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Oncology Proteomics Market Size, Share and Trends 2025 to 2034

The oncology proteomics market is set to grow from 2034, driven by rising cancer prevalence, biomarker research, and demand for targeted therapies. The market sizing and forecasts are revenue-based (USD Million/Billion), with 2024 as the base year.

  • Last Updated : 06 May 2025
  • Report Code : 6039
  • Category : Healthcare

Oncology Proteomics Market Size and Forecast 2025 to 2034

The oncology proteomics advances cancer research and precision medicine through biomarker discovery, protein analysis, and targeted therapies for improved patient outcomes. The growth of the market is driven by the rising burden of cancer worldwide and the increasing demand for personalized medicine.

Oncology Proteomics Market Size 2025 to 2034

Oncology Proteomics Market Key Takeaways

  • North America dominated the oncology proteomics market in 2024.
  • Asia Pacific is expected to grow at the fastest rate in the upcoming period.
  • By component, the reagents & consumables segment dominated the market in 2024.
  • By component, the software & services segment is expected to expand at the fastest rate during the forecast period.
  • By application, the cancer biomarker discovery & validation segment led the market in 2024.
  • By application, the oncology drug discovery & development segment is likely to grow at the fastest rate between 2025 and 2034.
  • By technology, the mass spectrometry-based oncology proteomics segment held the dominant share of the market in 2024.
  • By technology, the AI-driven proteomics for cancer drug targeting segment is projected to expand at the highest CAGR in the coming years.
  • By end-use, the pharmaceutical & biotechnology companies focused on oncology segment dominated the market in 2024.
  • By end-use, the contract research organizations (CROs) specializing in cancer proteomics segment is anticipated to grow at the fastest rate during the projection period.

How does AI Impact the Oncology Proteomics Market?

Artificial Intelligence (AI) is transforming how clinicians and researchers interpret complex protein interactions and biomarkers. AI-driven solutions enable rapid analysis of large proteomic datasets more precisely, speeding up progress in cancer diagnostics, personalized treatments, and drug discovery. AI and machine learning ML enable researchers to understand intricate patterns within the vast proteomic datasets. This significantly helps them identify biomarkers associated with a particular subtype of cancer. There are different AI-driven platforms, such as OncoDEEP, which uses molecular profiling to analyze proteomics datasets and guide therapy decisions, improving the outcomes of cancer patients. AI-driven platforms lead to precision oncology, where they correlate protein expression patterns with patients' reactions to different treatments.

Market Overview

The oncology proteomics market is experiencing rapid growth due to the rising demand for personalized cancer therapies, precision medicine, and targeted therapies. Oncology proteomics facilitates the analysis of cancer proteome, expression of the protein, and mapping of drug interaction, all of which are important factors for developing targeted therapies. Its goal is to identify novel tumor-specific proteins that serve as prognostic and diagnostic indicators. This market comprises a broad range of components, such as reagents, consumables, services, and software. Mass spectroscopy and liquid chromatography-mass spectroscopy are important tools for cancer biomarker discovery and drug development. Increasing integration of advanced technologies is revolutionizing the role of proteomics in oncology. Major evolving techniques like single-cell proteomics are allowing researchers to study heterogeneity in unprecedented detail, offering deep insights into cancer biology. Major pharmaceutical organizations leverage proteomics to optimize the pipeline of drug discovery and targeted therapy development. Many research institutions focus on unraveling cancer biology through conducting proteomic profiling of the microenvironment of cancer.

Oncology Proteomics Market Growth Factors

  • Increasing government investments in cancer research and development activities boost the growth of the market.
  • Ongoing advancements in proteomics technology strengthen the capability to analyze large-scale data of proteomics, leading to enhanced diagnostics and treatment strategies.
  • The growing demand for targeted therapies is driving the proteomics adoption. Proteomics helps in data analysis, enhancing the identification of therapeutic targets and drug resistance mechanisms in cancer.

Market Scope

Report Coverage Details
Dominated Region North America
Fastest Growing Market Asia Pacific
Base Year 2024
Forecast Period 2025 to 2034
Segments Covered Component, Application, Technology, End Use, and Region
Regions Covered North America, Europe, Asia-Pacific, Latin America and Middle East & Africa

Market Dynamics

Drivers

Growth of Genomics and Proteomics Technologies

Increasing advancements in genomics and proteomics technologies are driving the growth of the oncology proteomics market. Genomics and proteomics have revolutionized cancer treatment and diagnostics strategies. These technologies enable researchers and clinicians to analyze the molecular profile of cancer with unprecedented precision, which leads to highly effective and targeted therapies. Through the incorporation of genomic sequencing with proteomic analysis, researchers gain huge insight into the protein-level and genetic alterations in tumors, allowing more personalized approaches to the treatment. Proteomics studies and genomic sequencing have significantly increased cancer profiling, providing a comprehensive understanding related to the molecular changes that drive cancer progression.

Restraint

Proteomics Tools and Technology are Expensive

The high costs associated with proteomics tools and technologies hamper the growth of the oncology proteomics market. Research on proteomics requires modern tools like mass spectrometers, bioinformatics software, and chromatography systems, all of which are costlier. This cost factor limits the adoption of advanced proteomics technology, particularly among small and medium-size enterprises (SMEs), research laboratories, and academic institutions with limited budgets.

Opportunity

Development of Precision and Personalized Medicine

The development of precision medicine creates immense opportunities in the oncology proteomics market. Precision medicine is transforming cancer care and diagnosis, enhancing patient outcomes. There is a rising demand for personalized medicine, which opens up new avenues for market growth. Personalized medicine modifies treatment based on genetic makeup and protein expression profiles of individual patients. This improves the effectiveness of therapy and lowers adverse events by selecting the most suitable treatment options. Proteomic technology also plays a significant role in the early diagnosis and detection of cancer by detecting unique protein signatures associated with tumors.

Component Insights

The reagents & consumables segment dominated the oncology proteomics market with the largest share in 2024. This is mainly due to the increased number of cancer research and proteomic studies. Reagents & consumption play a key role in proteomic experiments, serving various functions throughout the experimental workflow. Antibodies and reagents facilitate sample preparation, protein quantification, and progression and onset of tumors, leading to early diagnosis of tumor. Also, reagents and consumables are applicable in the processes of drug synthesis for the treatment of cancer.

The software & services segment is expected to expand at the fastest rate during the forecast period. Software is an important tool in proteomic experiments, which helps in the analysis, interpretation, and management of vast amounts of complex data. It helps in identifying biological changes in cancer. Based on advanced software and services technology, important data like protein targets and signaling pathways related to the metastasis and growth of cancer cells can be recognized. Software and services predict a patient's prognosis by observing alterations in proteins that act as existence factors after cancer therapies. The increasing need for data management solutions is likely to drive the segment’s growth.

Application Insights

The cancer biomarker discovery & validation segment led the oncology proteomics market in 2024. This is mainly due to the increased need for early cancer detection. Proteomics enables the identification of protein biomarkers for early cancer detection. Biomarkers also play a crucial role in monitoring cancer progression and the response of cancer cells to treatment. Recent approaches incorporating proteomics with other technologies like imaging are unraveling the complexity of the proteomics changes in cancer and are producing data that are thought to be more representative of the in vivo condition and tumor environment.

The oncology drug discovery & development segment is likely to grow at the fastest rate over the forecast period as proteomic technologies are crucial for drug discovery. These technologies, comprising protein-protein interaction mapping, reverse phase protein arrays, and mass spectrometry, provide complementary data for drug development. Proteomics is employed to detect the properties of drug-resistant cancer cells and identify targets that overcome drug resistance that develops throughout the treatment of anticancer. Proteomics helps identify and validate potential drug targets by analyzing protein expression and modification in cancer cells.

Technology Insights

The mass spectrometry-based oncology proteomics segment held the largest share of the oncology proteomics market in 2024 due to its reproducibility, repeatability, and wide dynamic range, allowing excellent and precise protein quantification in many biological samples, particularly in biomarker research. It identifies replacements of single amino acids in proteins and is applicable to quantify single proteins in mixtures. By using a class-specific isolation process, quantitative assays for protein isoforms can be developed without the requirement for an antibody. Mass spectrometry offers high sensitivity and specificity for protein identification and quantification, enabling the detection of subtle changes in protein expression.

The AI-driven proteomics for cancer drug targeting segment is projected to expand at the highest CAGR in the coming years. AI can identify novel therapeutic targets, assess the sensitivity and resistance of anticancer drugs, monitor the evolution and recurrence of the tumor, and predict the prognosis and existence of cancer patients. AI is a modern technology that detects new anticancer targets and helps in the discovery of novel drugs. AI can analyze vast and complex datasets of proteomics, including protein expression and protein-protein interaction.

End-Use Insights

The pharmaceutical & biotechnology companies focused on oncology segment dominated the oncology proteomics market in 2024. This is mainly due to the increased investment by these companies in novel drug development. Oncology proteomics plays a crucial role in drug discovery as it identifies potential drug targets, understands drug mechanisms, and predicts drug response. Cancer drug development relies on proteomic techniques to detect potential biomarkers and mechanisms of action and to identify protein binding in the drugs. The increased demand for personalized medicine further bolstered segmental growth.

The contract research organizations (CROs) specializing in cancer proteomics segment is anticipated to grow at the fastest rate during the projection period. This is mainly due to the rising outsourcing of drug development. CROs provide oncology and hematology expertise with a focus on advanced trials in the spectrum of cancer therapeutics, from targeted therapies and immuno-oncology to cell and gene therapies. CROs offer cost-effective services for pharmaceutical & biotechnology companies, enabling early quick development of therapeutics.

Regional Insights

North America dominated the oncology proteomics market by capturing the largest share in 2024. This is mainly due to the increased cancer burden across the region. The region has a well-established research infrastructure, fostering innovation and supporting proteomics research. Recent advancements in the field of oncology have significantly enhanced patient outcomes. Significant investments in R&D aimed at developing lifesaving and life-changing treatments further bolstered the growth of the market in the region.

The U.S. is a major contributor to the North American oncology proteomics market. The rising cancer prevalence and advancements in cancer screening and treatments are propelling the growth of the market. According to the National Institutes of Health (NIH), about 2,001,140 new cancer cases and 611,720 cancer deaths occurred in the U.S. in 2024. There is a high demand for personalized therapies. Rising investments in drug development further support market growth. Canada also plays a major role in the market. There is a strong emphasis on cancer research to accelerate the development of novel therapies. The Canadian Cancer Society invests heavily in cancer research, supporting market growth.

Asia Pacific is anticipated to witness the fastest growth during the forecast period. The growth of the market in Asia Pacific can be attributed to the increasing number of cancer cases. Cancer incidence and mortality are significant public health concerns in the region, prompting research efforts to identify novel therapies. Governments around the region are investing heavily in cancer research. In addition, there is a strong emphasis on developing targeted therapy, new immunotherapies, and precision medicine, in which proteomics plays a crucial role.

  • For instance, in October 2024, ACT Genomics Co. Limited and mProbe Taiwan Inc. signed a Memorandum of Understanding (MOU) to collaborate on advancing precision medicine across Asia. The agreement aims to combine the unique expertise of both companies to provide cutting-edge diagnostic solutions to healthcare providers in the region.

In China, the burden of cancer has been growing steadily. The country boasts some leading research institutes, supporting cancer research. There is high awareness regarding cancer prevention among the people, boosting the demand for proteomics-based diagnosis technologies. Mass spectrometry technology has become an indispensable means of advanced analytical techniques for cancer treatment.  China's thriving biotechnology and pharmaceutical industries are investing in high-throughput proteomics platforms tailored for cancer diagnostics and research.

  • For instance, in 2023, BGI, a Chinese genomics company, pioneered the field of multi-omics and provided modern proteomics and bioinformatics technology to help research. 

India is emerging as a powerhouse in oncology proteomics. With the increasing prevalence of cancer, the Indian government is investing in novel drug discovery and development. The growing life sciences sector in India is also emerging as a leading destination for major clinical trials, manufacturing activities, and contract research, which is driving the oncology proteomics market.

  • In April 2024, Nagpur-based biotech startup ErlySign achieved a significant milestone in cancer detection with approval from India's CDSCO for its active salivary biomarker study aimed at early cancer detection. The approval follows a rigorous year-long validation and investigation of data from 150 test samples, enabling ErlySign to commence large-scale clinical trials.

Oncology Proteomics Market Companies

Oncology Proteomics Market Companies
  • Illumina, Inc.
  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • Thermo Fisher Scientific, Inc.
  • Bruker Corporation
  • F. Hoffmann-La Roche Ltd.
  • Waters Corporation
  • Merck KGaA
  • Danaher
  • Standard BioTools Inc.

Recent Developments

  • In April 2025, PredxBio, a pioneer in AI-powered spatial biomarker discovery, announced a strategic partnership with Hamamatsu Photonics K.K. The partnership unites Hamamatsu's advanced MoxiePlex multiplex immunofluorescence imaging system with PredxBio's SpaceIQ spatial analytics platform to deliver an integrated workflow tailored to basic and translational research tailored to immuno-oncology.
  • In January 2025, IMAC Holdings, Inc. launched Ignite Proteomics LLC, its novel subsidiary dedicated to supporting doctors in selecting the most effective cancer treatments based on protein-level insights. This move addresses a growing requirement for better, faster ways to personalize therapy in breast cancer and beyond.
  • In July 2024, Thermo Fisher Scientific completed its acquisition of Olink Holding, a Sweden-based provider of next-generation proteomics solutions, in a transaction that values Olink at approximately $3.1 billion.

Segments Covered in the Report

By Component

  • Instruments
    • Mass Spectrometry (MS) for Oncology Drug Development
    • Liquid Chromatography-Mass Spectrometry (LC-MS) for Cancer Biomarker Discovery 
    • Capillary Electrophoresis for Tumor Proteome Analysis 
    • Microarrays for Cancer Protein Expression Studies 
    • Surface Plasmon Resonance (SPR) for Drug-Protein Interaction in Oncology
    • Spatial Proteomics Imaging Systems for Tumor Microenvironment Analysis 
  • Reagents & Consumables
    • Immunoassay Reagents for Cancer Detection
    • Protein Microarray Reagents for Tumor Profiling
    • Chromatography Reagents for Cancer Biomarker Separation
  • Software & Services
    • AI-Based Oncology Proteomics Analysis Tools 
    • Cloud-Based Platforms for Cancer Proteomics Data 
    • Bioinformatics for Cancer Drug Discovery & Precision Oncology 
    • Spatial Proteomics Data Analytics Platforms 

By Application

  • Cancer Biomarker Discovery & Validation
    • Identifying Novel Cancer Biomarkers
    • Proteomic Profiling of Tumor Microenvironment
    • Non-Invasive Blood-Based Proteomic Biomarkers (Liquid Biopsy)
    • Spatially Resolved Proteomics for Biomarker Localization
  • Oncology Drug Discovery & Development
    • Target Identification & Validation for Cancer Therapeutics
    • Proteomic Insights into Drug Resistance in Cancer Cells
    • Pharmacoproteomics for Personalized Oncology Therapies
    • Companion Diagnostics for Cancer Therapy
    • Proteomic-Based Predictive Biomarkers for Targeted Cancer Therapy
    • Proteomic Assays for Immuno-Oncology Treatment Response
  • Immuno-Oncology & Proteomics
    • Proteomic Mapping of Tumor Immune Microenvironment
    • Checkpoint Inhibitor Response Prediction Using Proteomics
    • CAR-T Therapy Biomarker Analysis Using Proteomics
    • Spatial Proteomics for Immune Cell Distribution in Tumors

By Technology

  • Mass Spectrometry-Based Oncology Proteomics
  • Chromatography-Based Proteomics for Cancer Drug Analysis
  • AI-Driven Proteomics for Cancer Drug Targeting
  • Single-Cell Proteomics for Tumor Heterogeneity Analysis
  • Protein Microarrays for High-Throughput Cancer Biomarker Screening
  • Spatial Proteomics for Tumor Microenvironment Analysis
  • Multiplexed Imaging-Based Spatial Proteomics for Cancer Research
  • Spatially-driven Biomarker Discovery for Immuno-Oncology

By End-Use

  • Pharmaceutical & Biotechnology Companies Focused on Oncology
  • Oncology Research Institutions & Hospitals
  • Contract Research Organizations (CROs) Specializing in Cancer Proteomics
  • Oncology-Specific Clinical Diagnostic Laboratory

By Region

  • North America
  • Europe
  • Asia Pacific
  • Middle East & Africa
  • Latin America

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Frequently Asked Questions

The major players operating in the oncology proteomics market are Illumina, Inc., Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Inc., Bruker Corporation, F. Hoffmann-La Roche Ltd., Waters Corporation, Merck KGaA, Danaher, Standard BioTools Inc., and Others.

The driving factors of the oncology proteomics market are the rising burden of cancer worldwide and the increasing demand for personalized medicine.

North America region will lead the global oncology proteomics market during the forecast period 2025 to 2034.

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