Penicillin G Acylase Market Size, Share, and Trends 2025 to 2034

The global penicillin G acylase market size is calculated at USD 158.39 million in 2025 and is forecasted to reach around USD 257.77 million by 2034, accelerating at a CAGR of 5.56% from 2025 to 2034. The Asia Pacific market size surpassed USD 60.02 million in 2024 and is expanding at a CAGR of 5.69% during the forecast period. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

Last Updated : August 2025  |  Report Code : 6628  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology  

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Penicillin G Acylase Market 

5.1. COVID-19 Landscape: Penicillin G Acylase Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Penicillin G Acylase Market, By Type

8.1. Penicillin G Acylase Market Revenue and Volume, by Type

8.1.1. Free Enzyme

8.1.1.1. Market Revenue and Volume Forecast

8.1.2. Immobilized Enzyme

8.1.2.1. Market Revenue and Volume Forecast

8.1.3. Others: Enzyme blends, recombinant PGA

8.1.3.1. Market Revenue and Volume Forecast

Chapter 9. Global Penicillin G Acylase Market, By Application

9.1. Penicillin G Acylase Market Revenue and Volume, by Application

9.1.1. β-Lactam Antibiotic Production

9.1.1.1. Market Revenue and Volume Forecast

9.1.2. Cephalosporin Derivatives

9.1.2.1. Market Revenue and Volume Forecast

9.1.3. Industrial Biocatalysis

9.1.3.1. Market Revenue and Volume Forecast

9.1.4. Research & Development

9.1.4.1. Market Revenue and Volume Forecast

9.1.5. Others: Specialty chemicals, biosensor applications

9.1.5.1. Market Revenue and Volume Forecast

Chapter 10. Global Penicillin G Acylase Market, By End-Use Industry 

10.1. Penicillin G Acylase Market Revenue and Volume, by End-Use Industry

10.1.1. Pharmaceutical Industry

10.1.1.1. Market Revenue and Volume Forecast

10.1.2. Biotechnology Companies

10.1.2.1. Market Revenue and Volume Forecast

10.1.3. Contract Manufacturing Organizations (CMOs)

10.1.3.1. Market Revenue and Volume Forecast

10.1.4. Research Institutes & Academic Labs

10.1.4.1. Market Revenue and Volume Forecast

10.1.5. Others: Specialty chemical manufacturers

10.1.5.1. Market Revenue and Volume Forecast

Chapter 11. Global Penicillin G Acylase Market, By Form

11.1. Penicillin G Acylase Market Revenue and Volume, by Form

11.1.1. Powder

11.1.1.1. Market Revenue and Volume Forecast

11.1.2. Liquid

11.1.2.1. Market Revenue and Volume Forecast

11.1.3. Others: Lyophilized formulations

11.1.3.1. Market Revenue and Volume Forecast

Chapter 12. Global Penicillin G Acylase Market, By Production Method

12.1. Penicillin G Acylase Market Revenue and Volume, by Production Method

12.1.1. Microbial Fermentation

12.1.1.1. Market Revenue and Volume Forecast

12.1.2. Recombinant Technology

12.1.2.1. Market Revenue and Volume Forecast

12.1.3. Others: Enzyme immobilization techniques

12.1.3.1. Market Revenue and Volume Forecast

Chapter 13. Global Penicillin G Acylase Market, Regional Estimates and Trend Forecast

13.1. North America

13.1.1. Market Revenue and Volume Forecast, by Type

13.1.2. Market Revenue and Volume Forecast, by Application

13.1.3. Market Revenue and Volume Forecast, by End-Use Industry

13.1.4. Market Revenue and Volume Forecast, by Form

13.1.5. Market Revenue and Volume Forecast, by Production Method

13.1.6. U.S.

13.1.6.1. Market Revenue and Volume Forecast, by Type

13.1.6.2. Market Revenue and Volume Forecast, by Application

13.1.6.3. Market Revenue and Volume Forecast, by End-Use Industry

13.1.6.4. Market Revenue and Volume Forecast, by Form

13.1.6.5. Market Revenue and Volume Forecast, by Production Method  

13.1.7. Rest of North America

13.1.7.1. Market Revenue and Volume Forecast, by Type

13.1.7.2. Market Revenue and Volume Forecast, by Application

13.1.7.3. Market Revenue and Volume Forecast, by End-Use Industry

13.1.7.4. Market Revenue and Volume Forecast, by Form

13.1.7.5. Market Revenue and Volume Forecast, by Production Method

13.2. Europe

13.2.1. Market Revenue and Volume Forecast, by Type

13.2.2. Market Revenue and Volume Forecast, by Application

13.2.3. Market Revenue and Volume Forecast, by End-Use Industry

13.2.4. Market Revenue and Volume Forecast, by Form  

13.2.5. Market Revenue and Volume Forecast, by Production Method  

13.2.6. UK

13.2.6.1. Market Revenue and Volume Forecast, by Type

13.2.6.2. Market Revenue and Volume Forecast, by Application

13.2.6.3. Market Revenue and Volume Forecast, by End-Use Industry

13.2.7. Market Revenue and Volume Forecast, by Form  

13.2.8. Market Revenue and Volume Forecast, by Production Method  

13.2.9. Germany

13.2.9.1. Market Revenue and Volume Forecast, by Type

13.2.9.2. Market Revenue and Volume Forecast, by Application

13.2.9.3. Market Revenue and Volume Forecast, by End-Use Industry

13.2.10. Market Revenue and Volume Forecast, by Form

13.2.11. Market Revenue and Volume Forecast, by Production Method

13.2.12. France

13.2.12.1. Market Revenue and Volume Forecast, by Type

13.2.12.2. Market Revenue and Volume Forecast, by Application

13.2.12.3. Market Revenue and Volume Forecast, by End-Use Industry

13.2.12.4. Market Revenue and Volume Forecast, by Form

13.2.13. Market Revenue and Volume Forecast, by Production Method

13.2.14. Rest of Europe

13.2.14.1. Market Revenue and Volume Forecast, by Type

13.2.14.2. Market Revenue and Volume Forecast, by Application

13.2.14.3. Market Revenue and Volume Forecast, by End-Use Industry

13.2.14.4. Market Revenue and Volume Forecast, by Form

13.2.15. Market Revenue and Volume Forecast, by Production Method

13.3. APAC

13.3.1. Market Revenue and Volume Forecast, by Type

13.3.2. Market Revenue and Volume Forecast, by Application

13.3.3. Market Revenue and Volume Forecast, by End-Use Industry

13.3.4. Market Revenue and Volume Forecast, by Form

13.3.5. Market Revenue and Volume Forecast, by Production Method

13.3.6. India

13.3.6.1. Market Revenue and Volume Forecast, by Type

13.3.6.2. Market Revenue and Volume Forecast, by Application

13.3.6.3. Market Revenue and Volume Forecast, by End-Use Industry

13.3.6.4. Market Revenue and Volume Forecast, by Form

13.3.7. Market Revenue and Volume Forecast, by Production Method

13.3.8. China

13.3.8.1. Market Revenue and Volume Forecast, by Type

13.3.8.2. Market Revenue and Volume Forecast, by Application

13.3.8.3. Market Revenue and Volume Forecast, by End-Use Industry

13.3.8.4. Market Revenue and Volume Forecast, by Form

13.3.9. Market Revenue and Volume Forecast, by Production Method

13.3.10. Japan

13.3.10.1. Market Revenue and Volume Forecast, by Type

13.3.10.2. Market Revenue and Volume Forecast, by Application

13.3.10.3. Market Revenue and Volume Forecast, by End-Use Industry

13.3.10.4. Market Revenue and Volume Forecast, by Form

13.3.10.5. Market Revenue and Volume Forecast, by Production Method

13.3.11. Rest of APAC

13.3.11.1. Market Revenue and Volume Forecast, by Type

13.3.11.2. Market Revenue and Volume Forecast, by Application

13.3.11.3. Market Revenue and Volume Forecast, by End-Use Industry

13.3.11.4. Market Revenue and Volume Forecast, by Form

13.3.11.5. Market Revenue and Volume Forecast, by Production Method

13.4. MEA

13.4.1. Market Revenue and Volume Forecast, by Type

13.4.2. Market Revenue and Volume Forecast, by Application

13.4.3. Market Revenue and Volume Forecast, by End-Use Industry

13.4.4. Market Revenue and Volume Forecast, by Form

13.4.5. Market Revenue and Volume Forecast, by Production Method

13.4.6. GCC

13.4.6.1. Market Revenue and Volume Forecast, by Type

13.4.6.2. Market Revenue and Volume Forecast, by Application

13.4.6.3. Market Revenue and Volume Forecast, by End-Use Industry

13.4.6.4. Market Revenue and Volume Forecast, by Form

13.4.7. Market Revenue and Volume Forecast, by Production Method

13.4.8. North Africa

13.4.8.1. Market Revenue and Volume Forecast, by Type

13.4.8.2. Market Revenue and Volume Forecast, by Application

13.4.8.3. Market Revenue and Volume Forecast, by End-Use Industry

13.4.8.4. Market Revenue and Volume Forecast, by Form

13.4.9. Market Revenue and Volume Forecast, by Production Method

13.4.10. South Africa

13.4.10.1. Market Revenue and Volume Forecast, by Type

13.4.10.2. Market Revenue and Volume Forecast, by Application

13.4.10.3. Market Revenue and Volume Forecast, by End-Use Industry

13.4.10.4. Market Revenue and Volume Forecast, by Form

13.4.10.5. Market Revenue and Volume Forecast, by Production Method

13.4.11. Rest of MEA

13.4.11.1. Market Revenue and Volume Forecast, by Type

13.4.11.2. Market Revenue and Volume Forecast, by Application

13.4.11.3. Market Revenue and Volume Forecast, by End-Use Industry

13.4.11.4. Market Revenue and Volume Forecast, by Form

13.4.11.5. Market Revenue and Volume Forecast, by Production Method

13.5. Latin America

13.5.1. Market Revenue and Volume Forecast, by Type

13.5.2. Market Revenue and Volume Forecast, by Application

13.5.3. Market Revenue and Volume Forecast, by End-Use Industry

13.5.4. Market Revenue and Volume Forecast, by Form

13.5.5. Market Revenue and Volume Forecast, by Production Method

13.5.6. Brazil

13.5.6.1. Market Revenue and Volume Forecast, by Type

13.5.6.2. Market Revenue and Volume Forecast, by Application

13.5.6.3. Market Revenue and Volume Forecast, by End-Use Industry

13.5.6.4. Market Revenue and Volume Forecast, by Form

13.5.7. Market Revenue and Volume Forecast, by Production Method

13.5.8. Rest of LATAM

13.5.8.1. Market Revenue and Volume Forecast, by Type

13.5.8.2. Market Revenue and Volume Forecast, by Application

13.5.8.3. Market Revenue and Volume Forecast, by End-Use Industry

13.5.8.4. Market Revenue and Volume Forecast, by Form

13.5.8.5. Market Revenue and Volume Forecast, by Production Method

Chapter 14. Company Profiles

14.1. Novozymes A/S

14.1.1. Company Overview

14.1.2. Product Offerings

14.1.3. Financial Performance

14.1.4. Recent Initiatives

14.2. DSM N.V.

14.2.1. Company Overview

14.2.2. Product Offerings

14.2.3. Financial Performance

14.2.4. Recent Initiatives

14.3. Amano Enzyme Inc.

14.3.1. Company Overview

14.3.2. Product Offerings

14.3.3. Financial Performance

14.3.4. Recent Initiatives

14.4. Takeda Pharmaceutical Company Limited

14.4.1. Company Overview

14.4.2. Product Offerings

14.4.3. Financial Performance

14.4.4. Recent Initiatives

14.5. Meiji Seika Pharma Co., Ltd.

14.5.1. Company Overview

14.5.2. Product Offerings

14.5.3. Financial Performance

14.5.4. Recent Initiatives

14.6. Codexis, Inc.

14.6.1. Company Overview

14.6.2. Product Offerings

14.6.3. Financial Performance

14.6.4. Recent Initiatives

14.7. Chr. Hansen Holding A/S

14.7.1. Company Overview

14.7.2. Product Offerings

14.7.3. Financial Performance

14.7.4. Recent Initiatives

14.8. Gist-Brocades (now part of DSM)

14.8.1. Company Overview

14.8.2. Product Offerings

14.8.3. Financial Performance

14.8.4. Recent Initiatives

14.9. Henan Lingrui Biochemical Co., Ltd.

14.9.1. Company Overview

14.9.2. Product Offerings

14.9.3. Financial Performance

14.9.4. Recent Initiatives

14.10. Advanced Enzymes Technologies Ltd.

14.10.1. Company Overview

14.10.2. Product Offerings

14.10.3. Financial Performance

14.10.4. Recent Initiatives

Chapter 15. Research Methodology

15.1. Primary Research

15.2. Secondary Research

15.3. Assumptions

Chapter 16. Appendix

16.1. About Us

16.2. Glossary of Terms

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Frequently Asked Questions

The penicillin G acylase market size is expected to increase from USD 150.05 million in 2024 to USD 257.77 million by 2034.

The penicillin G acylase market is expected to grow at a compound annual growth rate (CAGR) of around 5.56% from 2025 to 2034.

The major players in the penicillin G acylase market include Novozymes A/S, DSM N.V., Amano Enzyme Inc., Takeda Pharmaceutical Company Limited, Meiji Seika Pharma Co., Ltd., Codexis, Inc., Chr. Hansen Holding A/S, Gist-Brocades (now part of DSM), Henan Lingrui Biochemical Co., Ltd., Advanced Enzymes Technologies Ltd., Jiangsu Meilin Pharmaceutical Co., Ltd., Beijing Anno Pharmaceutical Co., Ltd., BioCatalytics Inc., Shanghai Enzyme Co., Ltd., Kyowa Hakko Bio Co., Ltd., Shandong Longda Biochemical Co., Ltd., Xiamen Innovax Biotech Co., Ltd., Biocon Limited, AB Enzymes GmbH, and Enzymicals AG.

The driving factors of the penicillin G acylase market are the growing demand for semi-synthetic antibiotics, rapid advancements in enzyme immobilization technologies, growing demand for enzyme-based manufacturing processes, and increasing popularity of sustainable production methods are expected to drive the growth of the global market

Asia Pacific region will lead the global penicillin G acylase market during the forecast period 2025 to 2034.

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