November 2025
The global intravascular lithotripsy market revenue reached USD 1.07 billion in 2025 and is predicted to attain around USD 3.40 billion by 2033 with a CAGR of 15.57%. This market is expanding due to the rising prevalence of calcified cardiovascular disease, combined with strong clinical evidence, favourable reimbursement updates, and major industry M&A activity, which is accelerating IVL adoption globally.

The mechanism of action of intravascular lithotripsy (IVL) involves using pulsed sonic pressure waves that specifically disrupt and break down calcium in place, thereby altering the vessel's compliance while minimizing injury and preserving the vessel wall's fibroelastic components. Clinical data showing IVL's safety and effectiveness in heavily calcified lesions, with lower complication rates and improved stent expansion, is quickly increasing clinician confidence and consideration for inclusion in guidelines. The adoption of IVL has been increasing due to the rising number of patients with coronary and peripheral indications. Advances in medical device technology open up new growth prospects.
North America dominated the intravascular lithotripsy market in 2024 due to early regulatory approvals, established reimbursement pathways, and larger hospital capital budgets. Regulatory approvals and CPT and DRG code progress from the FDA ultimately shorten the time to market entry. In the U.S., there is also a higher volume of PCI procedures performed, along with established interventional treatment teams, which facilitate the rapid adoption of devices and procedures.
Asia Pacific is poised for the fastest growth, driven by the increasing burden of cardiovascular disease, the rise in access to tertiary cardiac centers, and improved access to advanced devices that may increase procedure utilization. Although adoption is lagging behind North America's maturation of regulatory and reimbursement pathways, the engagement of clinicians with local distributors that support the education of newer devices, along with a commitment to China, Japan, and India, is expected to accelerate global uptake and device utilization.
| Report Attribute | Key Statistics |
| Market Revenue in 2025 | USD 1.07 Billion |
| Market Revenue by 2033 | USD 3.40 Billion |
| CAGR from 2025 to 2033 | 15.57% |
| Quantitative Units | Revenue in USD million/billion, Volume in units |
| Largest Market | North America |
| Base Year | 2024 |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa |
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