Cell Lysis & Disruption Market Size To Rise USD 11.11 Bn By 2032

Published Date : 17 Jan 2024

The global cell lysis & disruption market size exceeded USD 4.8 billion in 2022 and is expected to rise to USD 11.11 billion by 2032, poised to grow at a CAGR of 8.80% from 2023 to 2032.

Cell Lysis & Disruption Market Size and Growth Rate From 2023 To 2032

Market Overview

Cell lysis is a process in which cell membranes are broken down to obtain cellular contents, including nucleic acids, proteins, and organelles. It is considered one of the most critical steps in biological and biotechnological applications. The market for cell lysis and disruption consists of various goods that break apart cells and remove their contents, including detergents, homogenizers, and mechanical disruptors. As these trends continue and new applications develop, the cell lysis and disruption market is anticipated to expand during the ensuing years.

Advancements in releasing organelles have made cell lysis techniques more popular. As the demand for purifying biopharmaceutical products increases, the downstream market is expected to grow. This field also has ongoing improvements in proteomics, metabolomics, and personalized medicine. The market is likely to be driven by increased investments in biotechnology from governments, private organizations, and research markets. The rising incidence of diseases and the demand for new treatments will also contribute to market growth.

The market is also driven by increasing demand for biopharmaceuticals and personalized medicine, requiring efficient and reliable protein purification and cell lysis techniques. Improvements in cell-based research, the creation of new technologies, and increasing investments in biotechnology research and development are also factors supporting market expansion.

Moreover, demand for cell breakdown and breakdown products is expected to grow as R&D spending in the life sciences sector grows and researchers work to develop new drugs and therapies. Advances in technology and automation can increase the efficiency and accuracy of cell lysis and lysis processes, thus accelerating market expansion.

  • The Department of Biotechnology (DBT) in India initiated a project to sequence 1,000 SARS-CoV-2 genomes collected from various parts of the country. The heightened research activities utilizing various processes led to an increased demand for cell lysis devices and reagents.
  • According to GLOBOCAN, there were approximately 19,292,789 new cancer cases and approximately 9,958,133 cancer deaths worldwide. As the prevalence of infectious diseases and cancers increases, the use of cell samples in drug research and development is also growing, which is expected to support the growth of the cell lysis market.

Regional Snapshot

North America is the most critical global cell lysis and disruption market and accounts for a significant share. Regional market development, various regulatory entities and frameworks, regional trade, and the presence of leading companies in the region are discussed in detail in the report. An in-depth look at the region's businesses, competition, and recent innovations has found several factors helping the industry and economic growth. 

Growing demand for cell-based cancer therapies is also expected to fuel the growth of the cell lysis market. The increasing prevalence and incidence of several diseases and increasing R&D expenditures in North America drive the need for an enhanced R&D scenario in all areas of the life sciences.

  • In January 2023, Par Pacific Holdings, Inc. recently shared that Hawaiian Electric has chosen their 30-megawatt renewable cogeneration development project as one of the top contenders. This selection is part of the process following a proposal request, specifically for secure and renewable electricity generation.
  • In December 2023, PerkinElmer, a primary global provider of analytical services, acquired Covaris, a company known for developing solutions in life sciences. This merger is expected to boost Covaris's growth and allow PerkinElmer to extend its life sciences offerings into the rapidly growing diagnostics market.

Cell Lysis & Disruption Market Report Scope

Report Coverage Details
Market Revenue in 2023 USD 5.20 Billion
Projected Forecast Revenue by 2032 USD 11.11 Billion
Growth Rate from 2023 to 2032 CAGR of 8.8%
Largest Market North America
Base Year 2022
Forecast Period 2023 to 2032
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

Market Dynamics 


Rise of chronic illnesses

With the rise of chronic and infectious diseases, there is a high demand for research laboratories and institutions, as well as biopharmaceutical and biotechnology companies, increasing the overall demand for medicines. According to the 2022 report of the American Cancer Society, approximately 1,918,030 new cancers were expected in the United States in 2022. This high number of cancer cases indicates the need for research and diagnosis of the disease. This is likely to contribute to the growth of the segment.

Wide variety of available tools

Instruments are tools used to break cells, and there are different types, such as sonicators, homogenizers, French presses, microfluidizers, and more. Homogenizers and sonicators are often used to break cells apart, with sonicators being especially popular. Technological advancements have made microfluidic devices more familiar in cell lysis.

  • In April 2022, a study published in the Biotechnology Journal mentioned that microfluidic technology is widely used for cell lysis. This is particularly important in diagnosing various diseases, as it helps isolate and break down red blood cells.

Monetary investments and grants

Growing investment in research and development of biotechnological processes by scientists of various organizations, including the government and private sector, is expected to propel the market significantly. Several institutions, including state and commercial enterprises, provide substantial funding for research and development of biotechnology processes and academia. In addition, increasing demand for innovative treatments and the prevalence of chronic diseases is supporting the market expansion.


Stringent regulatory compliances

The increased use of methods to break cells in the later stages of making bio-therapeutics and other genetically engineered products enhances overall market growth. Additionally, substantial investments from both government and private sectors in research and development for biotechnological processes are anticipated to push the market forward significantly. However, challenges related to meeting regulations and mechanical issues in applying processes at a tiny scale could slow market growth.


Preference for personalized medications

The market is projected to grow due to increasing emphasis on personalized healthcare, which often involves cell lysis and disruptive therapies to collect and study patient-specific biological components. Personalized medicine is one of the latest developments in genetic research, which provides customized treatment according to the patient's specific needs and is very important in the prevention, diagnosis, prognosis, and treatment of diseases. 

Development in the genomic research industry

As genomic research grows in medical diagnostics, biotechnology, and pharmaceuticals, it becomes crucial to extract DNA and RNA accurately. Cell lysis techniques using enzymes, chemicals, and mechanical methods are critical for isolating genetic material. This ensures high-quality material for various applications. The market is responding to the increasing need for reliable and efficient methods to extract genetic material, highlighting the critical role of cell lysis in advancing genetic research and diagnostic capabilities. This advancement can create further market opportunities for the market.

Rapidly expand multidisciplinary applications

Cell lysis and disruption are crucial for diagnosing pathogens and conducting lab immunoassays. They play a vital role in drug screening, studying protein structure and function, diagnosing cancer, understanding messenger ribonucleic acid transcriptome, and examining the composition of lipids, nucleic acids, and proteins. The expanding use of biotechnology in agriculture, pharmaceuticals, and bio-service industries mainly boosts the global cell lysis and disruption market. Additionally, increased government support for adopting biotechnology-based screening options and treatments drives cell lysis and disruption market growth.

Recent Developments

  • In September 2022, SCIENION and Cellenion introduced the proteoCHIP LF 48, a tool for preparing samples in label-free single-cell proteomics on the cellphone platform.
  • In March 2022, Sanofi and IGM Biosciences, Inc. agreed to collaborate exclusively worldwide to develop and commercialize IgM antibody agonists targeting three oncology and three immunology/inflammation targets.

Key Market Players

  • Thermo Fisher Scientific, Inc.
  • Danaher Corporation
  • Qiagen NV
  • Parr Instrument Company
  • Covaris Inc.
  • Merck KGaA
  • Bio-Rad Laboratories
  • F. Hoffmann-La Roche Ltd.
  • Claremont BioSolutions
  • Becton Dickinson & Company

Market Segmentation

By Product

  • Instruments
  • Reagents

By Cell Type

  • Bacteria Cells
  • Mammalian Cells
  • Plant Cells
  • Yeast/Fungi/Algae

By Application

  • Cell Organelle Isolation
  • Protein Isolation
  • Downstream Processing
  • Nucleic Acid Isolation

By End Use

  • Hospitals and Diagnostic Laboratories
  • Cell Banks
  • Academic and Research Institutions
  • Pharma & Biotechnology Companies

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