FUJIFILM and HORIBA Launch Advanced Inline Raman System for Biopharmaceutical Manufacturing
Published: 03 Jul 2026
Author: Vidyesh Swar
FUJIFILM Corporation and HORIBA, Ltd. have announced the world's first co-development of a high-sensitivity Inline Raman Measurement System, which will further enable the real-time monitoring of biopharmaceutical manufacturing processes. Its novel system is designed to continuously monitor vital process parameters, including cell culture and purification, thereby allowing manufacturers to gain real-time process information.
Advancing Process Spectroscopy in Biopharmaceutical Manufacturing
The project has successfully developed a process-knowing spectroscopy system, which was constructed by FUJIFILM and HORIBA to measure online and automatically various key parameters of the process. The inline Raman system will be able to produce analytical data in real-time, enabling Process Analytical Technology programs that will optimize cell growth and purification with improved efficiencies, and enhance overall process performance.
Continuous monitoring brings uniformity in production; less risk in operations; faster decisions made without compromising the high quality standards required for production. It is a global phenomenon of the growth of biologics and advanced therapeutics, which is compelling manufacturers to change their analytical technologies of manufacturing, manufacturing consistency, regulatory compliance, and scalability of the product.
According to Precedence Research, the Process Spectroscopy Market size was calculated at USD 25.48 billion in 2025 and is predicted to increase from USD 28.26 billion in 2026 to approximately USD 71.70 billion by 2035, expanding at a CAGR of 10.90% from 2026 to 2035 as pharmaceutical and biotechnology companies increasingly invest in real-time analytical technologies, automated manufacturing, and digital process optimization.
Industry Impact and Outlook
A new inline Raman measurement system is a good example to show the increasing value and importance of an accurate, spectroscopic measurement system in the biopharmaceutical manufacturing environment. Time-of-analytics-based technologies are rapidly becoming crucial to increase manufacturing efficiency and reduce manufacturing cost, and there is an increasing need for intelligent manufacturing and real-time knowledge of quality.
The partnership reflects a trend across the industry to extend the use of smart monitoring systems into biologics manufacturing to aid in improving product yield and product quality to facilitate quicker commercialisation of novel therapies.