Bioreactors Market Size, Share, and Trends 2024 to 2034

Bioreactors Market (By Product Type: Single Use, Reusable; By Cell: Mammalian Cells, Bacterial Cells, Yeast Cells, Others; By Molecule: Monoclonal Antibodies, Vaccines, Recombinant Proteins, Stem Cells, Gene Therapy, Others; By Usage: Developmental, Preclinical & Clinical, Commercial Production; By End-Use) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2023-2032

  • Last Updated : January 2023
  • Report Code : 2569
  • Category : Healthcare

The global bioreactors market size was evaluated at USD 9.3 billion in 2022 and it is expected to hold around USD 30.42 billion by 2032, growing at a CAGR of 12.58% between 2023 and 2032.

Bioreactors Market Size 2023 To 2032 - Precedence Statistics

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Key Takeaways

  • Based on geography, the North American region registered a significant growth rate.
  • Based on product type, The reusable bioreactors segment is predicted to capture major revenue and is estimated more than 76%.
  • Based on end-use, the biopharmaceutical (biopharma) manufacturers segment will have a maximum market share and generated more than 43%. 
  • Based on cell, The segment of mammalian cells will capture major revenue.
  • Based on the molecule, The vaccine segment will dominate the global market and will grow remarkably from 2023 to 2032.
  • Based on usage, the developmental, preclinical & clinical segment increase significantly from 2023 to 2032.

Bioreactors are the vessels and the manufacturing devices which are used for the biological reactions of different organisms like bacteria and yeast are grown or even animal cells are grown when these are subjected to the proper environment. The growth of this cell is maintained due to the sustainable environment in the formation of a product. 

The biotechnology industry and the pharmaceutical industry makes use of bioreactors to produce biological products, antibodies and even vaccines. To subject or to cultivate different organisms' industrial processes also make use of bioreactors which are used for treating chronic diseases. Many pharmaceutical products make use of bioreactors in controlled conditions.

Growth Factors

Monoclonal antibiotics have a great demand in various nations across the globe, due to which the bioreactors market is expected to see significant growth during the forecast. As the amount of funds received through government organizations and private organizations have grown in recent times in order to develop different types of vaccines for various diseases, the market will show subsequent growth. Single-use bioreactors also have a good demand, and it will generate a large amount of revenue in the long run. 

The Pharmaceutical industry and the biotechnology sector make maximum use of bioreactors. As both of these industries are developing and increasing, the bioreactors market is also expected to grow. Technological development is also expected to play an instrumental role in the use of advanced bioreactors and various equipment of advanced nature. Cultivation parameters can be monitored through the help of screens, and all of these advanced features will lead to the growth of the market. Quality data can be collected and gathered through the use of such developments, and it also leads to less human intervention.

Advanced bioreactors are receiving more funds, and the market players are also engaged in the manufacturing of these bioreactors. Constant research and development activities in the field of bioreactors will help in the growth of the market. Clinical trials and preclinical trials have increased. Research and development activities for microbial applications and cell culture have also grown in recent times. All of these factors will lead to the growth of the market during the forecast period. 

As there has been an increase in different types of chronic diseases across the globe like diabetes, cancer and cardiovascular diseases, the need for various therapies associated with all of these diseases will lead to the growth of the bioreactors market. The introduction of novel therapies for treating cancer will also create more demand for bioreactors.

  • The outbreak of the COVID-19 pandemic led to increased use of bioreactors.
  • As there was a growing demand for effective therapeutics, the market for bioreactors grew drastically. The manufacturing of preventive vaccines also needed a large number of bioreactors.
  • Different pharmaceutical industries were engaged in the manufacturing of vaccines in order to meet the demands of the population due to which the capacities of their manufacturing units were also increased, and the purchases of bioreactors had also increased.
  • Personalized medicines are in great demand and the use of these medicines will create more demand for bioreactors.
  • Technological advancements will help in generating greater revenues.
  • The biotechnology industry and the pharmaceutical industry are showing rapid growth due to which the bioreactors market will grow significantly.

Bioreactors Market Scope

Report Coverage Details
Market Size in 2023 USD 10.47 Billion
Market Size by 2032 USD 30.42 Billion
Growth Rate from 2023 to 2032 CAGR of 12.58%
Base Year 2022
Forecast Period 2023 to 2032
Segments Covered By Product Type, By Cell, By Molecule, By Usage and By End-Use
Regions Covered North America, Europe, Asia-Pacific, Latin America and Middle East & Africa


Bioreactors Market Dynamics

Key Market Drivers

Development of preventive vaccines - In order to manufacture different types of vaccines that play a significant role in preventing various diseases will lead to the growth of the market. In recent times after the outbreak of the COVID-19 pandemic, the demand for COVID-19 vaccines had increased across the globe and the need for bioreactors of the clinical stage had also increased. Bioreactors were adopted on a large scale in various pharmaceutical industries for various procedures.

Organism cultivation - Bioreactors act as the apparatus for the cultivation of organisms like yeast, bacteria, animal cells and mammalian cells. All these are done in a controlled environment. Industrial processes also make use of bioreactors for the manufacturing of pharmaceutical products like monoclonal antibodies and vaccines. Biologicals are produced in a commercial way, and this also has a good application for bioreactors, due to which the adoption of this product will be more in the healthcare sector.

Technological advancements - In the coming years, market growth will be augmented by constant advancements in the features of the bioreactors and the processing of the bioreactors. Proactive involvement of the manufacturers of various nations in developing advanced technology which shall provide cost-effective bioreactors and help in the manufacturing of large-scale products, will lead to the growth of the market. There are many benefits associated with the use of advanced bioreactors, and all of these benefits will generate good revenue.

Processing large volumes of products and increasing the volume as much as possible with the use of advanced bioreactors. It enhances efficiency and it also simplifies the procedure. Single-use bioreactors have a greater adoption as this technology is better and provides good benefits for operations.

Key Market Challenges

Low-capacity bioreactors - Many different types of bioreactors are available in the market, and the single-use ones have less capacity in any process and procedure, and this happens to pose a challenge in the growth of the market.

Product Type Insights

The reusable bioreactors segment is expected to generate maximum revenue which is estimated to be about 76%, as most organizations prefer reusable bioreactors and the growth in the adoption of these bioreactors for bulk manufacturing of products in the healthcare industry will increase revenue size. These bioreactors have a higher volume of capacity and better scalability which will eventually accelerate the market expansion. 

Bioreactors Market Share, By Product Type, 2022 (%) - Precedence Statistics

The demand for single-use bioreactors will be more very flexible, and easy and quick deployment is needed. Cross-contamination is prevented with the use of single-use bioreactors, and as these bioreactors enhance safety, the market demand for single-use bioreactors will also grow. Single-use bioreactors are less expensive as compared to traditional bioreactors, and the implementation cost of these bioreactors is less.

Cell Insights

Depending on the cells, the bioreactors market can be segmented into yeast cells, Mammalian cells, bacterial cells and a few other cells. The segment of mammalian cells will generate maximum revenue. The demand for bioreactors will be more due to the increased use of these cells in the commercial production and development of various vaccines and proteins that are used in therapeutic procedures. Viral analogs are also generated with the help of these cells, which are extremely significant for regenerative medicines, and this will be instrumental in increasing the revenue size of the bioreactors market.

Molecule Insights

The vaccine segment will dominate the market and will grow significantly in the coming years. Recently, the demand for COVID vaccines has increased drastically, due to which significant growth has been registered. Various disorders of a chronic nature and rare disorders have significantly increased the demand for bioreactors. Research and development activities conducted for developing different vaccines will accelerate market growth. Activity associated with the development of vaccines will stimulate market expansion. 

Usage Insights

The need for bioreactors in clinical trials and preclinical trials for developing various drugs will increase significantly during the forecast period. Bioreactors are used in the clinical segments, preclinical segments,s and developmental segments. Growth opportunities will be provided due to a growing number of cases of chronic diseases. 

Rare diseases have also increased in recent times, and the development of drugs for such diseases will create more demand for bioreactors. Bioreactors of smaller scale will also have good demand in the market in order to develop new drugs that could treat rare diseases.

End User Insights

The biopharma manufacturer segment will have a larger market share which is estimated to be about 43%. Advanced technologies are adopted on a large scale in order to simplify manufacturing procedures due to which the need for such products will grow. Forthcoming years will see a maximum application of bioreactors in manufacturing and developing complex molecules like proteins and nucleic acids. As the number of pharmaceutical industries and biotechnology industries are going, the demand for 

bioreactors will grow significantly. In developing nations, the capacity for manufacturing biopharmaceutical products is also increasing. The healthcare industry is expected to adopt more and more bioreactors and innovative products for various procedures. Intensive procedures adopted in modern times require the higher transfer of oxygen and efficient removal of carbon dioxide due to which the advanced by the actors will have a greater demand during the forecast period.

Regional Insights

Significant growth rate to be registered in the North American region for the bioreactors industry. Prominent manufacturers are present in the North American region due to which the market growth will be substantial. The number of patients suffering with chronic diseases have also grown in recent times and the geriatric population is also increasing, due to which the demand for bioreactors will be more in the North American region. 

The amount of expenditure made on research and development activities is also increasing in the North American region, and this will drive market growth in the forecast period. The facilities provided for conducting research and development activities are also favourable and it will show a significant increase. Such activities are supported by government investments as the demand for various vaccines has increased. 

The development of the same after the outbreak of the COVID-19 pandemic has also grown. Good opportunities for the growth of the market will be provided by the North American region in the coming years.

Recent Developments

  • The biotechnology company Freeline entered in a partnership with another organization, Pall corporation in the year 2019. This partnership was formed for the implementation of the bioreactor system of iCELLis with Freeline organization's AAV platform of manufacturing.
  • Sartorius Stedim biotech into a partnership with Repligen corporation in 2019 for the introduction of the next Gen bioreactors that are perfusion enabled.

Bioreactors Market Companies

  • GE Healthcare
  • Merck KGaA
  • Eppendorf AG
  • Sartorius AG
  • Thermo Fisher Scientific Inc.
  • BBI-Biotech GmbH
  • Bioengineering AG
  • Danaher Corporation
  • Getinge
  • Infos HT
  • Solaris Biotech Solutions

Segments Covered in the Report

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By Product Type

  • Single-Use 
  • Reusable

By Cell

  • Mammalian Cells
  • Bacterial Cells
  • Yeast Cells
  • Others

By Molecule

  • Monoclonal Antibodies
  • Vaccines
  • Recombinant Proteins
  • Stem Cells
  • Gene Therapy
  • Others

By Usage

  • Developmental, Preclinical & Clinical
  • Commercial Production

By End-Use

  • Research and Development (R&D) Organizations
  • Biopharmaceutical (biopharma) Manufacturers
  • Contract Manufacturing Organizations (CMOS)

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • The Middle East and Africa

Frequently Asked Questions

The global bioreactors market size was accounted at USD 9.3 billion in 2022 and it is expected to reach around USD 30.42 billion by 2032.

The global bioreactors market is poised to grow at a CAGR of 12.58% from 2023 to 2032.

The major players operating in the bioreactors market are GE Healthcare, Merck KGaA, Eppendorf AG, Sartorius AG, Thermo Fisher Scientific Inc., BBI-Biotech GmbH, Bioengineering AG, Danaher Corporation, Getinge, Infos HT, Solaris Biotech Solutions and Others.

The driving factors of the bioreactors market are the development of preventive vaccines, organism cultivation and increasing technological advancements.

North America region will lead the global bioreactors market during the forecast period 2023 to 2032.

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