and Volume Forecast, by End-User  

14.5.9.5. Market Revenue and Volume Forecast, by Delivery Mode  

14.5.9.6. Market Revenue and Volume Forecast, by Sales Channel  

Chapter 15. Company Profiles

15.1. Ionis Pharmaceuticals

15.1.1. Company Overview

15.1.2. Product Offerings

15.1.3. Financial Performance

15.1.4. Recent Initiatives

15.2. Bio-Synthesis Inc.

15.2.1. Company Overview

15.2.2. Product Offerings

15.2.3. Financial Performance

15.2.4. Recent Initiatives

15.3. Sarepta Therapeutics

15.3.1. Company Overview

15.3.2. Product Offerings

15.3.3. Financial Performance

15.3.4. Recent Initiatives

15.4. Bioneer Corporation

15.4.1. Company Overview

15.4.2. Product Offerings

15.4.3. Financial Performance

15.4.4. Recent Initiatives

15.5. GE Healthcare

15.5.1. Company Overview

15.5.2. Product Offerings

15.5.3. Financial Performance

15.5.4. Recent Initiatives

15.6. TriLink BioTechnologies

15.6.1. Company Overview

15.6.2. Product Offerings

15.6.3. Financial Performance

15.6.4. Recent Initiatives

15.7. Bio-Techne Corporation

15.7.1. Company Overview

15.7.2. Product Offerings

15.7.3. Financial Performance

15.7.4. Recent Initiatives

15.8. Roche Diagnostics

15.8.1. Company Overview

15.8.2. Product Offerings

15.8.3. Financial Performance

15.8.4. Recent Initiatives

15.9. GeneDesign, Inc.

15.9.1. Company Overview

15.9.2. Product Offerings

15.9.3. Financial Performance

15.9.4. Recent Initiatives

15.10. GenScript Biotech Corporation

15.10.1. Company Overview

15.10.2. Product Offerings

15.10.3. Financial Performance

15.10.4. Recent Initiatives

Chapter 16. Research Methodology

16.1. Primary Research

16.2. Secondary Research

16.3. Assumptions

Chapter 17. Appendix

17.1. About Us

17.2. Glossary of Terms

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Frequently Asked Questions

The oligonucleotides market size is expected to increase from USD 4.23 billion in 2024 to USD 14.54 billion by 2034.

The oligonucleotides market is expected to grow at a compound annual growth rate (CAGR) of around 13.14% from 2025 to 2034.

The major players in the oligonucleotides market include Ionis Pharmaceuticals, Alnylam Pharmaceuticals, Bio-Synthesis Inc., Thermo Fisher Scientific, Eurofins Genomics, Integrated DNA Technologies (IDT), Biogen, Sarepta Therapeutics, Nitto Denko (Nitto Avecia), Bioneer Corporation, LGC Biosearch Technologies, GE Healthcare, TriLink BioTechnologies, Bio-Techne Corporation, Exiqon (QIAGEN), GeneDesign, Inc., Agilent Technologies, Roche Diagnostics, AstraZeneca (via Ionis collaborations), and GenScript Biotech Corporation.

The driving factors of the oligonucleotides market are the rising cases of genetic disorders, cancer, and chronic diseases have boosted the demand for accurate diagnosis and treatment instruments.

North America region will lead the global oligonucleotides market during the forecast period 2025 to 2034.

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