Proton Therapy Market Size, Share, and Trends 2025 to 2034

The global proton therapy market size accounted for USD 648.64 million in 2025 and is predicted to surpass around USD 1995.62 million by 2034, representing a healthy CAGR of 13.30% between 2025 and 2034. The North America proton therapy market size is calculated at USD 246.18 million in 2024 and is expected to grow at a fastest CAGR of 13.42% during the forecast year.

Last Updated : 16 Jul 2025  |  Report Code : 2337  |  Category : Healthcare   |  Format : PDF / PPT / Excel

List of Contents

  • Last Updated : 16 Jul 2025
  • Report Code : 2337
  • Category : Healthcare

Proton Therapy Market Size and Forecast 2025 to 2034

The global proton therapy market size is estimated at USD 572.5 million in 2024 and is anticipated at USD 648.64 million by 2025, and expected to reach around USD 1,995.62 million by 2034, expanding at a CAGR of 13.30% from 2025 to 2034.

Proton Therapy Market Size 2025 to 2034

Proton Therapy Market Key Takeaways

  • The global proton therapy market was valued at USD 572.5 million in 2024.
  • It is projected to reach USD 1,995.62 million by 2034.
  • The proton therapy market is expected to grow at a CAGR of 13.30% from 2025 to 2034.
  • By indication, the CNS cancer segment is growing CAGR of 12.5% from 2024 to 2034.
  • By product type, the accelerator segment is poised to reach a CAGR of 13.4% from 2024 to 2034.
  • By end user, the hospital segment is expected to hit a CAGR of 13.7% from 2024 to 2034.
  • By region, Asia-Pacific is anticipated to grow at a CAGR of 15.2% from 2024 to 2034.

U.S. Proton Therapy Market Size and Growth 2025 to 2034

The U.S. proton therapy market size is evaluated at USD 172.32 million in 2024 and is predicted to be worth around USD 612.01 million by 2034, rising at a CAGR of 13.49% from 2025 to 2034.

U.S. Proton Therapy Market Size 2025 to 2034

North America holds the market with the highest market share of over 43% in 2024 with increased facilities in the region with rising chronic disorders among the population and increasing patients among the population changing lifestyle, and dietary intake. Which boosts the market of proton therapy during the forecast period. New advanced technologies developed in the market with increasing skills in the professionals and increased government support for integration of the new developments in proton therapy and to install in the health care center. The key market players are the major role players in the proton therapy market with increased funding from the key market helping to grow the market of proton therapy market.

Proton Therapy Market Share, By Region, 2024 (%)

U.S. Leads Proton Therapy with New Centers and Expanding Access

The United States leads the North America proton therapy market, which was fueled by an increasing incidence of cancer and an existing healthcare infrastructure. As of 2024, there are 43 proton therapy centers with 113 treatment rooms in the U.S. In California, much activity is happening with the approval of a next-generation UCSF cancer treatment center in the Dogpatch area of San Francisco. Proton therapy acceptance continues to grow as more insurance is covering the treatment and more patients are understanding the benefits proton therapy provides.

Japan Drives the Asia Pacific Proton Therapy Market with Technological Innovation

Asia Pacific is a region where heavy growth is occurring in the proton therapy market. Japan has led the way, having longstanding technologies and government investment. Japan is investing heavily in advanced radiotherapy technologies (such as proton therapy) in relation to its aging population and high rates of cancer. Naturally, Japan will have a growing cancer care infrastructure and professional education to prepare for an increase in proton therapy service provision.

Market Overview

Proton therapy is one of the most widely used therapy in the market with increased precision, and accuracy, of radiation therapy which involves the eradication of the cancerous cell and the prevention of the spread of malignant cells in the surrounding tissues. Proton therapy with the developments in radiation therapy is the type of particle therapy mostly used to treat the various types of cancer.

Proton therapy comes under external beam radiotherapy with deposition of the proton for radiation therapy. Increased focus on the tumor with limitations of the entry of the radiation on the tumor with reduced focus on the surrounding tissues helps to grow the market of proton therapy. Increased latest developments in proton therapy with enhanced efficiency of the proton therapy. The rising benefits of proton therapy in the prevention of various types of cancer with advanced technologies developed help to expand the market of proton therapy during the forecast period.

The outbreak of Covid-19 on proton therapy a negative and positive effects on the market. The wide spread of the coronavirus with rising infection and reduced number of patients visiting the hospital for treatment. Imposed rules in the region from the government during the covid-19 led to a decrease in the production and manufacturing of proton therapy. The post-pandemic situation in proton therapy with increased demands from the customer for radiation therapy and enhance developments in proton therapy during the forecast period.

Proton Therapy Market Growth Factors

The advance developed technologies in the proton therapy market and enhanced utilization of proton therapy in the health care sector with the increasing number of chronic disorders such as cancer with increased demands for proton therapy for patients with increased efficiency of the therapy, enhanced accuracy of the treatment with prevention of the spread of the cancerous cells to other surrounding tissues encourages to grow the market rate of proton therapy with the rising number of patients and enhance demands. Increased research and development of the proton therapy in the market for the development of the advanced technologies in the proton with increased efficiency of the proton therapy market, rising accuracy and precision help to grow the market of proton therapy.

Increased investment from the market players in the development of proton therapy and continuous research and development help to expand the market of proton therapy. Enhance availability of proton therapy with increased acquisition of the proton therapy from the customer with rising disorder help to boost the market growth. Increased providence from the government from various regions for the new development of the technologies in proton therapy and increased policies by the government such as reimbursement with increased benefits help to grow the market rate of proton therapy during the forecast period.

Impact of covid on the proton therapy market with the increased number of patients visiting the hospital helped to expand the market of proton therapy with the increasing number of patients with chronic disorders such as cancer and technologies developed with improving software development helped to expand the market of proton therapy with increased connectivity and wide acceptance of the therapy from the market to enhance the market of proton therapy.

Market Scope

Report Coverage Details
Market Size by 2034 USD 1995.62 Million
Market Size in 2025 USD 648.64 Million
Market Size in 2024 USD 572.5 Million
Growth Rate from 2024 to 2034 CAGR of 13.30%
Largest Market North America
Fastest Growing Market Asia Pacific 
Base Year 2024
Forecast Period 2025 to 2034
Segments Covered Indication, Product, Type, Set-Up Sysytems, Application Type, End User and Region
Regions Covered North America, Europe, Asia-Pacific, Latin America and Middle East & Africa

Market Dynamics

Drivers

  • Globally rising cancer disorder - Significant rise in the proton therapy market with increasing cancer disorders among the population with changing lifestyles of the people changing habits of dietary intake and increased demands from the medical sector due to the increasing number of patients and increased radiation therapies for eradication of the cancerous cell and prevention of the wide spread of the virus. Improved advanced technologies in the development of the proton therapy market with increased efficiency of the therapy with increasing results help to drive the market of proton therapy during the forecast period.
  • Increased advanced technologies in proton therapy with enhanced benefits of the proton therapy such as increased accuracy, precision, and control of the radiations involved in the proton therapy with decreasing the side effects of the proton therapy and rising demands from the market with enhanced utilization in the pediatric patients. Enhance acquisition of proton therapy in treating pediatric patients with reduced costing of the proton therapy involved for treating the pediatric patients with less adverse effects helps to boost the market of proton therapy with increased market revenue share.

Key Market Challenges

  • Visualization of the tumor - Major problem faced in proton therapy is during performing the particle therapy involved in proton therapy is low visualization of the tumor or cancerous cells involved in cancer. Enhance difficulties in visualizing only the tumor and no entry of radiation to the surrounding tissues and prevention of the disorder from spreading the malignant cells. Increased rules and effects of radiation therapy on other tissues may reduce the market growth of proton therapy.
  • The increased cost of the proton therapy - Proton therapy is involved in treating the cancer disorder and advanced developed technologies in proton therapy with increased accuracy, precision, and efficiency. This led to the increasing cost of proton therapy may hamper the market of proton therapy with reduced demands from the customers for the proton therapy. Proton therapy market with decreased revenue share and declined growth.
  • Lack of skill - Launch of new advance developed technologies in the proton therapy market with new techniques involved for carrying out the procedure in the health care center. Lack of skill among the individual for carrying out the procedure involved in proton therapy has halted the market of proton therapy with reduced market share. Decreased confidence about the treatment among patients may challenge the market of proton therapy to grow.

Key Market Opportunities

  • Rising economic development - The rapid acceptance of advanced developed technologies with increasing healthcare facilities increasing expenditure in the medical sector with rising demands from the patients due to increasing chronic disorders such as cancer help to expand the market of proton therapy during the forecast period with the increasing economy of the region and increased focus on the new developments with increased efficiency of the proton therapy in the market.
  • Government support - Governments from various regions with the active participation of the government in the health care sector with developments in radiation therapy for eradication of the cancer disorder and increasing investment from the government for integration of new therapies in the health care sector with development in the health care infrastructure help to drive the market of proton therapy during the forecast period.
  • The key market players - The key market players involved in the proton therapy play a major role to boost the market of proton therapy with an increase in research and development with constant research in proton therapy with increased efficiency, accuracy, and precision help to expand the market of proton therapy with an increase in revenue share.

Product Insights

The multi-room proton therapy systems segment held the largest share of 44.20% in the 2024 proton therapy market. The segment is accelerating due to its ability to treat various patients simultaneously, which indirectly bolsters the capacity and demand for proton therapy facilities. Previously, the multi-room proton therapy system was not much approached due to its slow treatment and rising cost. Though the development is in demand due to the need for increased throughput in cancer treatment, the ongoing efforts are focusing on cost reduction and advancing access. 

The compact proton therapy systems segment is expected to grow at a CAGR of 10.30% during the forecast period. The compact proton therapy system is opposite to multi-room but is still gaining traction with its huge value and relatability to the traditional facilities and low cost. It has advanced access to advanced cancer treatment. The development in this segment emphasizes intensity-modulated proton therapy (IMPT), a more accurate and personalized treatment catering to patient needs by improving beam control and enabling merger into compact clinical settings. 

Indication Insights

Central nervous system cancer held the highest market share of around 37% in 2024. The increasing prevalence of chronic disorders such as cancer is the largest growing disorder among the population with increasing demands from the customer for new advanced technologies in the radiation therapy market which boost the market of proton therapy. Breast cancer is also projected as the largest market rising factor with increased demands for therapies with advance technology encouraging the market of proton therapy to grow with increasing share.

End-User Insights

The hospitals segment held the largest share of 51.60% in the 2024 proton therapy market. The hospitals segment is substantially growing with the increase in demand for proton therapy. Hospitals act as an epicenter to the global development of proton therapy by initiating several developmental actions like launching new centers, fueling clinical research, partnering to advance technology and reach to access, alongside building multidisciplinary teams. The new technologies are currently working on the high-cost factor and also extending their reach to put control on long-term side effects, especially for children. Hospitals also play a major role in training specialized individuals and establishing and following safety protocols to ensure effective and knowledgeable use of this advanced cancer treatment.  

The specialty proton therapy centers segment is expected to grow at a CAGR of 9.60% during the forecast period. The specialty proton therapy centers play a pivotal role by centering and promoting the advanced techniques such s intensity-modulated proton therapy (IMPT) and pencil beam scanning, aiming at the suggestions of expertise and research to enhance the outcome and control the side effects for extreme cancer conditions. The development is strongly supported by the increasing number of centers worldwide, driven by philanthropic investments instead of personal profit. 

Component Insights

The accelerators segment held the largest share of 36.80% in the 2024 proton therapy market. The accelerators in global proton therapy involve synchrotrons, synchrocyclotrons, linear accelerators (linacs), and cyclotrons. The accelerators are a fundamental component of proton therapy systems, creating the highest energy proton beams for accurate cancer treatment. The development is targeting compact, cost-effective, and efficient solutions to reduce the facility size and extend globally. Accelerators like synchrotrons and cyclotrons speed up proton extraction from hydrogen atoms to an increased energy volume. The segment is emerging with the growing population of cancer patients. 

The imaging and monitoring systems segment is expected to grow at a CAGR of 9.40% during the forecast period. The segment includes motion management systems and technologies like CT/MRI/PET integration. The CT and MRI scans technology comes under pre-treatment planning, to address the tumour’s size and location. The segment is a major component in global proton therapy for real-time monitoring, tumour definition, and pre-treatment planning, to identify dosage delivery and beam placement to reduce the harm to the other healthy tissues. The segment is growing due to the rising prevalence of cancer and the need to address it on a quick basis. 

Technology Insights

The pencil beam scanning (PBS) segment held the largest share of 48.70% in the 2024 proton therapy market. The PBS is the most demanded technology in global proton therapy. The PBS is popularly known as a state-of-the-art technique in proton therapy, enabling greater precision and dose safety by delivering the protons in a smooth, narrow beam impromptu that is mixed to distribute the dose in multiple layers onto a tumour. The development aims to enhance delivery efficiency, merging PBS with image guidance and other advanced techniques such as FLASH therapy to expand its reach to a vast range of patients and cancer individuals. 

The intensity-modulated proton therapy (IMPT) segment is expected to grow at a CAGR of 11.10% during the forecast period. The IMPT is also called pencil beam proton therapy, which implements a magnetic mixed proton beam to accurately target the tumour to work towards the tumour-affected area, eliminating the surrounding healthy tissues damage. The IMPT plays a major role in the treatment of critical cancers, especially in the neck and head area, and the development involves advanced scanning beam technology and more, which leads the segment to the prominent growth. 

Application Insights

The pediatric cancer segment held the largest share of 27.50% in the 2024 proton therapy market. Proton therapy is essential in pediatric cancer treatment as it enables accurate doses to reduce harm to healthy organs and tissues, which diminishes the long-term side effects such as cognitive and hormonal impairments. This is required for the children whose bodies are not yet fully developed and whose organs are sensitive. The technology has been convenient with the enhancements, such as the pencil vein scanning, which adds value to the proton therapy. 

The brain tumors segment is expected to grow at a CAGR of 9.80% during the forecast period. Brain tumors are increasing in almost every age group due to various medical reasons. The proton therapy serves a conformed dose to safeguard healthy brain tissue and attack a tumor precisely, which lessens the side effects such as neurocognitive decline and enhances the quality of life, mainly for children facing this hazardous health condition. The segment is emerging with the need for appropriate therapy and treatments.  

Proton Therapy Market Companies

  • IBA Worldwide
  • Varian medical systems, Inc
  • HItachi, Ltd
  • Mevion medical systems
  • Sumitomo Heavy Industries, Ltd
  • Optivus Proton Therapy
  • Advanced Oncotherapy plc
  • ProTom International
  • Mitsubishi Corporation
  • ProNova Solutions LLC
  • Sun Nuclear Corporation
  • Provision Healthcare
  • Koninklijke Philips N.V
  • Elekta AB
  • GE Healthcare
  • Best Cyclotron Systems
  • Ray Search Laboratories
  • Permedics

Recent Developments

  • In March 2025, Apollo Hospitals partnered with Ion Beam Applications (IBA) to bring Proteus One Proton Beam Therapy to India, revolutionizing cancer care with advanced technology. The introduction of the Proteus One system, featuring the DynamicARC® beam delivery technology, is expected to revolutionize cancer treatment by providing more precise, personalized, and effective therapies.
  • In May 2024, IHH Healthcare, a world-leading integrated healthcare provider, reinforced its position as Asia’s leading cancer care provider with the official opening of the Mount Elizabeth Proton Therapy Centre in Singapore.
  • In January 2024, OncoRay launched the world’s first whole-body MRI-guided proton therapy system. This marked the start of scientific operation using the prototype, which is designed to enable real-time MRI tracking of moving tumours during proton therapy.
  • In the year 2021 April, the Collaboration of Tractebel and IBA worldwide with increased support to the agreement and increased designing of the proton therapy and improved infrastructures.
  • In the year 2019 January, Varian Medical System, inc collaborated with Oncora medical. Enhance market rate with the rising collaboration of companies for enhancing market growth. Increased software developments with enhance accuracy and precision of the newly developed proton therapy in prevention of the oncology disorder.

Segments Covered in the Report

By Product Type

  • Single-Room Proton Therapy Systems
  • Multi-Room Proton Therapy Systems
  • Compact Proton Therapy Systems
  • Modular Proton Therapy Systems

By Component

  • Accelerators
    • Cyclotrons
    • Synchrotrons
    • Synchrocyclotrons
    • Linear Accelerators (Linacs)
  • Beam Delivery Systems
    • Nozzle Systems
    • Beam Transport Magnets
  • Imaging and Monitoring Systems
    • CT/MRI/PET Integration
    • Motion Management Systems
  • Treatment Planning Systems
  • Patient Positioning Systems
  • Shielding and Enclosures

By Region

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa (MEA)

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Frequently Asked Questions

The global proton therapy market size was accounted at USD 572.5 billion in 2024 and it is expected to reach around USD 1995.62 billion by 2034.

The global proton therapy market is poised to grow at a CAGR of 13.30% from 2025 to 2034.

The major players operating in the proton therapy market are IBA Worldwide, Varian medical systems, Inc, HItachi, Ltd, Mevion medical systems, Sumitomo Heavy Industries, Ltd, Optivus Proton Therapy, Advanced Oncotherapy plc, ProTom International, Mitsubishi Corporation, ProNova Solutions LLC, Sun Nuclear Corporation, Provision Healthcare, Koninklijke Philips N.V, Elekta AB, GE Healthcare, Best Cyclotron Systems, Ray Search Laboratories, Permedics

Increasing cancer disorder among the population, rising healthcare spending in developing nations, increased advanced technologies, these are driving factor of the proton therapy market.

North America region will lead the global proton therapy market during the forecast period 2025 to 2034.

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Sanket Gokhale is one of the key authors contributing to the high-quality, actionable insights that define our market research reports. Sanket holds an MBA with a specialization in Healthcare Management, coupled with a Bachelor’s degree in Pharmacy. With over 5 years of experience in market research, Sanket has cultivated a deep understanding of the healthcare sector, from pharmaceutical innovations to healthcare infrastructure and policy shifts. His diverse educational background and hands-on experience

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