Oncolytic Virus-Based Gene Therapy Market Size, Share, and Trends 2025 to 2034

Oncolytic Virus-Based Gene Therapy Market (By Virus Type: Herpes Simplex Virus (HSV), Adenovirus, Vaccinia Virus, Newcastle Disease Virus (NDV), Reovirus, Measles Virus; By Delivery Route: Intratumoral, Intravenous, Intraperitoneal, Intrathecal, Subcutaneous; By Cancer Type: Melanoma, Glioblastoma, Head and Neck Cancer, Breast Cancer, Lung Cancer, Prostate Cancer, Pancreatic Cancer, Liver Cancer, Bladder Cancer; By End-User: Pharmaceutical & Biotechnology Companies, Contract Development and Manufacturing Organizations (CDMOs), Academic & Research Institutes;) - Global Industry Analysis, Size, Trends, Leading Companies, Regional Outlook, and Forecast 2025 to 2034

Last Updated : October 2025  |  Report Code : 6975  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Oncolytic Virus-Based Gene Therapy Market 

5.1. COVID-19 Landscape: Oncolytic Virus-Based Gene Therapy Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Oncolytic Virus-Based Gene Therapy Market, By Virus Type

8.1. Oncolytic Virus-Based Gene Therapy Market, by Virus Type

8.1.1. Herpes Simplex Virus (HSV)

8.1.1.1. Market Revenue and Forecast

8.1.2. Adenovirus

8.1.2.1. Market Revenue and Forecast

8.1.3. Vaccinia Virus

8.1.3.1. Market Revenue and Forecast

8.1.4. Newcastle Disease Virus (NDV)

8.1.4.1. Market Revenue and Forecast

8.1.5. Reovirus

8.1.5.1. Market Revenue and Forecast

8.1.6. Measles Virus

8.1.6.1. Market Revenue and Forecast

Chapter 9. Global Oncolytic Virus-Based Gene Therapy Market, By Delivery Route

9.1. Oncolytic Virus-Based Gene Therapy Market, by Delivery Route

9.1.1. Intratumoral

9.1.1.1. Market Revenue and Forecast

9.1.2. Intravenous

9.1.2.1. Market Revenue and Forecast

9.1.3. Intraperitoneal

9.1.3.1. Market Revenue and Forecast

9.1.4. Intrathecal

9.1.4.1. Market Revenue and Forecast

9.1.5. Subcutaneous

9.1.5.1. Market Revenue and Forecast

Chapter 10. Global Oncolytic Virus-Based Gene Therapy Market, By Cancer Type 

10.1. Oncolytic Virus-Based Gene Therapy Market, by Cancer Type

10.1.1. Melanoma

10.1.1.1. Market Revenue and Forecast

10.1.2. Glioblastoma

10.1.2.1. Market Revenue and Forecast

10.1.3. Head and Neck Cancer

10.1.3.1. Market Revenue and Forecast

10.1.4. Head and Neck Cancer

10.1.4.1. Market Revenue and Forecast

10.1.5. Lung Cancer

10.1.5.1. Market Revenue and Forecast

10.1.6. Prostate Cancer

10.1.6.1. Market Revenue and Forecast

10.1.7. Pancreatic Cancer

10.1.7.1. Market Revenue and Forecast

10.1.8. Liver Cancer

10.1.8.1. Market Revenue and Forecast

Chapter 11. Global Oncolytic Virus-Based Gene Therapy Market, By End-User 

11.1. Oncolytic Virus-Based Gene Therapy Market, by End-User

11.1.1. Pharmaceutical & Biotechnology Companies

11.1.1.1. Market Revenue and Forecast

11.1.2. Contract Development and Manufacturing Organizations (CDMOs)

11.1.2.1. Market Revenue and Forecast

11.1.3. Academic & Research Institutes

11.1.3.1. Market Revenue and Forecast

Chapter 12. Global Oncolytic Virus-Based Gene Therapy Market, Regional Estimates and Trend Forecast

12.1. North America

12.1.1. Market Revenue and Forecast, by Virus Type

12.1.2. Market Revenue and Forecast, by Delivery Route  

12.1.3. Market Revenue and Forecast, by Cancer Type

12.1.4. Market Revenue and Forecast, by End-User

12.1.5. U.S.

12.1.5.1. Market Revenue and Forecast, by Virus Type

12.1.5.2. Market Revenue and Forecast, by Delivery Route  

12.1.5.3. Market Revenue and Forecast, by Cancer Type

12.1.5.4. Market Revenue and Forecast, by End-User

12.1.6. Rest of North America

12.1.6.1. Market Revenue and Forecast, by Virus Type

12.1.6.2. Market Revenue and Forecast, by Delivery Route  

12.1.6.3. Market Revenue and Forecast, by Cancer Type

12.1.6.4. Market Revenue and Forecast, by End-User

12.2. Europe

12.2.1. Market Revenue and Forecast, by Virus Type

12.2.2. Market Revenue and Forecast, by Delivery Route  

12.2.3. Market Revenue and Forecast, by Cancer Type

12.2.4. Market Revenue and Forecast, by End-User

12.2.5. UK

12.2.5.1. Market Revenue and Forecast, by Virus Type

12.2.5.2. Market Revenue and Forecast, by Delivery Route  

12.2.5.3. Market Revenue and Forecast, by Cancer Type

12.2.5.4. Market Revenue and Forecast, by End-User

12.2.6. Germany

12.2.6.1. Market Revenue and Forecast, by Virus Type

12.2.6.2. Market Revenue and Forecast, by Delivery Route  

12.2.6.3. Market Revenue and Forecast, by Cancer Type

12.2.6.4. Market Revenue and Forecast, by End-User

12.2.7. France

12.2.7.1. Market Revenue and Forecast, by Virus Type

12.2.7.2. Market Revenue and Forecast, by Delivery Route  

12.2.7.3. Market Revenue and Forecast, by Cancer Type

12.2.7.4. Market Revenue and Forecast, by End-User

12.2.8. Rest of Europe

12.2.8.1. Market Revenue and Forecast, by Virus Type

12.2.8.2. Market Revenue and Forecast, by Delivery Route  

12.2.8.3. Market Revenue and Forecast, by Cancer Type

12.2.8.4. Market Revenue and Forecast, by End-User

12.3. APAC

12.3.1. Market Revenue and Forecast, by Virus Type

12.3.2. Market Revenue and Forecast, by Delivery Route  

12.3.3. Market Revenue and Forecast, by Cancer Type

12.3.4. Market Revenue and Forecast, by End-User

12.3.5. India

12.3.5.1. Market Revenue and Forecast, by Virus Type

12.3.5.2. Market Revenue and Forecast, by Delivery Route  

12.3.5.3. Market Revenue and Forecast, by Cancer Type

12.3.5.4. Market Revenue and Forecast, by End-User

12.3.6. China

12.3.6.1. Market Revenue and Forecast, by Virus Type

12.3.6.2. Market Revenue and Forecast, by Delivery Route  

12.3.6.3. Market Revenue and Forecast, by Cancer Type

12.3.6.4. Market Revenue and Forecast, by End-User

12.3.7. Japan

12.3.7.1. Market Revenue and Forecast, by Virus Type

12.3.7.2. Market Revenue and Forecast, by Delivery Route  

12.3.7.3. Market Revenue and Forecast, by Cancer Type

12.3.7.4. Market Revenue and Forecast, by End-User

12.3.8. Rest of APAC

12.3.8.1. Market Revenue and Forecast, by Virus Type

12.3.8.2. Market Revenue and Forecast, by Delivery Route  

12.3.8.3. Market Revenue and Forecast, by Cancer Type

12.3.8.4. Market Revenue and Forecast, by End-User

12.4. MEA

12.4.1. Market Revenue and Forecast, by Virus Type

12.4.2. Market Revenue and Forecast, by Delivery Route  

12.4.3. Market Revenue and Forecast, by Cancer Type

12.4.4. Market Revenue and Forecast, by End-User

12.4.5. GCC

12.4.5.1. Market Revenue and Forecast, by Virus Type

12.4.5.2. Market Revenue and Forecast, by Delivery Route  

12.4.5.3. Market Revenue and Forecast, by Cancer Type

12.4.5.4. Market Revenue and Forecast, by End-User

12.4.6. North Africa

12.4.6.1. Market Revenue and Forecast, by Virus Type

12.4.6.2. Market Revenue and Forecast, by Delivery Route  

12.4.6.3. Market Revenue and Forecast, by Cancer Type

12.4.6.4. Market Revenue and Forecast, by End-User

12.4.7. South Africa

12.4.7.1. Market Revenue and Forecast, by Virus Type

12.4.7.2. Market Revenue and Forecast, by Delivery Route  

12.4.7.3. Market Revenue and Forecast, by Cancer Type

12.4.7.4. Market Revenue and Forecast, by End-User

12.4.8. Rest of MEA

12.4.8.1. Market Revenue and Forecast, by Virus Type

12.4.8.2. Market Revenue and Forecast, by Delivery Route  

12.4.8.3. Market Revenue and Forecast, by Cancer Type

12.4.8.4. Market Revenue and Forecast, by End-User

12.5. Latin America

12.5.1. Market Revenue and Forecast, by Virus Type

12.5.2. Market Revenue and Forecast, by Delivery Route  

12.5.3. Market Revenue and Forecast, by Cancer Type

12.5.4. Market Revenue and Forecast, by End-User

12.5.5. Brazil

12.5.5.1. Market Revenue and Forecast, by Virus Type

12.5.5.2. Market Revenue and Forecast, by Delivery Route  

12.5.5.3. Market Revenue and Forecast, by Cancer Type

12.5.5.4. Market Revenue and Forecast, by End-User

12.5.6. Rest of LATAM

12.5.6.1. Market Revenue and Forecast, by Virus Type

12.5.6.2. Market Revenue and Forecast, by Delivery Route  

12.5.6.3. Market Revenue and Forecast, by Cancer Type

12.5.6.4. Market Revenue and Forecast, by End-User

Chapter 13. Company Profiles

13.1. Sorrento Therapeutics, Inc.

13.1.1. Company Overview

13.1.2. Product Offerings

13.1.3. Financial Performance

13.1.4. Recent Initiatives

13.2. Amgen, Inc.

13.2.1. Company Overview

13.2.2. Product Offerings

13.2.3. Financial Performance

13.2.4. Recent Initiatives

13.3. Replimune Group, Inc.

13.3.1. Company Overview

13.3.2. Product Offerings

13.3.3. Financial Performance

13.3.4. Recent Initiatives

13.4. Oncolytics Biotech, Inc.

13.4.1. Company Overview

13.4.2. Product Offerings

13.4.3. Financial Performance

13.4.4. Recent Initiatives

13.5. PsiOxus Therapeutics Ltd.

13.5.1. Company Overview

13.5.2. Product Offerings

13.5.3. Financial Performance

13.5.4. Recent Initiatives

13.6. Transgene SA

13.6.1. Company Overview

13.6.2. Product Offerings

13.6.3. Financial Performance

13.6.4. Recent Initiatives

13.7. SillaJen, Inc.

13.7.1. Company Overview

13.7.2. Product Offerings

13.7.3. Financial Performance

13.7.4. Recent Initiatives

13.8. Genelux Corporation

13.8.1. Company Overview

13.8.2. Product Offerings

13.8.3. Financial Performance

13.8.4. Recent Initiatives

13.9. Shanghai Sunway Biotech Co. Ltd.

13.9.1. Company Overview

13.9.2. Product Offerings

13.9.3. Financial Performance

13.9.4. Recent Initiatives

13.10. Takara Bio, Inc.

13.10.1. Company Overview

13.10.2. Product Offerings

13.10.3. Financial Performance

13.10.4. Recent Initiatives

Chapter 14. Research Methodology

14.1. Primary Research

14.2. Secondary Research

14.3. Assumptions

Chapter 15. Appendix

15.1. About Us

15.2. Glossary of Terms

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Frequently Asked Questions

The major players in the oncolytic virus-based gene therapy market include Takara Bio, Inc., Shanghai Sunway Biotech Co. Ltd., Genelux Corporation, Sorrento Therapeutics, Inc, PsiOxus Therapeutics Ltd. Transgene SA, SillaJen, Inc., Amgen, Inc.. and Replimune Group, Inc.

The driving factors of the oncolytic virus-based gene therapy market are the rising incidence of cancer, the increasing demand for innovative cancer treatments, and the unique dual mechanism of action of the oncolytic virus that both destroys tumors and stimulastes the immune system.

North America region will lead the global oncolytic virus-based gene therapy market during the forecast period 2025 to 2034.

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