Small Interfering RNA (siRNA) Therapeutics Market Size, Share, and Trends 2026 to 2035

Small Interfering RNA (siRNA) Therapeutics Market (By Application: Cancer, Neurological Disorders, Cardiovascular Diseases, Ophthalmic Diseases, Infectious Diseases, Other Therapeutic Applications; By Delivery System: Liposomes, Polymers, Lipid Nanoparticles, Viral Vectors, Other Delivery Systems; By Synthetic Route: Chemical Synthesis, Biotechnology, Other Synthetic Routes; By Mechanism of Action: Gene Editing, Gene Silencing, MicroRNA Mimics, Others (e.g., siRNA-mediated mRNA decay)) - Global Industry Analysis, Size, Trends, Leading Companies, Regional Outlook, and Forecast 2026 to 2035

Last Updated : 24 Feb 2026  |  Report Code : 7856  |  Category : Healthcare   |  Format : PDF / PPT / Excel

Chapter 1. Introduction

1.1. Research Objective

1.2. Scope of the Study

1.3. Definition

Chapter 2. Research Methodology

2.1. Research Approach

2.2. Data Sources

2.3. Assumptions & Limitations

Chapter 3. Executive Summary

3.1. Market Snapshot

Chapter 4. Market Variables and Scope 

4.1. Introduction

4.2. Market Classification and Scope

4.3. Industry Value Chain Analysis

4.3.1. Raw Material Procurement Analysis 

4.3.2. Sales and Distribution Channel Analysis

4.3.3. Downstream Buyer Analysis

Chapter 5. COVID 19 Impact on Small Interfering RNA (siRNA) Therapeutics Market 

5.1. COVID-19 Landscape: Small Interfering RNA (siRNA) Therapeutics Industry Impact

5.2. COVID 19 - Impact Assessment for the Industry

5.3. COVID 19 Impact: Global Major Government Policy

5.4. Market Trends and Opportunities in the COVID-19 Landscape

6.1. Market Dynamics

6.1.1. Market Drivers

6.1.2. Market Restraints

6.1.3. Market Opportunities

6.2. Porter’s Five Forces Analysis

6.2.1. Bargaining power of suppliers

6.2.2. Bargaining power of buyers

6.2.3. Threat of substitute

6.2.4. Threat of new entrants

6.2.5. Degree of competition

Chapter 7. Competitive Landscape

7.1.1. Company Market Share/Positioning Analysis

7.1.2. Key Strategies Adopted by Players

7.1.3. Vendor Landscape

7.1.3.1. List of Suppliers

7.1.3.2. List of Buyers

Chapter 8. Global Small Interfering RNA (siRNA) Therapeutics Market, By Application

8.1. Small Interfering RNA (siRNA) Therapeutics Market Revenue and Volume Forecast, by Application

8.1.1. Cancer

8.1.1.1. Market Revenue and Volume Forecast

8.1.2. Neurological Disorders    

8.1.2.1. Market Revenue and Volume Forecast

8.1.3. Cardiovascular Diseases

8.1.3.1. Market Revenue and Volume Forecast

8.1.1. Ophthalmic Diseases

8.1.1.1. Market Revenue and Volume Forecast

8.1.1. Infectious Diseases

8.1.1.1. Market Revenue and Volume Forecast

8.1.1. Other Therapeutic Applications

8.1.1.1. Market Revenue and Volume Forecast

Chapter 9. Global Small Interfering RNA (siRNA) Therapeutics Market, By Delivery System

9.1. Small Interfering RNA (siRNA) Therapeutics Market Revenue and Volume Forecast, by Delivery System

9.1.1. Liposomes

9.1.1.1. Market Revenue and Volume Forecast

9.1.2. Polymers

9.1.2.1. Market Revenue and Volume Forecast

9.1.3. Lipid Nanoparticles

9.1.3.1. Market Revenue and Volume Forecast

9.1.4. Viral Vectors

9.1.4.1. Market Revenue and Volume Forecast

9.1.5. Other Delivery Systems

9.1.5.1. Market Revenue and Volume Forecast

Chapter 10. Global Small Interfering RNA (siRNA) Therapeutics Market, By Synthetic Route

10.1. Small Interfering RNA (siRNA) Therapeutics Market Revenue and Volume Forecast, by Synthetic Route

10.1.1. Chemical Synthesis

10.1.1.1. Market Revenue and Volume Forecast

10.1.2. Biotechnology

10.1.2.1. Market Revenue and Volume Forecast

10.1.3. Other Synthetic Routes

10.1.3.1. Market Revenue and Volume Forecast

Chapter 11. Global Small Interfering RNA (siRNA) Therapeutics Market, By Mechanism of Action

11.1. Small Interfering RNA (siRNA) Therapeutics Market Revenue and Volume Forecast, by Mechanism of Action

11.1.1. Gene Editing

11.1.1.1. Market Revenue and Volume Forecast

11.1.2. Gene Silencing

11.1.2.1. Market Revenue and Volume Forecast

11.1.3. MicroRNA Mimics

11.1.3.1. Market Revenue and Volume Forecast

11.1.4. Others

11.1.4.1. Market Revenue and Volume Forecast

11.1.5. siRNA-mediated mRNA decay)

11.1.5.1. Market Revenue and Volume Forecast

Chapter 12. Global Small Interfering RNA (siRNA) Therapeutics Market, Regional Estimates and Trend Forecast

12.1. North America

12.1.1. Market Revenue and Volume Forecast, by Application

12.1.2. Market Revenue and Volume Forecast, by Delivery System

12.1.3. Market Revenue and Volume Forecast, by Synthetic Route

12.1.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.1.5. U.S.

12.1.5.1. Market Revenue and Volume Forecast, by Application

12.1.5.2. Market Revenue and Volume Forecast, by Delivery System

12.1.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.1.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.1.6. Rest of North America

12.1.6.1. Market Revenue and Volume Forecast, by Application

12.1.6.2. Market Revenue and Volume Forecast, by Delivery System

12.1.6.3. Market Revenue and Volume Forecast, by Synthetic Route

12.1.6.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.2. Europe

12.2.1. Market Revenue and Volume Forecast, by Application

12.2.2. Market Revenue and Volume Forecast, by Delivery System

12.2.3. Market Revenue and Volume Forecast, by Synthetic Route

12.2.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.2.5. UK

12.2.5.1. Market Revenue and Volume Forecast, by Application

12.2.5.2. Market Revenue and Volume Forecast, by Delivery System

12.2.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.2.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.2.6. Germany

12.2.6.1. Market Revenue and Volume Forecast, by Application

12.2.6.2. Market Revenue and Volume Forecast, by Delivery System

12.2.6.3. Market Revenue and Volume Forecast, by Synthetic Route

12.2.6.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.2.7. France

12.2.7.1. Market Revenue and Volume Forecast, by Application

12.2.7.2. Market Revenue and Volume Forecast, by Delivery System

12.2.7.3. Market Revenue and Volume Forecast, by Synthetic Route

12.2.7.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.2.8. Rest of Europe

12.2.8.1. Market Revenue and Volume Forecast, by Application

12.2.8.2. Market Revenue and Volume Forecast, by Delivery System

12.2.8.3. Market Revenue and Volume Forecast, by Synthetic Route

12.2.8.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.3. APAC

12.3.1. Market Revenue and Volume Forecast, by Application

12.3.2. Market Revenue and Volume Forecast, by Delivery System

12.3.3. Market Revenue and Volume Forecast, by Synthetic Route

12.3.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.3.5. India

12.3.5.1. Market Revenue and Volume Forecast, by Application

12.3.5.2. Market Revenue and Volume Forecast, by Delivery System

12.3.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.3.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.3.6. China

12.3.6.1. Market Revenue and Volume Forecast, by Application

12.3.6.2. Market Revenue and Volume Forecast, by Delivery System

12.3.6.3. Market Revenue and Volume Forecast, by Synthetic Route

12.3.6.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.3.7. Japan

12.3.7.1. Market Revenue and Volume Forecast, by Application

12.3.7.2. Market Revenue and Volume Forecast, by Delivery System

12.3.7.3. Market Revenue and Volume Forecast, by Synthetic Route

12.3.7.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.3.8. Rest of APAC

12.3.8.1. Market Revenue and Volume Forecast, by Application

12.3.8.2. Market Revenue and Volume Forecast, by Delivery System

12.3.8.3. Market Revenue and Volume Forecast, by Synthetic Route

12.3.8.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.4. MEA

12.4.1. Market Revenue and Volume Forecast, by Application

12.4.2. Market Revenue and Volume Forecast, by Delivery System

12.4.3. Market Revenue and Volume Forecast, by Synthetic Route

12.4.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.4.5. GCC

12.4.5.1. Market Revenue and Volume Forecast, by Application

12.4.5.2. Market Revenue and Volume Forecast, by Delivery System

12.4.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.4.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.4.6. North Africa

12.4.6.1. Market Revenue and Volume Forecast, by Application

12.4.6.2. Market Revenue and Volume Forecast, by Delivery System

12.4.6.3. Market Revenue and Volume Forecast, by Synthetic Route

12.4.6.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.4.7. South Africa

12.4.7.1. Market Revenue and Volume Forecast, by Application

12.4.7.2. Market Revenue and Volume Forecast, by Delivery System

12.4.7.3. Market Revenue and Volume Forecast, by Synthetic Route

12.4.7.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.4.8. Rest of MEA

12.4.8.1. Market Revenue and Volume Forecast, by Application

12.4.8.2. Market Revenue and Volume Forecast, by Delivery System

12.4.8.3. Market Revenue and Volume Forecast, by Synthetic Route

12.4.8.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.5. Latin America

12.5.1. Market Revenue and Volume Forecast, by Application

12.5.2. Market Revenue and Volume Forecast, by Delivery System

12.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.5.5. Brazil

12.5.5.1. Market Revenue and Volume Forecast, by Application

12.5.5.2. Market Revenue and Volume Forecast, by Delivery System

12.5.5.3. Market Revenue and Volume Forecast, by Synthetic Route

12.5.5.4. Market Revenue and Volume Forecast, by Mechanism of Action

12.5.6. Rest of LATAM

12.5.6.1. Market Revenue and Volume Forecast, by Application

12.5.6.2. Market Revenue and Volume Forecast, by Delivery System

12.5.6.3. Market Revenue and Volume Forecast, by Synthetic Route

12.5.6.4. Market Revenue and Volume Forecast, by Mechanism of Action

Chapter 13. Company Profiles

13.1. Silence Therapeutics

13.1.1. Company Overview

13.1.2. Product Offerings

13.1.3. Financial Performance

13.1.4. Recent Initiatives

13.2. Silenseed Ltd

13.2.1. Company Overview

13.2.2. Product Offerings

13.2.3. Financial Performance

13.2.4. Recent Initiatives

13.3. Sylentis, S.A.

13.3.1. Company Overview

13.3.2. Product Offerings

13.3.3. Financial Performance

13.3.4. Recent Initiatives

13.4. Quark Pharmaceuticals

13.4.1. Company Overview

13.4.2. Product Offerings

13.4.3. Financial Performance

13.4.4. Recent Initiatives

13.5. Sanofi Genzyme

13.5.1. Company Overview

13.5.2. Product Offerings

13.5.3. Financial Performance

13.5.4. Recent Initiatives

13.6. Dicerna Pharmaceuticals

13.6.1. Company Overview

13.6.2. Product Offerings

13.6.3. Financial Performance

13.6.4. Recent Initiatives

13.7. Novo Nordisk

13.7.1. Company Overview

13.7.2. Product Offerings

13.7.3. Financial Performance

13.7.4. Recent Initiatives

13.8. Novartis

13.8.1. Company Overview

13.8.2. Product Offerings

13.8.3. Financial Performance

13.8.4. Recent Initiatives

13.9. GSK

13.9.1. Company Overview

13.9.2. Product Offerings

13.9.3. Financial Performance

13.9.4. Recent Initiatives

13.10. Aro Biotherapeutics 

13.10.1. Company Overview

13.10.2. Product Offerings

13.10.3. Financial Performance

13.10.4. Recent Initiatives

Chapter 14. Research Methodology

14.1. Primary Research

14.2. Secondary Research

14.3. Assumptions

Chapter 15. Appendix

15.1. About Us

15.2. Glossary of Terms

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Frequently Asked Questions

Answer : The small interfering RNA (siRNA) therapeutics market size is expected to increase from USD 193.95 billion in 2025 to USD 528.78 billion by 2035.

Answer : The small interfering RNA (siRNA) therapeutics market is expected to grow at a compound annual growth rate (CAGR) of around 10.55% from 2026 to 2035.

Answer : The major players in the small interfering RNA (siRNA) therapeutics market include Alnylam, Silence Therapeutics, Silenseed Ltd, Sylentis, S.A., Sanofi Genzyme, Quark Pharmaceuticals, Dicerna Pharmaceuticals, Arrowhead Pharmaceuticals, Novartis, Novo Nordisk, Johnson & Johnson company, GSK, Aro Biotherapeutics, and Other Market Players.

Answer : The driving factors of the small interfering RNA (siRNA) therapeutics market are growing due to rising genetic and chronic diseases, advances in RNA delivery technology, and increasing demand for precision medicines. 

Answer : North America region will lead the global small interfering RNA (siRNA) therapeutics market during the forecast period 2026 to 2035.

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