Nucleic Acid Aptamers Market Size, Share, and Trends 2025 to 2034

The global nucleic acid aptamers market size is calculated at USD 302.44 million in 2025 and is forecasted to reach around USD 1,267.63 million by 2034, accelerating at a CAGR of 17.26% from 2025 to 2034. The North America market size surpassed USD 100.59 million in 2024 and is expanding at a CAGR of 17.41% during the forecast period. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : August 2025  |  Report Code : 6514  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology  

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Nucleic Acid Aptamers Market 

5.1. COVID-19 Landscape: Nucleic Acid Aptamers Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Nucleic Acid Aptamers Market, By Type

8.1. Nucleic Acid Aptamers Market Revenue and Volume, by Type

8.1.1. DNA Aptamers

8.1.1.1. Market Revenue and Volume Forecast

8.1.2. RNA Aptamers

8.1.2.1. Market Revenue and Volume Forecast

8.1.3. XNA Aptamers (Synthetic analogs)

8.1.3.1. Market Revenue and Volume Forecast

8.1.4. Others (e.g., Spiegelmers)

8.1.4.1. Market Revenue and Volume Forecast

Chapter 9. Global Nucleic Acid Aptamers Market, By Application

9.1. Nucleic Acid Aptamers Market Revenue and Volume, by Application

9.1.1. Therapeutics

9.1.1.1. Market Revenue and Volume Forecast

9.1.2. Diagnostics

9.1.2.1. Market Revenue and Volume Forecast

9.1.3. Research & Development

9.1.3.1. Market Revenue and Volume Forecast

9.1.4. Biosensors / Analytical Devices

9.1.4.1. Market Revenue and Volume Forecast

9.1.5. Others (e.g., Food Testing, Environmental Monitoring)

9.1.5.1. Market Revenue and Volume Forecast

Chapter 10. Global Nucleic Acid Aptamers Market, By Synthesis Method 

10.1. Nucleic Acid Aptamers Market Revenue and Volume, by Synthesis Method

10.1.1. SELEX (Systematic Evolution of Ligands by Exponential Enrichment)

10.1.1.1. Market Revenue and Volume Forecast

10.1.2. Conventional SELEX

10.1.2.1. Market Revenue and Volume Forecast

10.1.3. Cell-SELEX

10.1.3.1. Market Revenue and Volume Forecast

10.1.4. Capillary Electrophoresis-SELEX

10.1.4.1. Market Revenue and Volume Forecast

10.1.5. Microfluidic SELEX

10.1.5.1. Market Revenue and Volume Forecast

10.1.5. Non-SELEX-Based Methods

10.1.5.1. Market Revenue and Volume Forecast

Chapter 11. Global Nucleic Acid Aptamers Market, By Delivery Method

11.1. Nucleic Acid Aptamers Market Revenue and Volume, by Delivery Method

11.1.1. Conjugated Delivery (e.g., PEGylated, Nanoparticle-conjugated)

11.1.1.1. Market Revenue and Volume Forecast

11.1.2. Unmodified Free Aptamers

11.1.2.1. Market Revenue and Volume Forecast

11.1.3. Carrier-mediated Delivery

11.1.3.1. Market Revenue and Volume Forecast

11.1.4. Analog, MEMS and Others

11.1.4.1. Market Revenue and Volume Forecast

11.1.5. Others

11.1.5.1. Market Revenue and Volume Forecast

Chapter 12. Global Nucleic Acid Aptamers Market, By End User

12.1. Nucleic Acid Aptamers Market Revenue and Volume, by End User

12.1.1. Pharmaceutical & Biotechnology Companies

12.1.1.1. Market Revenue and Volume Forecast

12.1.2. Academic & Research Institutes

12.1.2.1. Market Revenue and Volume Forecast

12.1.3. Contract Research Organizations (CROs)

12.1.3.1. Market Revenue and Volume Forecast

12.1.4. Diagnostic Laboratories

12.1.4.1. Market Revenue and Volume Forecast

12.1.5. Others (Hospitals, Government Labs)

12.1.5.1. Market Revenue and Volume Forecast

Chapter 13. Global Nucleic Acid Aptamers Market, Regional Estimates and Trend Forecast

13.1. North America

13.1.1. Market Revenue and Volume Forecast, by Type

13.1.2. Market Revenue and Volume Forecast, by Application

13.1.3. Market Revenue and Volume Forecast, by Synthesis Method

13.1.4. Market Revenue and Volume Forecast, by Delivery Method

13.1.5. Market Revenue and Volume Forecast, by End User

13.1.6. U.S.

13.1.6.1. Market Revenue and Volume Forecast, by Type

13.1.6.2. Market Revenue and Volume Forecast, by Application

13.1.6.3. Market Revenue and Volume Forecast, by Synthesis Method

13.1.6.4. Market Revenue and Volume Forecast, by Delivery Method

13.1.6.5. Market Revenue and Volume Forecast, by End User  

13.1.7. Rest of North America

13.1.7.1. Market Revenue and Volume Forecast, by Type

13.1.7.2. Market Revenue and Volume Forecast, by Application

13.1.7.3. Market Revenue and Volume Forecast, by Synthesis Method

13.1.7.4. Market Revenue and Volume Forecast, by Delivery Method

13.1.7.5. Market Revenue and Volume Forecast, by End User

13.2. Europe

13.2.1. Market Revenue and Volume Forecast, by Type

13.2.2. Market Revenue and Volume Forecast, by Application

13.2.3. Market Revenue and Volume Forecast, by Synthesis Method

13.2.4. Market Revenue and Volume Forecast, by Delivery Method  

13.2.5. Market Revenue and Volume Forecast, by End User  

13.2.6. UK

13.2.6.1. Market Revenue and Volume Forecast, by Type

13.2.6.2. Market Revenue and Volume Forecast, by Application

13.2.6.3. Market Revenue and Volume Forecast, by Synthesis Method

13.2.7. Market Revenue and Volume Forecast, by Delivery Method  

13.2.8. Market Revenue and Volume Forecast, by End User  

13.2.9. Germany

13.2.9.1. Market Revenue and Volume Forecast, by Type

13.2.9.2. Market Revenue and Volume Forecast, by Application

13.2.9.3. Market Revenue and Volume Forecast, by Synthesis Method

13.2.10. Market Revenue and Volume Forecast, by Delivery Method

13.2.11. Market Revenue and Volume Forecast, by End User

13.2.12. France

13.2.12.1. Market Revenue and Volume Forecast, by Type

13.2.12.2. Market Revenue and Volume Forecast, by Application

13.2.12.3. Market Revenue and Volume Forecast, by Synthesis Method

13.2.12.4. Market Revenue and Volume Forecast, by Delivery Method

13.2.13. Market Revenue and Volume Forecast, by End User

13.2.14. Rest of Europe

13.2.14.1. Market Revenue and Volume Forecast, by Type

13.2.14.2. Market Revenue and Volume Forecast, by Application

13.2.14.3. Market Revenue and Volume Forecast, by Synthesis Method

13.2.14.4. Market Revenue and Volume Forecast, by Delivery Method

13.2.15. Market Revenue and Volume Forecast, by End User

13.3. APAC

13.3.1. Market Revenue and Volume Forecast, by Type

13.3.2. Market Revenue and Volume Forecast, by Application

13.3.3. Market Revenue and Volume Forecast, by Synthesis Method

13.3.4. Market Revenue and Volume Forecast, by Delivery Method

13.3.5. Market Revenue and Volume Forecast, by End User

13.3.6. India

13.3.6.1. Market Revenue and Volume Forecast, by Type

13.3.6.2. Market Revenue and Volume Forecast, by Application

13.3.6.3. Market Revenue and Volume Forecast, by Synthesis Method

13.3.6.4. Market Revenue and Volume Forecast, by Delivery Method

13.3.7. Market Revenue and Volume Forecast, by End User

13.3.8. China

13.3.8.1. Market Revenue and Volume Forecast, by Type

13.3.8.2. Market Revenue and Volume Forecast, by Application

13.3.8.3. Market Revenue and Volume Forecast, by Synthesis Method

13.3.8.4. Market Revenue and Volume Forecast, by Delivery Method

13.3.9. Market Revenue and Volume Forecast, by End User

13.3.10. Japan

13.3.10.1. Market Revenue and Volume Forecast, by Type

13.3.10.2. Market Revenue and Volume Forecast, by Application

13.3.10.3. Market Revenue and Volume Forecast, by Synthesis Method

13.3.10.4. Market Revenue and Volume Forecast, by Delivery Method

13.3.10.5. Market Revenue and Volume Forecast, by End User

13.3.11. Rest of APAC

13.3.11.1. Market Revenue and Volume Forecast, by Type

13.3.11.2. Market Revenue and Volume Forecast, by Application

13.3.11.3. Market Revenue and Volume Forecast, by Synthesis Method

13.3.11.4. Market Revenue and Volume Forecast, by Delivery Method

13.3.11.5. Market Revenue and Volume Forecast, by End User

13.4. MEA

13.4.1. Market Revenue and Volume Forecast, by Type

13.4.2. Market Revenue and Volume Forecast, by Application

13.4.3. Market Revenue and Volume Forecast, by Synthesis Method

13.4.4. Market Revenue and Volume Forecast, by Delivery Method

13.4.5. Market Revenue and Volume Forecast, by End User

13.4.6. GCC

13.4.6.1. Market Revenue and Volume Forecast, by Type

13.4.6.2. Market Revenue and Volume Forecast, by Application

13.4.6.3. Market Revenue and Volume Forecast, by Synthesis Method

13.4.6.4. Market Revenue and Volume Forecast, by Delivery Method

13.4.7. Market Revenue and Volume Forecast, by End User

13.4.8. North Africa

13.4.8.1. Market Revenue and Volume Forecast, by Type

13.4.8.2. Market Revenue and Volume Forecast, by Application

13.4.8.3. Market Revenue and Volume Forecast, by Synthesis Method

13.4.8.4. Market Revenue and Volume Forecast, by Delivery Method

13.4.9. Market Revenue and Volume Forecast, by End User

13.4.10. South Africa

13.4.10.1. Market Revenue and Volume Forecast, by Type

13.4.10.2. Market Revenue and Volume Forecast, by Application

13.4.10.3. Market Revenue and Volume Forecast, by Synthesis Method

13.4.10.4. Market Revenue and Volume Forecast, by Delivery Method

13.4.10.5. Market Revenue and Volume Forecast, by End User

13.4.11. Rest of MEA

13.4.11.1. Market Revenue and Volume Forecast, by Type

13.4.11.2. Market Revenue and Volume Forecast, by Application

13.4.11.3. Market Revenue and Volume Forecast, by Synthesis Method

13.4.11.4. Market Revenue and Volume Forecast, by Delivery Method

13.4.11.5. Market Revenue and Volume Forecast, by End User

13.5. Latin America

13.5.1. Market Revenue and Volume Forecast, by Type

13.5.2. Market Revenue and Volume Forecast, by Application

13.5.3. Market Revenue and Volume Forecast, by Synthesis Method

13.5.4. Market Revenue and Volume Forecast, by Delivery Method

13.5.5. Market Revenue and Volume Forecast, by End User

13.5.6. Brazil

13.5.6.1. Market Revenue and Volume Forecast, by Type

13.5.6.2. Market Revenue and Volume Forecast, by Application

13.5.6.3. Market Revenue and Volume Forecast, by Synthesis Method

13.5.6.4. Market Revenue and Volume Forecast, by Delivery Method

13.5.7. Market Revenue and Volume Forecast, by End User

13.5.8. Rest of LATAM

13.5.8.1. Market Revenue and Volume Forecast, by Type

13.5.8.2. Market Revenue and Volume Forecast, by Application

13.5.8.3. Market Revenue and Volume Forecast, by Synthesis Method

13.5.8.4. Market Revenue and Volume Forecast, by Delivery Method

13.5.8.5. Market Revenue and Volume Forecast, by End User

Chapter 14. Company Profiles

14.1. SomaLogic Inc.

14.1.1. Company Overview

14.1.2. Product Offerings

14.1.3. Financial Performance

14.1.4. Recent Initiatives

14.2. Aptamer Group PLC

14.2.1. Company Overview

14.2.2. Product Offerings

14.2.3. Financial Performance

14.2.4. Recent Initiatives

14.3. NOXXON Pharma AG

14.3.1. Company Overview

14.3.2. Product Offerings

14.3.3. Financial Performance

14.3.4. Recent Initiatives

14.4. Base Pair Biotechnologies Inc.

14.4.1. Company Overview

14.4.2. Product Offerings

14.4.3. Financial Performance

14.4.4. Recent Initiatives

14.5. Aptamer Sciences Inc.

14.5.1. Company Overview

14.5.2. Product Offerings

14.5.3. Financial Performance

14.5.4. Recent Initiatives

14.6. AM Biotechnologies LLC

14.6.1. Company Overview

14.6.2. Product Offerings

14.6.3. Financial Performance

14.6.4. Recent Initiatives

14.7. NeoVentures Biotechnology Inc.

14.7.1. Company Overview

14.7.2. Product Offerings

14.7.3. Financial Performance

14.7.4. Recent Initiatives

14.8. TriLink BioTechnologies LLC

14.8.1. Company Overview

14.8.2. Product Offerings

14.8.3. Financial Performance

14.8.4. Recent Initiatives

14.9. Aptus Biotech S.L.

14.9.1. Company Overview

14.9.2. Product Offerings

14.9.3. Financial Performance

14.9.4. Recent Initiatives

14.10. Aptagen LLC

14.10.1. Company Overview

14.10.2. Product Offerings

14.10.3. Financial Performance

14.10.4. Recent Initiatives

Chapter 15. Research Methodology

15.1. Primary Research

15.2. Secondary Research

15.3. Assumptions

Chapter 16. Appendix

16.1. About Us

16.2. Glossary of Terms

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Frequently Asked Questions

The nucleic acid aptamers market size is expected to increase from USD 257.93 million in 2024 to USD 1,267.63 million by 2034.

The nucleic acid aptamers market is expected to grow at a compound annual growth rate (CAGR) of around 17.26% from 2025 to 2034.

The major players in the nucleic acid aptamers market include SomaLogic Inc., Aptamer Group PLC, NOXXON Pharma AG, Base Pair Biotechnologies Inc., Aptamer Sciences Inc., AM Biotechnologies LLC, NeoVentures Biotechnology Inc., TriLink BioTechnologies LLC, Aptus Biotech S.L., Aptagen LLC, Vivonics Inc., Aptamer Solutions Ltd., AuramerBio Ltd., Bio-Techne Corporation, Novaptech, IBA GmbH, ATDBio Ltd., Raptamer Discovery Group, LC Sciences LLC, and Integrated DNA Technologies (IDT).

The driving factors of the nucleic acid aptamers market are the increasing investments in research and development activities related to aptamers. The demand for targeted therapies has been increasing, driving innovation and development of nucleic acid aptamers, fueling the market growth.

North America region will lead the global nucleic acid aptamers market during the forecast period 2025 to 2034.

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