The North America parenteral nutrition market size surpassed USD 3.13 billion in 2025 and is predicted to reach around USD 5.45 billion by 2035, registering a CAGR of 5.7% from 2026 to 2035. The rising prevalence of chronic conditions and gastrointestinal disorders, and the rapid expansion of home parenteral nutrition, are driving the North American industry for parenteral nutrition.

North America Parenteral Nutrition Market Statical Scope

The National Home Infusion Association (NHIA) published a white paper addressing the economic challenges faced by home parenteral nutrition services. This report ensures sustainable access to home parenteral nutrition and includes trends, cost, and reimbursement patterns.

In August 2025, the National Home Infusion Association (NHIA) reported that home parenteral nutrition serves approximately 32,000 Americans annually who face difficulties in absorbing nutrients through their gastrointestinal tract due to medical conditions. It has also been proclaimed that home parenteral nutrition has reduced healthcare costs by 32-36% over hospital-based care.

North America Parenteral Nutrition Market Share, By Nutrient Type, 2025 (%)

• Single Dose Amino Acid Solution -32%- The single dose amino acid solution segment dominated the market in 2025, with a share of 35%, owing to its importance for protein synthesis and supporting overall nutritional needs. It is also highly adopted due to the shift towards precise and patient-specific care, and a surge in chronic and critical illnesses. It results in the rapid expansion of home healthcare due to the ease of administration, enhanced formulation stability, and reduced risk of contamination.
• Parenteral Lipid Emulsion - The parenteral lipid emulsion segment held a 20% share and is expected to grow in the coming years, driven by a supply of essential fatty acids for energy and cellular function. It is in high demand due to the shift towards advanced and balanced multi-oil formulations. They deliver reduced liver toxicity and immunomodulatory effects.

North America Parenteral Nutrition Market Share, By Stage Type, 2025 (%)

• Adult - The adult segment dominated the market in 2025 with a share of 70%, supported by the administration of most parenteral nutrition to adults with various health conditions. The longer life expectancies, hospital readmissions, and severe protein-energy malnutrition lead to the increased demand for parenteral nutrition among adults. It is also supported by the use of clinical nutrition solutions by long-term care clinics to combat conditions of adults.
• Pediatrics - The pediatrics segment held a 30% share and is expected to grow in the coming years, driven by efforts to address the specialized nutritional needs of children requiring clinical nutrition support. The rising incidence of preterm births and low birth weights of babies leads to the increased need for parenteral nutrition. Preterm infants who have underdeveloped gastrointestinal tracts require immediate intravenous nutrition to support early-life growth.

North America Parenteral Nutrition Market Share, By Indication, 2025 (%)

• Cancer Care - The cancer care segment dominated the market in 2025, with a share of 25%, owing to the growing need for parenteral nutrition for cancer patients during treatment, such as chemotherapy. The global cancer cases and complications from advanced tumors drive the need for parenteral nutrition in cancer care. These complications include severe dysphagia, bowel obstructions, radiation enteritis, and cachexia.
• Malabsorption/GI Disorder/Diarrhea - The malabsorption/GI disorder/diarrhea segment held a 20% share and is expected to grow in the coming years, driven by nutritional support for patients unable to absorb nutrients properly through the gastrointestinal tract. The technological, clinical, and demographic shifts have driven segmental growth. It is also led by the rising incidence of chronic intestinal failure, severe refractory diarrhea, and oncology-related malabsorption.

North America Parenteral Nutrition Market Share, By Sales Channel, 2025 (%)

• Institutional - The institutional segment dominated the market in 2025, with a share of 75%, accelerated by large-scale purchases and distribution in hospitals and healthcare institutions for clinical use. The rising hospital admissions, a surge in premature births, and bulk purchasing economies are driving this sales channel. There is a heavy dependency of acute and critical care settings on inpatient parenteral nutrition therapy.
• Retail - The retail segment held a 15% share and is expected to grow in the coming years, driven by consumers gaining access to parenteral nutrition products via pharmacies and healthcare stores. Retail sales are also driven by the rising preference for outpatient care models and the shift to home healthcare. Retail pharmacies provide easier access to specialized bags and intravenous formulas without the need for hospital visits

Competitive Landscape

The major industrial players in the parenteral nutrition market in North America are Fresenius Kabi, Baxter International, B. Braun AG, ICU Medical, and Option Care Health.

They presented their broad product offerings, such as multi-chamber bags, fish oil emulsion, delivery systems, customized solutions, and nutrition for pediatrics and neonatal care. Option Care Health is dedicated to providing home infusion and parenteral nutrition services. The major driving forces for the market are efficiency in hospitals, home care expansion, and personalized nutrition.

Segments Covered in the Report

By Nutrient Type

• Single Dose Amino Acid Solution
• Parenteral Lipid Emulsion
• Carbohydrates
• Trace Elements
• Vitamins and Minerals

By Stage Type

• Adult
• Pediatrics

By Indication

• Cancer Care
• Malabsorption/GI Disorder/Diarrhea
• Alzheimer's
• Nutrition Deficiency
• Diabetes
• Chronic Kidney Diseases
• Orphan Diseases
• Dysphagia
• Pain Management
• Others

By Sales Channel

• Institutional
• Retail
• Online