Cell Cryopreservation Market (By Type: Cell Freezing Media, Equipment, Consumables, Others; By Application: Stem Cells, Oocytes Cells, Sperm Cells, Others; By End User: Pharmaceutical and Biotechnology Company, Research Institute, Biobanks, IVF Clinics, Others) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2023-2032


The global cell cryopreservation market size reached USD 13.22 billion in 2023 and is expected to hit around USD 60.89 billion by 2032, poised to grow at a CAGR of 18.50% during the forecast period from 2023 to 2032.

Cell Cryopreservation Market Size 2023 To 2032

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Key Takeaways

  • North America contributed more than 46% of revenue share in 2022.
  • Asia Pacific is estimated to expand the fastest CAGR between 2023 and 2032.
  • By type, the consumables segment has held the largest market share of 44% in 2022.
  • By type, the cell freezing media segment is anticipated to grow at a remarkable CAGR of 23.5% between 2023 and 2032.
  • By application, the stem cells segment generated over 36% of revenue share in 2022.
  • By application, the sperm cells segment is expected to expand at the fastest CAGR over the projected period.
  • By end-user, the IVF clinics segment had the largest market share of 42% in 2022.
  • By end-user, the biobanks segment is expected to expand at the fastest CAGR over the projected period.

Cell Cryopreservation Market in the U.S. 2023 To 2032

The U.S. cell cryopreservation market size was valued at USD 4.26 billion in 2023 and is expected to reach USD 19.61 billion by 2032, growing at a CAGR of 18.50% from 2023 to 2032.

U.S. Cell Cryopreservation Market Size 2023 To 2032

North America has held the largest revenue share of 46% in 2022. In North America, the cell cryopreservation market is marked by a strong emphasis on technological innovation and extensive research in cryopreservation methods. The region witnesses a surge in demand for advanced freezing techniques and cryoprotectants, driven by a robust biomedical research sector and the increasing adoption of personalized medicine. Strategic collaborations between industry players and research institutions contribute to the rapid evolution of cryopreservation technologies in North America.

Cell Cryopreservation Market Share, By Region, 2022 (%)

Asia Pacific is estimated to observe the fastest expansion. Asia-Pacific exhibits dynamic trends in the cell cryopreservation market, with a notable focus on expanding biobanking activities and the growing influence of regenerative medicine. The region experiences a rise in demand for cryopreservation solutions in emerging economies, driven by a flourishing healthcare sector and increasing awareness of stem cell applications. Asia Pacific showcases a trend towards the adoption of automated cryopreservation systems, reflecting a forward-looking approach to technological integration in the field of cell preservation.

In Europe, the cell cryopreservation market reflects a progressive landscape with a strong emphasis on sustainable practices. The region sees a surge in research collaborations and investments, fostering advancements in cryopreservation technologies. Growing adoption of serum-free cryopreservation methods and adherence to stringent regulatory standards define Europe's approach. The market is characterized by a commitment to ethical and high-quality cell preservation practices, aligning with the region's focus on advancing biomedical sciences.

Advancements in cryoprotectants and freezing techniques significantly boost the cell cryopreservation market by enhancing cell viability during freezing processes. Improved formulations mitigate cellular damage, broaden the scope of applications, and foster the development of more effective cryopreservation solutions. This, in turn, stimulates market growth, meeting the increasing demands of diverse biomedical disciplines.

Cell Cryopreservation Market Overview

The cell cryopreservation market involves the preservation of cells at extremely low temperatures, typically below -130°C, to maintain their viability for various applications, such as regenerative medicine, drug discovery, and biobanking. This process prevents cellular damage and allows for long-term storage.

Key players in the market provide cryopreservation solutions, including specialized freezing equipment, cryoprotectants, and services. The market's growth is driven by increasing applications in stem cell research, organ transplantation, and vaccine development, with a focus on preserving cells' functional integrity and enabling their use in diverse biomedical fields.

Growth Factors

  • Increasing applications in stem cell research, organ transplantation, and vaccine development drive the demand for cell cryopreservation solutions.
  • The rising importance of biobanks for storing cells for research and clinical purposes contributes to market growth.
  • The expanding field of cellular therapies, including CAR-T cell therapies, propels the need for effective cell cryopreservation methods.
  • The emphasis on precision medicine and personalized treatments creates opportunities for cell cryopreservation in preserving patient-specific cells.
  • Ongoing developments in freezing equipment and cryoprotectants enhance the efficiency of cell cryopreservation methods.
  • Rising Demand for Personalized Medicine: The focus on personalized medicine fuels the need for long-term cell storage and cryopreservation solutions.
  • The industry witnesses a trend towards incorporating automation and robotics in cryopreservation processes for increased efficiency.
  • The move towards serum-free cryopreservation methods addresses concerns related to cellular damage and introduces more sustainable practices.
  • Opportunities exist for companies developing novel cryopreservation technologies and solutions.
  • Providing specialized cryopreservation services for biobanking facilities presents a niche business opportunity.
  • Companies can explore opportunities by expanding their cryopreservation services globally to meet the increasing international demand.
  • Collaborating with research institutions for joint ventures and technology transfer initiatives opens avenues for market growth.

Cell Cryopreservation Market Scope

Report Coverage Details
Growth Rate from 2023 to 2032 CAGR of 18.50%
Market Size in 2023 USD 13.22 Billion
Market Size by 2032 USD 60.89 Billion
Largest Market North America
Base Year 2022
Forecast Period 2023 to 2032
Segments Covered By Type, By Application, and By End User
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa


Cell Cryopreservation Market Dynamics

Driver

Growing biobanking activities and advancements in cellular therapies

Growing biobanking activities and advancements in cellular therapies are significant drivers surging the demand for the cell cryopreservation market. The expanding biobanking landscape, where biological samples are stored for research and clinical purposes, necessitates effective cell cryopreservation methods to maintain the viability and functionality of diverse cell types over extended periods. Biobanks serve as repositories for valuable cellular materials, including stem cells and tissues, driving the need for robust cryopreservation solutions to ensure the long-term integrity of stored specimens.

Advancements in cellular therapies, particularly in CAR-T cell therapies, further amplify the demand for cell cryopreservation. Cellular therapies involve the manipulation and infusion of patient-specific or donor-derived cells, requiring precise preservation methods to maintain their therapeutic efficacy. As cellular therapies expand, the reliance on cryopreservation for preserving these specialized cells grows, reflecting a symbiotic relationship between the cell cryopreservation market and the evolving landscape of biobanking and cellular-based therapeutic innovations.

Restraint

Cell damage concerns and technical complexity

Cell damage concerns pose a significant restraint for the cell cryopreservation market. The process of freezing and thawing cells inherently carries the risk of cellular damage, impacting their structural integrity and functionality. Cryoprotectants, while essential for preventing ice crystal formation, can introduce additional stress on cells. Ensuring minimal damage during cryopreservation is a complex challenge, particularly for delicate cell types crucial in biomedical applications. Addressing these concerns is pivotal for maintaining the viability and efficacy of preserved cells, as damaged cells may compromise the success of applications in regenerative medicine, drug development, and biobanking.

Technical complexity represents a formidable obstacle in the widespread adoption of cell cryopreservation methods. The intricacies involved in precisely controlling freezing and thawing rates, selecting optimal cryoprotectants, and customizing protocols for diverse cell types make the process technically challenging. Standardizing cryopreservation procedures across different cell lines and applications is intricate due to the diverse requirements of various cells. This complexity not only hinders uniform practices but also necessitates specialized expertise, limiting the accessibility and ease of implementation for researchers and organizations seeking to leverage cryopreservation technologies.

Opportunity

Advancements in cryoprotectants and freezing techniques

Advancements in cryoprotectants and freezing techniques are key drivers propelling the demand for the cell cryopreservation market. Continuous research and development efforts in cryoprotectant formulations and freezing methodologies are revolutionizing the field, ensuring enhanced cell viability and functionality post-thaw. Innovative cryoprotectants with improved properties, such as reduced cytotoxicity and increased permeability, contribute to minimizing cellular damage during the freezing and thawing process.

These advancements cater to the evolving needs of diverse applications, including regenerative medicine, stem cell research, and cellular therapies. The ability to preserve cells with greater efficiency and minimal damage not only expands the scope of cryopreservation across various biomedical disciplines but also aligns with the growing demand for precision medicine. As cellular-based therapies gain prominence, the market experiences a surge in demand for advanced cryopreservation techniques, reflecting the pivotal role these innovations play in ensuring the therapeutic efficacy of preserved cells in groundbreaking medical interventions.

Type Insights

According to type, the consumables segment held 44% revenue share in 2022. Consumables in the cell cryopreservation market refer to the materials used in the cryopreservation process, including cryovials, cryobags, and labels. These consumables are designed to ensure the safe and efficient storage of cells during freezing and thawing. Trends in consumables involve the adoption of specialized containers with improved insulation properties and the development of eco-friendly, single-use options to address sustainability concerns in the cryopreservation workflow.

The cell freezing media segment is anticipated to expand at a significant CAGR of 23.5% during the projected period. Cell freezing media in the cell cryopreservation market are formulations designed to protect cells during the freezing process. These media typically contain cryoprotectants and other additives to minimize ice crystal formation and cellular damage.

Trends in cell freezing media include the use of serum-free formulations, allowing for more defined and controlled cryopreservation conditions. Additionally, there is a focus on optimizing media compositions to enhance post-thaw cell viability and functionality, catering to the evolving needs of various applications in biobanking and biomedical research.

Application Insights

Based on the application, the stem cells segment held the largest market share of 36% in 2022. In the cell cryopreservation market, the preservation of stem cells is a critical application. Cryopreservation of stem cells, renowned for their regenerative capabilities, is integral to applications in regenerative medicine and therapeutic interventions.

A notable trend encompasses the formulation of specialized cryopreservation protocols tailored to distinct types of stem cells. These protocols are designed to uphold the viability and functionality of stem cells throughout the freezing and thawing processes. This trend significantly contributes to the progression of regenerative therapies, ensuring that preserved stem cells retain their regenerative potential, thereby fostering advancements in the field of regenerative medicine.

On the other hand, the sperm cells segment is projected to grow at the fastest rate over the projected period. Cell cryopreservation plays a vital role in preserving sperm cells, primarily utilized in reproductive medicine. The market trend focuses on optimizing cryopreservation techniques for sperm cells, addressing factors such as motility and DNA integrity. This aligns with the increasing demand for assisted reproductive technologies, offering solutions for fertility preservation and aiding in various reproductive interventions.

End-user Insights

In 2022, the IVF clinics segment had the highest market share of 42% based on the end user. In the cell cryopreservation market, IVF clinics are significant end-users, utilizing cryopreservation to store embryos, eggs, and sperm for assisted reproductive technologies. A notable trend involves the increasing adoption of vitrification, a rapid freezing technique, for improved cell survival rates during thawing. This trend aligns with the rising demand for fertility preservation and the broader acceptance of in vitro fertilization methods.

The biobanks segment is anticipated to expand at the fastest rate over the projected period. Biobanks play a crucial role by storing diverse cell types for research and therapeutic purposes. A trend in biobanking involves incorporating automated cryopreservation systems for streamlined and standardized cell storage, enhancing the efficiency of large-scale storage initiatives. This trend addresses the challenges related to manual processes and supports the growing demand for well-preserved cell samples in various research domains.

Recent Developments

  • In 2023, BioLife Solutions, Inc. and the broader biopharma markets have introduced the IntelliRate i67C, a novel large-capacity controlled-rate freezer (CRF). This tabletop freezer addresses a significant client demand for enhanced volume production of cell treatments, expanding the CRF product range to cater to various shape factors in the biopharmaceutical industry.
  • In 2022, AMSBIO has unveiled 'STEM-CELLBANKER EX,' an advanced cryopreservation product aimed at expediting cell therapy product development. This chemically defined cryopreservation media solution contains inactive ingredients approved for intravenous administration, offering a high-quality solution for preserving stem cells and contributing to the advancement of cell therapy research and development.

Cell Cryopreservation Market Players

  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • GE Healthcare
  • Lonza Group Ltd.
  • STEMCELL Technologies Inc.
  • BioLife Solutions, Inc.
  • Cryolife, Inc.
  • Organ Recovery Systems Inc.
  • Custom Biogenic Systems
  • Sartorius AG
  • Takara Bio Inc.
  • Chart Industries, Inc.
  • Biocision, LLC
  • Cardinal Health, Inc.
  • Helmer Scientific

Segments Covered in the Report

By Type

  • Cell Freezing Media
  • Equipment
  • Consumables
  • Others

By Application

  • Stem Cells
  • Oocytes Cells
  • Sperm Cells
  • Others

By End User

  • Pharmaceutical and Biotechnology Company
  • Research Institute
  • Biobanks
  • IVF Clinics
  • Others

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Frequently Asked Questions

How big is the cell cryopreservation industry?
The global cell cryopreservation market size is expected to increase USD 60.89 billion by 2032 from USD 13.22 billion in 2023.
What is the growth rate of the cell cryopreservation industry?
The global cell cryopreservation market will register growth rate of 18.50% between 2023 and 2032.
Who are the prominent players operating in the cell cryopreservation market?
The major players operating in the cell cryopreservation market are Thermo Fisher Scientific Inc., Merck KGaA, GE Healthcare, Lonza Group Ltd., STEMCELL Technologies Inc., BioLife Solutions, Inc., Cryolife, Inc., Organ Recovery Systems Inc., Custom Biogenic Systems, Sartorius AG, Takara Bio Inc., Chart Industries, Inc., Biocision, LLC, Cardinal Health, Inc., Helmer Scientific, and Others.
Which are the driving factors of the cell cryopreservation market?
The driving factors of the cell cryopreservation market are the growing biobanking activities and advancements in cellular therapies.
Which region will lead the global cell cryopreservation market?
North America region will lead the global cell cryopreservation market during the forecast period 2023 to 2032.

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