mRNA Synthesis and Manufacturing Market Revenue to Attain USD 5.64 Bn by 2035
Published: 27 Feb 2026
Author: Precedence Research
MRNA Synthesis and Manufacturing Market Revenue and Trends 2026 to 2035
The global mRNA synthesis and manufacturing market revenue was valued at USD 3.19 billion in 2025 and is expected to attain around USD 5.64 billion by 2035, growing at a CAGR of 5.85% during forecast period.The market is rapidly growing due to the huge demand for mRNA-based vaccines, increasing therapeutic applications in oncology and rare diseases, and the need for scalable and cell-free production.
What are the Major Factors Driving the mRNA Synthesis and Manufacturing Market?
The market is growing significantly due to key factors such as the expansion of mRNA applications beyond vaccines, technological advancements in vaccine production, advanced drug delivery systems like lipid nanoparticles that have resolved challenges regarding stability and delivery, and increased partnerships with CDMOs. Additionally, the increasing demand for tailored and targeted drug treatments for critical diseases like cancer and other genetic disorders is fueling rapid investment in mRNA manufacturing, backed by public and private funding.
Segment Insights
- By Product Type, The drug substance (APIs) segment held the largest market share of nearly 60% in 2025, primarily due to the critical role that active pharmaceutical ingredients play in delivering the intended therapeutic effect.
- By Service Type, The GMP-grade manufacturing segment held the largest market share of nearly 46% in 2025 due to stringent regulatory requirements governing the safety, quality, and consistency of clinical and commercial drug production. Good Manufacturing Practice (GMP) compliance is mandatory for products intended for human use, particularly for large-scale manufacturing aimed at global regulatory approvals.
- By Application, The vaccine production segment held the largest market share of nearly 67% in 2025 due to the increasing global emphasis on preventive healthcare and infectious disease control. Governments and health organizations are prioritizing large-scale immunization programs to reduce the spread of highly transmissible diseases and minimize overall disease burden.
- By Scale of Operation, The commercial scale segment held the largest market share of nearly 85% in 2025 due to the rapid adoption of mRNA diagnostics and therapeutics for clinical applications.
- By End User, The pharmaceutical and biotech companies segment held the largest market share of nearly 51% in 2025 due to the increasing research and development expenditures.
Regional Insights
North America registered dominance in the mRNA synthesis and manufacturing market, holding the largest share of nearly 42.4% in 2025. This is due to a combination of factors like massive investment backed by strong public and private funding, active presence of major industry players, and increasing adoption of technologies like AI in manufacturing for high-volume clinical trials.
Asia Pacific is projected to grow at the fastest CAGR of nearly 7.8% during the foreseeable period due to the rising production of vaccines and substantial investment in the biotech industry to explore cost-effective manufacturing capabilities. The region is a highly attractive option for CDMOs' activities due to the availability of a skilled workforce with cost efficiency.
mRNA Synthesis and Manufacturing Market Coverage
| Report Attribute | Key Statistics |
| Market Revenue in 2025 | USD 3.19 Billion |
| Market Revenue by 2035 | USD 5.64 Billion |
| CAGR from 2026 to 2035 | 5.85% |
| Quantitative Units | Revenue in USD million/billion, Volume in units |
| Largest Market | North America |
| Base Year | 2025 |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa |
Recent Development
- In January 2026, Innorna, a biotech company headquartered in Hong Kong, launched a game-changing drug delivery technology with a lipid nanoparticle platform, which is considered an advancement in next-generation mRNA therapies and vaccines.(Source: https://www.scmp.com)
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