February 2024
10 Oct 2023
The global target sequencing and resequencing market size is anticipated to reach around USD 45.72 billion by 2032 up from USD 5.74 billion in 2022 with a CAGR of 23.06% between 2023 and 2032.
Targeted sequencing, often known as resequencing, is a technique for sequencing a sample's partial genome or specific sections of interest. It needs a pre-sequencing DNA preparation stage called Target Enrichment in which target DNA sequences are either amplified (using amplicon or multiplex PCR-based methods) or captured (using hybrid capture-based methods), and then afterwards sequenced using DNA sequencers.
Targeted resequencing and sequencing were estimated at USD 5.08 billion globally in 2022. From 2023 to 2030, the market is projected to expand at a CAGR of 22.59%. Compared to WES and whole genome sequencing, these technologies have a higher rate of market penetration and have been around for a longer period of time. Moreover, one of the factors promoting the market's expansion is the existence of a sizable number of market participants engaged in offering services for targeted sequencing.
The COVID-19 outbreak has had a beneficial effect on the market since genome sequencing has been used widely to study how COVID-19 spread and has the ability to help determine how interventions will affect future therapies. It is a quick and affordable method for detecting a variety of variations in particular genomic areas. In comparison to survey methods such as WGS, it offers an accurate analysis of the results and prevents the erroneous interpretation of data sequencing.
Moreover, a number of businesses provide targeted resequencing and sequencing services. For instance, Pacific Biosciences of California provides Sequel System, an SMRT technology that enables the targeted sequencing of variations, and Illumina of California provides targeted resequencing with the company's gene panel and array finder. Targeted sequencing panels are an economical method for giving doctors access to clear and useful information. These panels are predicted to remain the cornerstone of cancer molecular diagnostics and to be used often in the detection of solid tumours and haematological malignancies.
North America is the largest market for target sequencing and resequencing, driven by the presence of major companies in the region and the increasing adoption of NGS technologies in research and clinical applications. The US is the largest market in the region, followed by Canada.
The Asia-Pacific region is the fastest-growing market for target sequencing and resequencing, driven by the increasing adoption of NGS technologies in research and clinical applications, as well as the growing prevalence of genetic disorders in the region. China, Japan, and India are the largest markets in the region.
Europe is the second-largest market for target sequencing and resequencing, driven by the growing demand for personalized medicine and the increasing prevalence of genetic disorders. The Middle East and Africa are emerging markets for target sequencing and resequencing, driven by the growing demand for precision medicine and the increasing adoption of NGS technologies in the region. South Africa, Saudi Arabia, and the UAE are the largest markets in the region.
Target Sequencing and Resequencing Market Report Scope:
| Report Coverage | Details |
| Market Revenue in 2023 | USD 7.06 Billion |
| Projected Forecast Revenue by 2032 | USD 45.72 Billion |
| Growth Rate from 2023 to 2032 | CAGR of 23.06% |
| Largest Market | North America |
| Base Year | 2022 |
| Forecast Period | 2023 to 2032 |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa |
The market is anticipated to grow due to the ongoing technological advancements in genome sequencers and the widespread use and adoption of NGS technology. Additionally, the growing use of NGS in molecular diagnostics and precision medicine is expected to open up new market expansion prospects. Along with noninvasive prenatal testing, pharmacogenomics, and transplant medicine, NGS is anticipated to experience growing adoption in treating various diseases and infectious diseases.
The two most frequent uses of NGS sequencers in a pathology lab are targeted gene expression profiling and gene panels via qPCR. While oncology continues to be the main application of NGS in clinics, pathologists anticipate using it in other fields in the upcoming years. During the forecast period, these factors are expected to spur product demand over the forecast.
The ongoing accumulation of significant amounts of sequencing raw data, which must still be properly translated and analysed in order to advance research, diagnose, and treat diseases on a larger scale, is one of the issues the genomics community faces. A whole approach of genome sequencing can only be applied practically in particular situations, such as population genetics, basic research, or the detection of rare diseases, even with today's lower sequencing prices. Understanding disease development and guiding therapy selection in a clinical scenario or DNA samples of massively screening in industrial applications would benefit more from a focused or targeted approach.
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