Circulating Tumor DNA (ctDNA) Market Size, Share, and Trends 2025 to 2034

Circulating Tumor DNA (ctDNA) Market (By Technology: Next-Generation Sequencing, PCR-based Assays, Digital PCR: By Application; Cancer Diagnosis and Screening, Minimal Residual Disease (MRD) Monitoring, Treatment Monitoring, By Sample Type: Blood, Urine, Others; By End-User: Clinical Laboratories & Diagnostic Centers, Biopharma Companies, Hospitals, Research Institutions) - Global Industry Analysis, Size, Trends, Leading Companies, Regional Outlook, and Forecast 2025 to 2034

Last Updated : October 2025  |  Report Code : 7038  |  Category : Healthcare  |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Circulating Tumor DNA (ctDNA) Market 

5.1. COVID-19 Landscape: Circulating Tumor DNA (ctDNA) Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Circulating Tumor DNA (ctDNA) Market, By Technology

8.1. Circulating Tumor DNA (ctDNA) Market, by Technology

8.1.1. Next-Generation Sequencing (NGS)

8.1.1.1. Market Revenue and Forecast

8.1.2. PCR-based Assays

8.1.2.1. Market Revenue and Forecast

8.1.3. Digital PCR (dPCR)

8.1.3.1. Market Revenue and Forecast

Chapter 9. Global Circulating Tumor DNA (ctDNA) Market, By Application

9.1. Circulating Tumor DNA (ctDNA) Market, by Application

9.1.1. Cancer Diagnosis and Screening

9.1.1.1. Market Revenue and Forecast

9.1.2. Treatment Monitoring

9.1.2.1. Market Revenue and Forecast

Chapter 10. Global Circulating Tumor DNA (ctDNA) Market, By Sample Type 

10.1. Circulating Tumor DNA (ctDNA) Market, by Sample Type

10.1.1. Blood

10.1.1.1. Market Revenue and Forecast

10.1.2. Urine

10.1.2.1. Market Revenue and Forecast

10.1.3. Others (Cerebrospinal Fluid, etc.)

10.1.3.1. Market Revenue and Forecast

Chapter 11. Global Circulating Tumor DNA (ctDNA) Market, By End-User 

11.1. Circulating Tumor DNA (ctDNA) Market, by End-User

11.1.1. Clinical Laboratories & Diagnostic Centers

11.1.1.1. Market Revenue and Forecast

11.1.2. Biopharma Companies

11.1.2.1. Market Revenue and Forecast

11.1.3. Hospitals

11.1.3.1. Market Revenue and Forecast

11.1.4. Research Institutions

11.1.4.1. Market Revenue and Forecast

Chapter 12. Global Circulating Tumor DNA (ctDNA) Market, Regional Estimates and Trend Forecast

12.1. North America

12.1.1. Market Revenue and Forecast, by Technology

12.1.2. Market Revenue and Forecast, by Application

12.1.3. Market Revenue and Forecast, by Sample Type

12.1.4. Market Revenue and Forecast, by End-User

12.1.5. U.S.

12.1.5.1. Market Revenue and Forecast, by Technology

12.1.5.2. Market Revenue and Forecast, by Application

12.1.5.3. Market Revenue and Forecast, by Sample Type

12.1.5.4. Market Revenue and Forecast, by End-User

12.1.6. Rest of North America

12.1.6.1. Market Revenue and Forecast, by Technology

12.1.6.2. Market Revenue and Forecast, by Application

12.1.6.3. Market Revenue and Forecast, by Sample Type

12.1.6.4. Market Revenue and Forecast, by End-User

12.2. Europe

12.2.1. Market Revenue and Forecast, by Technology

12.2.2. Market Revenue and Forecast, by Application

12.2.3. Market Revenue and Forecast, by Sample Type

12.2.4. Market Revenue and Forecast, by End-User

12.2.5. UK

12.2.5.1. Market Revenue and Forecast, by Technology

12.2.5.2. Market Revenue and Forecast, by Application

12.2.5.3. Market Revenue and Forecast, by Sample Type

12.2.5.4. Market Revenue and Forecast, by End-User

12.2.6. Germany

12.2.6.1. Market Revenue and Forecast, by Technology

12.2.6.2. Market Revenue and Forecast, by Application

12.2.6.3. Market Revenue and Forecast, by Sample Type

12.2.6.4. Market Revenue and Forecast, by End-User

12.2.7. France

12.2.7.1. Market Revenue and Forecast, by Technology

12.2.7.2. Market Revenue and Forecast, by Application

12.2.7.3. Market Revenue and Forecast, by Sample Type

12.2.7.4. Market Revenue and Forecast, by End-User

12.2.8. Rest of Europe

12.2.8.1. Market Revenue and Forecast, by Technology

12.2.8.2. Market Revenue and Forecast, by Application

12.2.8.3. Market Revenue and Forecast, by Sample Type

12.2.8.4. Market Revenue and Forecast, by End-User

12.3. APAC

12.3.1. Market Revenue and Forecast, by Technology

12.3.2. Market Revenue and Forecast, by Application

12.3.3. Market Revenue and Forecast, by Sample Type

12.3.4. Market Revenue and Forecast, by End-User

12.3.5. India

12.3.5.1. Market Revenue and Forecast, by Technology

12.3.5.2. Market Revenue and Forecast, by Application

12.3.5.3. Market Revenue and Forecast, by Sample Type

12.3.5.4. Market Revenue and Forecast, by End-User

12.3.6. China

12.3.6.1. Market Revenue and Forecast, by Technology

12.3.6.2. Market Revenue and Forecast, by Application

12.3.6.3. Market Revenue and Forecast, by Sample Type

12.3.6.4. Market Revenue and Forecast, by End-User

12.3.7. Japan

12.3.7.1. Market Revenue and Forecast, by Technology

12.3.7.2. Market Revenue and Forecast, by Application

12.3.7.3. Market Revenue and Forecast, by Sample Type

12.3.7.4. Market Revenue and Forecast, by End-User

12.3.8. Rest of APAC

12.3.8.1. Market Revenue and Forecast, by Technology

12.3.8.2. Market Revenue and Forecast, by Application

12.3.8.3. Market Revenue and Forecast, by Sample Type

12.3.8.4. Market Revenue and Forecast, by End-User

12.4. MEA

12.4.1. Market Revenue and Forecast, by Technology

12.4.2. Market Revenue and Forecast, by Application

12.4.3. Market Revenue and Forecast, by Sample Type

12.4.4. Market Revenue and Forecast, by End-User

12.4.5. GCC

12.4.5.1. Market Revenue and Forecast, by Technology

12.4.5.2. Market Revenue and Forecast, by Application

12.4.5.3. Market Revenue and Forecast, by Sample Type

12.4.5.4. Market Revenue and Forecast, by End-User

12.4.6. North Africa

12.4.6.1. Market Revenue and Forecast, by Technology

12.4.6.2. Market Revenue and Forecast, by Application

12.4.6.3. Market Revenue and Forecast, by Sample Type

12.4.6.4. Market Revenue and Forecast, by End-User

12.4.7. South Africa

12.4.7.1. Market Revenue and Forecast, by Technology

12.4.7.2. Market Revenue and Forecast, by Application

12.4.7.3. Market Revenue and Forecast, by Sample Type

12.4.7.4. Market Revenue and Forecast, by End-User

12.4.8. Rest of MEA

12.4.8.1. Market Revenue and Forecast, by Technology

12.4.8.2. Market Revenue and Forecast, by Application

12.4.8.3. Market Revenue and Forecast, by Sample Type

12.4.8.4. Market Revenue and Forecast, by End-User

12.5. Latin America

12.5.1. Market Revenue and Forecast, by Technology

12.5.2. Market Revenue and Forecast, by Application

12.5.3. Market Revenue and Forecast, by Sample Type

12.5.4. Market Revenue and Forecast, by End-User

12.5.5. Brazil

12.5.5.1. Market Revenue and Forecast, by Technology

12.5.5.2. Market Revenue and Forecast, by Application

12.5.5.3. Market Revenue and Forecast, by Sample Type

12.5.5.4. Market Revenue and Forecast, by End-User

12.5.6. Rest of LATAM

12.5.6.1. Market Revenue and Forecast, by Technology

12.5.6.2. Market Revenue and Forecast, by Application

12.5.6.3. Market Revenue and Forecast, by Sample Type

12.5.6.4. Market Revenue and Forecast, by End-User

Chapter 13. Company Profiles

13.1. Guardant Health

13.1.1. Company Overview

13.1.2. Product Offerings

13.1.3. Financial Performance

13.1.4. Recent Initiatives

13.2. Roche Diagnostics

13.2.1. Company Overview

13.2.2. Product Offerings

13.2.3. Financial Performance

13.2.4. Recent Initiatives

13.3. Thermo Fisher Scientific

13.3.1. Company Overview

13.3.2. Product Offerings

13.3.3. Financial Performance

13.3.4. Recent Initiatives

13.4. Natera

13.4.1. Company Overview

13.4.2. Product Offerings

13.4.3. Financial Performance

13.4.4. Recent Initiatives

13.5. Guardant Health

13.5.1. Company Overview

13.5.2. Product Offerings

13.5.3. Financial Performance

13.5.4. Recent Initiatives

13.6. QIAGEN

13.6.1. Company Overview

13.6.2. Product Offerings

13.6.3. Financial Performance

13.6.4. Recent Initiatives

13.7. Foundation Medicine

13.7.1. Company Overview

13.7.2. Product Offerings

13.7.3. Financial Performance

13.7.4. Recent Initiatives

13.8. Bio Rad Laboratories

13.8.1. Company Overview

13.8.2. Product Offerings

13.8.3. Financial Performance

13.8.4. Recent Initiatives

13.9. Sysmex Corporation

13.9.1. Company Overview

13.9.2. Product Offerings

13.9.3. Financial Performance

13.9.4. Recent Initiatives

13.10. GRAIL

13.10.1. Company Overview

13.10.2. Product Offerings

13.10.3. Financial Performance

13.10.4. Recent Initiatives

Chapter 14. Research Methodology

14.1. Primary Research

14.2. Secondary Research

14.3. Assumptions

Chapter 15. Appendix

15.1. About Us

15.2. Glossary of Terms

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Frequently Asked Questions

The circulating tumor DNA (ctDNA) market size is expected to increase from USD 7.96 billion in 2025 to USD 27.67 billion by 2034.

The circulating tumor DNA (ctDNA) market is expected to grow at a compound annual growth rate (CAGR) of around 14.85% from 2025 to 2034.

The major players in the circulating tumor DNA (ctDNA) market include Guardant Health, Roche Diagnostics, Illumina, Thermo Fisher Scientific, Natera, Guardant Health, QIAGEN, Foundation Medicine, Bio Rad Laboratories, Sysmex Corporation, and GRAIL

The driving factors of the circulating tumor DNA (ctDNA) market are the growth in precision oncology, demand for targeted therapies, and advancements in next-generation sequencing (NGS) technology are driving the growth of the circulating tumor DNA (ctDNA) market.

North America region will lead the global circulating tumor DNA (ctDNA) market during the forecast period 2025 to 2034.

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