Live Biotherapeutic Products and Microbiome CDMO Market Revenue to Attain USD 1,075.98 Mn by 2033

11 Jun 2025

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Table of Content

1. Live Biotherapeutic Products and Microbiome CDMO Market Revenue and Trends 2025 to 2033 2. How are Advances in Microbiome Research and Technology Impacting Market Growth? 3. Segment Outlook 4. Regional Insights 5. Live Biotherapeutic Products and Microbiome CDMO Market Coverage 6. Live Biotherapeutic Products and Microbiome CDMO Market Key Players

Live Biotherapeutic Products and Microbiome CDMO Market Revenue and Trends 2025 to 2033

The global live biotherapeutic products and microbiome CDMO market revenue reached USD 76.77 million in 2025 and is predicted to attain around USD 1,075.98 million by 2033 with a CAGR of 39.10%. The growth of the live biotherapeutic product and microbiome market is driven by rising chronic disease prevalence.

How are Advances in Microbiome Research and Technology Impacting Market Growth?

The live biotherapeutic products and microbiome CDMO market is experiencing rapid growth, driven by several factors. Firstly, the increasing interest in microbiome-associated therapies, stemming from research and development. Secondly, the rising awareness among people about gut health and benefits of biotherapeutic products to treat various conditions like metabolic syndromes, immune regulation, and neurological health. Advances in microbiome R&D are opening up new growth avenues. Advancements in areas such as formulations and delivery systems encourage CDMOs to improve the efficacy of live biotherapeutic products.

Additionally, the increasing prevalence of chronic diseases and antibiotic-resistant infections is driving the demand for innovative treatments, including microbiome-focused approaches. The willingness of drug developers to outsource product development and manufacturing to CDMOs, particularly those with expertise in complex microbial formulations under GMP conditions, further contributes to this dynamic market environment. These factors are creating a landscape where innovation and partnerships are likely to thrive, leading to sustained high-value growth in the live biotherapeutics and microbiome CDMO markets.

Segment Outlook

• By application, the C. difficile segment held the largest revenue share of the market in 2024. This is mainly due to the increase in the prevalence of C. difficile infections, creating the need for biotherapeutic products. Live biotherapeutic products have proven effective in treating gastrointestinal diseases caused by C. difficile infection.

Regional Insights

North America dominated the market in 2024. This is mainly due to its well-established biotech industry, significant investments in R&D, and appropriate regulatory frameworks. The presence of a large number of CDMOs further supports market growth in the region. Europe is the second largest market with more investment being made in gut-health and an increase in the number of clinical trials targeting microbiomes. The market in Asia Pacific is expected to expand at a rapid pace due to elevated health care spending in China and India, high demand for precision medicine, and rising partnerships between CDMO and biopharmaceutical companies.

Live Biotherapeutic Products and Microbiome CDMO Market Coverage

Recent Development

• In June 2025, WuXi Biologics announced a groundbreaking for a new microbial manufacturing campus in Chengdu, which includes a 15,000 L fermenter, dual-chamber lyophilizer, and vial-filling line—the first in China—with a production capacity of more than 10 million vials per year. 
  (Source- https://www.wuxibiologics.com)

Live Biotherapeutic Products and Microbiome CDMO Market Key Players

• Arrant Bio
• 4D Pharma
• Cerbios
• Biose Industrie
• Assembly Biosciences, Inc.
• Wacker Chemie AG
• Quay Pharmaceuticals
• NIZO
• Lonza
• Inpac Probiotics

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