Calcium Gluconate Market (By Grade: Pharmaceutical Grade, Food Grade; By Form: Liquid, Tablet, Powder, Gel; By Function: Calcium Supplement, Bone Health, Antacid, Skincare And Cosmetics; By Application: Pharmaceuticals, Food & Beverages, Nutraceuticals, Others) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2024-2033


The global calcium gluconate market size was valued at USD 98.72 billion in 2023 and is anticipated to reach around USD 179.31 billion by 2033, growing at a CAGR of 6.15% from 2024 to 2033. Rising demand for calcium gluconate from various industries, such as F&B, pharmaceutical, and agriculture, is a key factor driving market revenue growth.

Calcium Gluconate Market Size 2024 to 2033

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Calcium Gluconate Market Key Takeaways

  • The North America calcium gluconate market size was exhibited at USD 37.51 billion in 2023 and is expected to gain around USD 69.03 billion by 2033.
  • North America dominated the market with the largest market share of 38% in 2023.
  • Asia Pacific is witnessing rapid growth in the global market.
  • By grade, the pharmaceutical grade segment has captured more than 64% of market share in 2023.
  • By grade, the food grade segment is expected to grow the fastest over the projected period.
  • By form, the powder segment has accounted more than 43% of market share in 2023.
  • By form, the liquid segment is the fastest-growing segment during the forecast period.
  • By function, the calcium supplement segment held the largest market share in 2023.
  • By application, the food & beverages manufacturers segment dominated the market in 2023 and is expected to grow significantly till 2033.

Calcium Gluconate Market Size in U.S. 2024 to 2033

The U.S. calcium gluconate market size surpassed USD 28.14 billion in 2023 and is expected to be worth around USD 51.78 billion by 2033 at a CAGR of 6.28% from 2024 to 2033.

U.S. Calcium Gluconate Market Size 2024 to 2033

North America dominated the global calcium glucose market in 2023. This is because calcium gluconate is widely used in pharmaceuticals to treat calcium deficiency, osteoporosis, and other bone-related conditions, driving high demand in the region. Additionally, the availability of various calcium supplements and increasing consumer awareness about health contribute to market growth. With rising disposable income and growing health awareness, the North American market is projected to see the fastest revenue growth during the forecast period.

  • In January 2024, Healthy Extracts Inc., a platform for acquiring, developing, patenting, marketing, and distributing plant-based nutraceuticals that target select high-growth categories within the multibillion-dollar nutraceuticals market, launched LONGEVITY Anti-Aging™, a new proprietary formulation designed to support skin vitality, arterial flexibility, and cellular and joint health.

Asia Pacific is witnessing rapid growth in the calcium gluconate market, driven by increasing consumer demand for healthy products. A significant portion of the population in this region suffers from calcium deficiency, which leads to a greater emphasis on health consciousness and the use of food additives and supplements to address calcium needs.

Calcium Gluconate Market Share, By Region, 2023 (%)

Countries like China, India, and Japan play key roles in driving industry growth. Despite being the largest milk producer, India faces a notable shortage in calcium intake. This has led to a growing trend of consuming calcium supplements, which has boosted the growth of the calcium gluconate market in the region.

  • In July 2023, Oriflame India, the holistic beauty and wellbeing company, launched two new health supplements as part of its Wellosophy range. The Iron Complex, designed specifically for women, and the Calcium fortified with Vitamin D and Magnesium supplements provide an extra boost to support busy routines and maintain an active and healthy lifestyle.

Calcium Gluconate Market Size in Europe 2023 to 2033

The Europe calcium gluconate market size was calculated at USD 26.65 billion in 2023 and is projected to expand around USD 49.31 billion by 2033, poised to grow at a CAGR of 6.28% from 2024 to 2033.

Year Market Size (USD Billion)
2023 26.65
2024 28.82
2025 30.15
2026 32.06
2027 26.65
2028 36.26
2029 38.56
2030 41.00
2031 43.60
2032 46.37
2033 49.31


Calcium Gluconate Market Overview

Calcium gluconate is a type of calcium salt derived from gluconic acid. It serves as a calcium supplement and is also used as a key ingredient in pharmaceuticals. You can find it in various forms like powder, liquid, and tablets. This mineral supplement is produced by extracting glycolic acid from lime or calcium carbonate. It's considered unique among essential medicines. Doctors often prescribe calcium gluconate to treat conditions that lead to calcium deficiency, such as hyperparathyroidism-related hypocalcaemia, hypocalcaemia tetany, or deficiency due to rapid growth or pregnancy.

Calcium gluconate, due to its potent nature, restricts its use in many food products, even those fortified with nutrients. In the food industry, calcium gluconate acts as a firming agent in jellies, jams, and fruit preserves, which enhance the texture and stability. It's also added as a nutrient supplement in dairy products, breakfast cereals, and infant formulas. You'll also find it in beverages like bottled water, cold drinks, and juices, as well as in various confectionery items, baked goods, and soy products.

Calcium Gluconate Market Growth Factors

  • Rising health awareness among most of the population is one of the key factors driving the growth of the calcium gluconate market.
  • The growing geriatric population, which is more susceptible to calcium deficiencies, is expected to fuel the growth of the calcium gluconate market over the forecast period.
  • Increasing incidence of osteoporosis is also anticipated to boost the calcium gluconate market growth further.
  • The rising need for sustainable agricultural solutions can help in the expansion of the calcium gluconate market in the future.
  • Growing demand from end-use productions like foodstuff & drinks is propelling the calcium gluconate market growth.

Calcium Gluconate Market Scope

Report Coverage Details
Growth Rate from 2024 to 2033 CAGR of 6.15%
Global Market Size in 2023 USD 98.72 Billion
Global Market Size in 2024 USD 104.79 Billion
Global Market Size by 2033 USD 179.31 Billion
Largest Market North America
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered By Grade, By Form, By Function, and By Application
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa


Calcium Gluconate Market Dynamics

Driver: Rising incidence of calcium deficiency

The increasing prevalence of calcium deficiency worldwide is a major factor driving the growth of the calcium gluconate market. It's estimated that over 3.5 million people worldwide are at risk of calcium deficiency. Hypocalcaemia, or low calcium levels, can lead to various medical issues, ranging from mild symptoms to potentially severe or chronic conditions. These factors will significantly contribute to the market share of calcium gluconate. Additionally, the demand for calcium gluconate is also being fueled by the nutraceutical industry. Calcium gluconate serves as a key ingredient in the production of various calcium-based health supplements.

  • In September 2023, meal received the Food and Drug Administration’s permission for calcium gluconate in sodium chloride injection, 1000 mg/50 ml and 2000 mg/100 ml. The product received the FDA’s Competitive Generic Therapy designation with 180-day exclusivity, and it is currently on the FDA shortage product list, Amneal noted.

Restraint: Side effects

Excessive intake of calcium gluconate can lead to unpleasant side effects like constipation, decreased appetite, dry mouth, nausea, and vomiting. These effects pose a challenge to the growth of the calcium gluconate market. Also, strict regulations from food authorities limit its usage in food products, which can restrain market growth. Furthermore, the availability of alternative calcium supplements and limited consumer awareness about the benefits of calcium gluconate hinder its market penetration. Consumers may also be cautious due to potential safety concerns related to high-dose calcium supplementation.

Opportunity: Research and development

Research and development efforts are underway to discover new ways to formulate and deliver calcium gluconate, creating the way for innovation. Venturing into emerging markets with improving healthcare infrastructure and higher healthcare spending presents growth opportunities. There's also a focus on developing calcium gluconate supplements with improved bioavailability for better absorption, which greatly benefits the growth of the calcium gluconate market.

Collaboration among healthcare professionals and institutions can help promote the benefits of the calcium gluconate market. Establishing strategic partnerships with pharmaceutical companies to integrate calcium gluconate into their existing product lines is also a key factor in expansion. Investment in marketing campaigns and educational initiatives will raise awareness about calcium gluconate and its various uses. Furthermore, the cosmetic industry shows a rising demand for calcium gluconate, particularly for formulating skincare and haircare products.

  • In April 2022, Fresenius Kabi announced it had introduced two new presentations of Calcium Gluconate in Sodium Chloride Injection in the United States in the company’s proprietary, ready-to-administer freeflex® containers.

Grade Insights

The pharmaceutical-grade segment dominated the calcium gluconate market in 2023. Pharmaceutical-grade calcium gluconate is utilized to treat medical conditions such as hyperkalemia, hypercalcemia, etc. Moreover, pharma-grade calcium gluconate is known for its superior purity and high quality. It also has excellent bioavailability and is hence widely used in various medical applications.

Calcium Gluconate Market Share, By Grade, 2023 (%)

The food grade segment is expected to grow the fastest over the projected period. This is attributed to the rising demand for food-grade calcium gluconate products and services, which is a major driver for the growth of the calcium gluconate market. Factors like population growth, urbanization, and evolving consumer preferences can contribute to this demand. Continuous technological innovations also play a key role in improving the efficiency and effectiveness of these products and services.

Form Insights

The powder segment dominated the calcium gluconate market. Powdered calcium gluconate is easily used in different foods and cool drinks to improve and fortify its nutritional calcium content.

  • In December 2022, China dairy firm Junlebao launched a new milk powder targeted at supporting calcium absorption in middle and old-aged consumers and hopes to rejuvenate the well-established category by improving bio-accessibility and bioavailability.

Calcium Gluconate Market Share, By Form, 2023 (%)

The liquid is the fastest-growing segment during the forecast period. The ease of use and quick absorption of liquid calcium gluconate make it a preferred choice, especially in emergency medical situations where calcium needs to be administered promptly. Its ability to dissolve easily and be flexible in its application allows it to be used in various industries, including food and beverage, pharmaceuticals, and agriculture.

Function Insights

The calcium supplement segment held the largest share of the calcium gluconate market in 2023 and is also anticipated to grow at the fastest rate during the studied period. Calcium gluconate is widely utilized as a calcium supplement to combat calcium deficiencies and promote bone health. This makes it a sought-after choice, particularly among individuals such as pregnant women, the elderly, and those with specific medical conditions who require daily calcium supplementation. Moreover, the market for calcium gluconate tablets is expected to grow in the coming years due to increasing demand for nutraceuticals and dietary supplements.

  • In July 2023, Oriflame India, a holistic beauty and wellbeing company, launched two new health supplements under its Wellosophy range – Iron Complex, developed especially for women, and Calcium fortified with Vitamin D and Magnesium.

Application Insights

The food & beverages manufacturers segment dominated the calcium glucose market share in 2023 and is expected to grow significantly till 2033. This is because calcium gluconate is commonly added to food and drinks as a mineral supplement and ingredient. It acts as a preservative for various food items like baked goods, dairy products, and canned fruits and vegetables. The increasing awareness of calcium deficiency and the health benefits of consuming calcium-fortified products are driving the demand for calcium gluconate in the food and beverage industry.

Calcium Gluconate Market Recent Developments

  • In May 2023, Kemira, a Finnish company that provides chemicals and services for the water, energy, and industrial markets, announced that it had acquired the calcium propionate business of Eastman Chemical Company. The acquisition is expected to strengthen Kemira's position in the global calcium propionate market.
  • In April 2023, Perstorp Chemicals Pvt. Ltd., an Indian manufacturer of specialty chemicals, announced that it had increased its production capacity for calcium propionate. The increase in capacity is expected to meet the growing demand for calcium propionate in India.
  • In March 2023, Macco Organiques Inc., a Czech Republic-based manufacturer of food additives, announced that it had received approval from the US Food and Drug Administration (FDA) for its calcium product. The approval allows the company to sell its calcium propionate product in the United States.

Calcium Gluconate Market Companies

  • Pfizer
  • Novartis
  • Amphastar
  • Akorn
  • West-Ward Pharmaceuticals
  • Fresenius Kabi USA
  • Merck
  • Mylan Institutional LLC
  • Grifols USA LLC
  • Baxter International

Segments Covered in the Report

By Grade

  • Pharmaceutical Grade
  • Food Grade

By Form

  • Liquid
  • Tablet
  • Powder
  • Gel

By Function

  • Calcium Supplement
  • Bone Health
  • Antacid
  • Skincare and Cosmetics

By Application

  • Pharmaceuticals
  • Food & Beverages
  • Nutraceuticals
  • Others

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Frequently Asked Questions

How big is the calcium gluconate industry?
The global calcium gluconate market size is expected to increase USD 179.31 billion by 2033 from USD 98.72 billion in 2023.
What is the growth rate of the calcium gluconate industry?
The global calcium gluconate market will register growth rate of 6.15% between 2024 and 2033.
Who are the prominent players operating in the calcium gluconate market?
The major players operating in the calcium gluconate market are Pfizer, Novartis, Amphastar, Akorn, West-Ward Pharmaceuticals, Fresenius Kabi USA, Merck, Mylan Institutional LLC, Grifols USA LLC, Baxter International, and Others.
Which are the driving factors of the calcium gluconate market?
The driving factors of the calcium gluconate market are an increasing prevalence of calcium deficiency worldwide and rising need for sustainable agricultural solutions.
Which region will lead the global calcium gluconate market?
North America region will lead the global calcium gluconate market during the forecast period 2024 to 2033.

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