Folate Market Size, Share, and Trends 2025 to 2034

Folate Market Size and Forecast 2025 to 2034

The global folate market size was estimated at USD 984.11 million in 2024 and is anticipated to reach around USD 1787.55 million by 2034, expanding at a CAGR of 6.15% from 2025 to 2034.

Folate Market Key Takeaway

• North America led the folate market with the largest market share of 41% in 2024.
• By type, the 5-MTHF calcium salt segment has held a significant market share in 2024.
• By End User, The pharmaceuticals and nutraceuticals segment accounted the biggest market share in 2024.

Impact of AI on the Folate Market

The integration of AI plays a crucial role as it helps to discover new research insights. AI algorithms have the ability to predict how different compounds interact, which helps streamline R&D processes. AI also help in developing personalized nutrition by analyzing individual patients' dietary habits and health conditions. Moreover, it helps in the quality control process, leading to enhanced quality of folate supplements.

U.S. Folate Market Size and Growth 2025 to 2034

The U.S. folate market size was evaluated at USD 302.61 million in 2024 and is predicted to be worth around USD 560.09 million by 2034, rising at a CAGR of 6.35% from 2025 to 2034.

The global research report offers market trends for folate products worldwide that is for North America, Europe, Asia-Pacific, Latin America, and Middle East and Africa. Geographically, folate market is conquered by North America owing to increasing demand from pharmaceutical and nutraceuticals industries for the end-user applications especially in the U.S. and Canada of the region. Asia Pacific is expected to register the fast growth rate, on account of increasing huge investment by key market players and growing adoption of the folate in the medical industries of the region. Also, increasing usage of the folate in the commercial industries for the various end user applications is driving growth of the industry in rest of the world.

Market Overview

Global folate industry is expected to continue its growth at significant CAGR during the forecast period owing to it increasing demand in pharmaceutical industries for endues applications. Further, advancements in the food service and food processing industry, is major factor anticipated to create lucrative growth opportunities for the key layers operating in the target sector. Growth of demand of nutritional food products and rising awareness for healthy food, has led, advancements in the food service and food processing industry which is creating opportunities folate market players worldwide. Further, due to COVID-19 Outbreak, the demand for vitamin supplements has risen exponentially, and the demand for folate is increasing rapidly. Hence the demand for the folate in the food industry will boost over the forecast period and will create growth opportunities for the key player's operating in the target sector.

Future of Global Folate Market

Key companies of the global industry such as Koninklijke DSM N.V and Merck are aiming towards business growth by implementing strategies like capacity expansion, innovative product launches and heavy investments in their production facilities that is expected to flourish the global folate market growth in the near future. This trend is expected to continue and will augment growth of the global folate industry in the next 10 years. Further, increasing end use applications of folate and rising medical industry are boosting growth of the folate industry in the coming years.

Folate Market Growth Factors

• Growing demand for folic acid in nutraceuticals and pharmaceuticals industries
• Health awareness among consumers
• Increasing adoption of folic acid for reduction of risk of neural tube birth defects and to treat kidney diseases

Market Scope

Value Chain Analysis

• Raw Material Procurement: Obtaining raw materials or intermediate compounds required for folate synthesis.

Key players: Fisher Scientific and Alfa Aesar

• Chemical Synthesis and Processing: Chemical reactions and purification steps in the synthesis of folate from precursors.
• Compound Formulation and Blending: Combining synthesized folate with excipients or nutrients in preparation for receiving the final product form, such as tablets or fortified mixtures.

Key Players: Abbott, DSM

• Quality Testing and Certification: Testing rigorously to verify that the folate product meets required specifications on purity, potency, and safety so regulatory bodies may grant that certification.

Key Players: U.S. Food and Drug Administration (FDA) and the European Food Safety Authority (EFSA)

• Packaging and Labeling: Placing the folate product in a container suitable for the product and labeling it with information on the nutrient, compliance, and related information.

Key Players: Nature Made, GNC

5-MTHF Calcium Salt Segment Is Projected To Dominate the Type Segment of Folate Market Revenue

The 5-MTHF calcium salt segment has held a significant market share in 2024. The 5-MTHF calcium salt folate segment is expected to dominate in terms of revenue over the forecast time frame and expected to continue its growth in the near future. However, the 5-MTHF glucosamine salt folate segment will expand at a substantial CAGR during the forecast time-frame owing to its increasing applications in the end-use sector in the globe.

Tablet Segment Is Projected To Dominate the Type Segment of Folate Market Revenue

On the basis of form, global market is segregated as gummies, capsules, lozenges, powder, tablets, and others. Tablet segment will dominate the target market in the near future owing to its increasing demand worldwide. Powder form is expected register maximum CAGR during the forecast time-frame.

Pharmaceuticals & Nutraceuticals Segment Is Projected To Dominate the End-use Segment of Folate Market Revenue

On the basis of end-use segment pharmaceuticals & nutraceuticals end-use segment is expected to dominate in terms of revenue over the forecast time frame. The growth is attributed to growing adoption of folates in the pharmaceuticals & nutraceuticals applications. Folate is commonly used in nutrition therapy for the treatment of nervous system, urinary and cardiovascular diseases in the pharmaceutical industry. Food & beverages segment will expand at a significant CAGR during the forecast time-frame.

Folate Market Companies

• Medicamen Biotech Ltd.
• Koninklijke DSM N.V
• Superior Supplement Manufacturing
• Gnosis SPA
• Seidler Chemical Co, Inc.
• Nutritional Supplement Manufacturers, Inc.
• Shandong Xinfa Pharmaceutical Co.
• AIE Pharmaceuticals, Inc.
• Hebei Jiheng Group Pharmacy Co Ltd.
• Changzhou
• Niutang Chemical Plant Co. Ltd.
• Jiangxi Tianxin Pharmaceutical Co. Ltd.
• BASF SE
• HEMA PHARMACEUTICALS PVT. LTD.
• Merck
• Gemini Pharmaceuticals, Inc.
• Emcure Pharmaceuticals Ltd.
• Nantong Changhai Food Additive

Key Market Developments

• In September 2025, Cadila Pharmaceuticals introduces Nu Nutridac, a clinically proven nutritional supplement for neurodegenerative and anxiety-related disorders, combining eight key ingredients for enhanced cognitive function and mood regulation.
  https://indiamedtoday.com
• In April 2025, Gnosis's Quatrefolic Fine Powder, patented for oily liquids, offers enhanced stability, bioavailability, and suspension capacity for innovative, consumer-friendly folate supplement formats.
  https://nutraceuticalbusinessreview.com

Segments Covered in the Report

By Type

• 5-MTHF Calcium Salt
• 5-MTHF Glucosamine Salt

By Form

• Tablets
• Capsules
• Powder
• Lozenges
• Gummies
• Others

By End-User

• Food & Beverages
• Pharmaceuticals & Nutraceuticals
• Agriculture & Feed
• Others

By Geography

• North America
• Asia Pacific
• Europe
• Latin America
• Middle East and Africa