Microcarriers Market Size, Share, and Trends 2024 to 2033

Microcarriers Market (By Consumables: Media & Reagents, Microcarrier Beads; By Application: Biopharmaceutical Production, Regenerative Medicine; By End-user: Pharmaceutical & Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations, Academic & Research Institutes) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2024-2033

  • Last Updated : June 2024
  • Report Code : 4530
  • Category : Healthcare

Microcarriers Market Size and Growth

The global microcarriers market size was USD 1.54 billion in 2023, calculated at USD 1.72 billion in 2024 and is expected to reach around USD 4.63 billion by 2033. The market is expanding at a solid CAGR of 11.63% over the forecast period 2024 to 2033. The microcarriers market is driven by the growing interest in vaccinations based on cells.

Microcarriers Market Size 2024 to 2033

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Microcarriers Market Key Takeaways

  • The North America microcarriers market size reached USD 650 million in 2023 and is expected to attain around USD 1,970 million by 2033, poised to grow at a CAGR of 11.72% between 2024 and 2033.
  • North America dominated market with the largest revenue share of 42% in 2023.
  • Asia-Pacific is observed to be the fastest growing in the microcarriers market during the forecast period.
  • By consumables, the microcarrier beads segment has held a major revenue share of 66% in 2023.
  • By application, the biopharmaceutical production segment has contributed more than 45% of revenue share in 2023.
  • By end-user, the pharmaceutical & biotechnology companies segment has generated the biggest revenue share of 45% in 2023.
  • By end-user, the academic & research institutes segment is the fastest growing in the microcarriers market during the forecast period.

U.S. Microcarriers Market Size and Growth 2024 to 2033

The U.S. microcarriers market size was exhibited at USD 450 million in 2023 and is projected to be worth around USD 1,390 million by 2033, poised to grow at a CAGR of 11.93% from 2024 to 2033.

U.S. Microcarriers Market Size 2024 to 2033

North America dominated in the microcarriers market in 2023. This is due to the increasing cell and gene therapy research in the region and the associations supporting it. Likewise, the American Society of Gene and cell Therapy is accountable for the funding of the research, and this society is forcing the biotechnology and biopharmaceutical companies to enhance their R&D. The United States microcarrier enterprise is dynamic and influential across the broader biotechnology and pharmaceutical landscape. It is well known for its innovation and technological improvements, and this enterprise plays a pivotal role in the cellular way of life, bioprocessing, and regenerative remedy applications.

Microcarriers Market Share, By Region, 2023 (%)

Asia-Pacific is the fastest growing in the microcarriers market during the forecast period. This region is owing to the growing numbers of key players and the rapidly increasing adoption of microcarriers. The technological advancements in the healthcare field and the growing need for cell therapies in the region are significant driving factors for the growth of the microcarriers market.

Market Overview

Microcarriers are microscopic particles or beads mainly utilized in bioreactors to culture adherent cells. They offer a greater surface area for cell development than conventional two-dimensional techniques. Biological materials can be coated on microcarriers to improve cell adhesion and proliferation. These materials include glass, dextran, and different types of polymers.

Microcarriers are essential to produce vaccinations, monoclonal antibodies, and other therapeutic proteins on a large scale. To address the increasing demand for biopharmaceuticals, they enable the effective growth of cells in bioreactors. Microcarriers can improve the uniformity and quality of cell cultures. Sustaining homogeneity in cell populations is essential for producing dependable biopharmaceutical products and can be achieved by offering a regulated growing environment for cells.

  • In April 2024, Kuraray Co., Ltd. evolved PVA hydrogel microcarriers for cell cultures required in regenerative medicine. The product was initiated in January 2024 in Japan and overseas, beginning in the United States.

Microcarriers Market Growth Factors

  • Microcarriers are increasingly used to develop cell therapies, including stem cells and cell-based vaccinations. Chronic illnesses such as cancer are becoming more common, and cell treatments may be able to treat them.
  • The creation of novel, better performing microcarriers to promote cell growth and functionality. The increasing use of 3D cell culture methods, which frequently use microcarriers.
  • Pharmaceutical and biotechnology businesses invest more in research and development to create new medications and therapies. Government support for using microcarriers in cell and gene therapy research has increased.
  • Commercializing cell therapies requires large-scale cell production in bioreactors, which microcarriers make possible. Compared to conventional approaches, they can lower manufacturing costs and provide greater control over cell growth conditions.

Microcarriers Market Scope

Report Coverage Details
Market Size by 2033 USD 4.63 Billion
Market Size in 2023 USD 1.54 Billion
Market Size in 2024 USD 1.72 Billion
Market Growth Rate from 2024 to 2033 CAGR of 11.63%
Largest Market North America
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered Consumables, Application, End-user, and Regions
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa

 

Microcarriers Market Dynamics

Driver

High demand of cell-based vaccines & therapeutics

Cell-based vaccinations frequently have greater efficacy than conventional egg-based vaccinations, mainly when targeting virus strains. Faster production of these vaccinations is significant since pandemics are emergencies when time is of the essence. Microcarriers make manufacturing more scalable and efficient by enabling the large-scale synthesis of cells needed for various treatments and vaccinations.

Production systems based on microcarriers are more cost-effective because of their efficiency and scalability. As a result, cell-based vaccinations and treatments become more affordable, increasing their accessibility. This drives towards the growth of the microcarriers market.

Restraint

High cost associated with serum-free media

Growth factors, specified components, and recombinant proteins are examples of raw ingredients frequently costly when utilized in serum-free media. Sophisticated manufacturing procedures are needed to produce serum-free media while upholding strict purity and quality standards. This often entails strict quality control procedures, aseptic processing, and sophisticated filtering.

The substantial initial cost of serum-free media for microcarrier cultures may deter companies from adopting them. This may reduce the industry's rate of adopting serum-free microcarrier technologies.

Opportunity

Huge investments for the development of innovative therapies

Research and development on cell and gene therapies is receiving significant financing from the governmental and corporate sectors. For instance, the possibility of cell and gene therapy to treat cancer, genetic disorders, and chronic diseases has attracted billions of dollars in investment to the global market. One important consideration is the creation of cells' scalability. The need for mass-producing therapeutic cells is met by microcarriers, which allow for the large-scale generation of cells in bioreactors.

Investments in biopharmaceutical facilities and technology increase the demand for sophisticated microcarrier solutions. Large sums of money are spent on bioprocess optimization, where microcarriers are essential. Improved microcarrier designs can lower expenses, increase yield, and ensure consistent quality in biopharmaceutical production.

Consumables Insights

The microcarrier beads segment dominated in the microcarriers market in 2023. Microcarrier beads can manufacture vast amounts of cells due to the large surface area they provide, which could be applied to produce, for example, viruses for vaccines. It is a convenient 3D model that is easily set up by simply mixing cells with microcarrier beads. The growing awareness about the applications of cell-based vaccines, growing regulatory approvals for cell-based vaccines, and a focus on commercial expansion of cell-based vaccines are contributing to the growth of the microcarriers market.

Application Insights

The biopharmaceutical production segment dominated in the microcarriers market in 2023. For most pathogens, such as the novel coronavirus, large-scale vaccine production is very important for global disease control and eradication because the high mutation rate of the virus might lead to a decrease in the protection offered by the vaccines. Moreover, research on the production and culture of virus vaccines, especially exploration at the laboratory scale, is urgently needed where the biopharmaceutical industries play a major role.

The versatility and scalability of microcarriers make them a preferred desire for production cell healing procedures, along with stem cell-based cures, immunotherapies, and tissue engineering applications. With increasingly more clinical trials and approvals for cellular therapies, the demand for microcarriers is surging.

The regenerative medicine segment shows a notable growth in the microcarriers market during the forecast period. Regenerative medicine is concentrated on developing and applying new treatments to heal tissues and organs and restore functions lost due to aging, damage, disease, or defects. Regardless of the precise strategy used for reconstruction, restoration, or repair of the tissue/organ of interest, cells, and biomaterials (i.e., scaffolds) provide the basic constituents needed for developing new tissue.

  • For instance, if sufficient tissue/organ viability remains in vivo, then either cells alone (i.e., cell therapy) or scaffolds alone (biomaterial therapy) may be sufficient to provide the needed regenerative response. Such an approach is feasible at this point in the disease process, as it may still be possible to leverage existing endogenous mechanisms for relatively complete tissue repair and/or restoration of organ function.

End-user Insights

The pharmaceutical & biotechnology companies segment dominated in the microcarriers market in 2023. To produce protein-based vaccines, the coding gene of the protein can be put into the plasmid and altered into the host cell (e.g., E. coli or mammalian cells), which can then express that gene into protein. The protein manufactured is then harvested, purified, and formulated into a vaccine. The manufacturing of this type of vaccine is corresponding more complex as it requires extra operation, but it can produce a high level of antigen titer. These firms provide the required environment for mass production.

The academic & research institutes segment is observed to be the fastest growing in the microcarriers market during the forecast period.

Microcarriers Market Share, By End-user, 2023 (%)

Employing bioreactors to culture cells to manufacture antigens, antibodies, and other products is the core technology underpinning the large-scale production of biological products. The combination of fine process control in biotechnology and the screening and domestication of high-expression cell lines can enhance production efficiency and product quality. Based on laboratory-scale experiments, we can optimize some conventional physical and chemical parameters and obtain a perfect training program on a larger scale in advance, which saves time during subsequent industrialization. Laboratory-scale experiments can provide pilot-scale conditions for the latest biological products, especially in the research and development of new vaccines, to maximize the yield and quality.

Microcarriers Companies

Microcarriers Market Companies

  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • Danaher Corporation
  • Bio-Rad Laboratories, Inc.
  • HiMedia Laboratories Pvt. Ltd.
  • denovoMATRIX GmbH
  • Sartorius AG
  • Corning Incorporated
  • Eppendorf SE

Microcarriers Market Recent Developments

  • In December 2023, CellRev, the bioprocessing firm revolutionizing continuous mammalian cell manufacturing, declared its proprietary media additive AggreGuard to shut out the aggregation of microcarrier-supported cells in adherent cell culture.
  • In November 2023, Teijin Frontier declared that it had enlarged new nonwoven microcarriers that enable speedy, high-quality, large-scale cell culture. This scaffolding material for a broad range of cell types facilitates adherence and growth in three dimensions.

Segments covered in the report

By Consumables

  • Media & Reagents
  • Microcarrier Beads
    • Collagen Coated Beads
    • Cationic Beads
    • Protein Coated Beads
    • Untreated Beads
    • Others

By Application

  • Biopharmaceutical Production
    • Vaccine Production
    • Therapeutic Production
  • Regenerative Medicine

By End-user

  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations & Contract Manufacturing Organizations
  • Academic & Research Institutes

By Geography

  • North America
  • Asia Pacific
  • Europe
  • Latin America
  • Middle East & Africa

Frequently Asked Questions

The global microcarriers market size is expected to increase USD 4.63 billion by 2033 from USD 1.54 billion in 2023.

The microcarriers market is anticipated to grow at a CAGR of over 11.63% between 2024 and 2033

The major players operating in the microcarriers market are Thermo Fisher Scientific, Inc., Merck KGaA, Danaher Corporation, Bio-Rad Laboratories, Inc., HiMedia Laboratories Pvt. Ltd. denovoMATRIX GmbH, Sartorius AG, Corning Incorporated, Eppendorf SE, and Others.

The driving factors of the microcarriers market are thehigh demand of cell-based vaccines & therapeutics and increasing use of 3D cell culture methods.

North America region will lead the global microcarriers market during the forecast period 2024 to 2033.

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