Gene Synthesis Market (By Method: Solid-phase synthesis, Chip- based synthesis, PCR- based Enzyme synthesis; By Service: Antibody DNA synthesis, Viral DNA synthesis, Others; By Application: Gene & cell therapy development, Vaccine development, Diseases diagnosis, Others; By End Users: Biotechnology & pharmaceutical companies, Academic & government research institutes, Contract research organizations) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2023-2032


The global gene synthesis market size was exhibited at USD 2.10 billion in 2022 and is expected to surpass around USD 17.99 billion by 2032 with an enhanced CAGR of 23.97% during the forecast period 2023 to 2032.

Gene Synthesis Market Size 2023 To 2032

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Key Takeaways

  • North America accounted highest revenue share of 39% in 2022.
  • By method, the solid-phase synthesis segment has accounted revenue share of 37% in 2022.
  • By service, the antibody DNA synthesis segment has captured 61% revenue share in 2022. 
  • By application, the gene & cell therapy development segment has generated 36% revenue share in 2022.
  • By end use, the academic and government research institutes segment accounting revenue share of 56% in 2022. 

Gene synthesis involves the formation of genes with the chemical process led to the formation of genes with synthetic biology with construction of genes with the nucleotide. In living organic, for synthesis of genes DNA is must but in artificial gene synthesis DNA is not required it is chemically synthesized in the labs by the professional experts with the huge experience individual. In synthesis of genes, it involves two stages such as DNA printing produced by solid phase DNA synthesis and production of oligonucleotide below 200 base pairs. Second stage includes interaction of oligonucleotides with the DNA base pairs.

Genes are mostly the major factor for production of the DNA sequence and increased protein functioning. Gene synthesis artificially to be produced by solid phase synthesis utilised for molecular cloning, protein fusion. Synthesis of genes with traditional cloning techniques with reduced time for synthesis, reduced cost for synthesis. Biology is developed with the artificially developed genes with the help of chemical synthesis which helps to expand the market of gene synthesis with increased rate. Increased government support for synthesis of gene biologically which is utilized in chronic disorders for faster relief with increased funding from the government with increased reimbursement policies imposed by the company for the benefit of the people with increased market size of gene synthesis during the forecast period.

Impact of COVID-19 on the gene synthesis with the increased market growth of the gene synthesis market. Increased utilization of gene synthesis in the research and development with increased manufacturing and production of products with the higher efficacy with increased number of vaccines helps to drive the market of gene synthesis during the forecast period.

Growth Factors

The advanced developed technologies in gene synthesis with biological synthetic process widely accepted technology in the market in the DNA developed technology with producing proteins and increased function helps to drive the market of gene synthesis. Increased research and technology for new synthesis and utilization of genes for new development with enhanced innovation and long-term therapy production such as targeted therapy, immunotherapy with increasing chronic disorders among the population majorly oncological disorder to be the highest with enhanced rising number of cases and increased for the new innovative therapies. Which helps to accelerate the market of gene synthesis during the forecast period.

Gene synthesis to be the one with new innovation development and enhanced demands for the gene synthesis widely utilised in the medical sector by the professionals. Life sciences market in the science sector urge the market growth with new developments in the market with increased diagnostic products utilised for diagnosis of disorder. Increased research and development by the key market players in the gene synthesis with introducing new biologically synthesized genes with enhanced investment from the companies for new technology with new variations and enhanced efficiency of the genes in chronic disorder and increased growth of the pharmaceutical industries. 

Increased government support with enhance funding in development of the genes and increased policies of reimbursement so that common people can take the benefit of the newly developed therapy helps to accelerate the market of gene synthesis with increasing demands. 

Gene Synthesis Market Scope

Report Coverage Details
Market Size in 2023

USD 2.50 Billion

Market Size by 2032

USD 17.99 Billion

Growth Rate from 2023 to 2032 CAGR of 23.97%
Base Year 2022
Forecast Period 2023 to 2032
Segments Covered Method, Service, Application, End Users, and Geography
Companies Mentioned OriGene Technologies,Inc, Integrated DNA Technologies, Inc, Thermo Fisher Scientific, Inc, ProMab Biotechnologies, Inc, Eurofins Scientific, Biomatik, ProteoGenix, Bosyer Biological Technology, GenScript, Brooks Automation, Inc (GENEWIZ), Twist Bioscience, Codex DNA

 

Gene Synthesis Market Dynamics

Key Market Drivers

Increased prevalence of chronic disorders

  • Rapid expansion of the disorders among the population with changing lifestyle of the people. Increased number of chronic disorders such as oncology, cardiovascular, HIV, gastrointestinal disorders and many more help to expand the market of gene synthesis.  Utilization of the gene synthesis in curing the chronic disorders with increased research and development with advance technologies developed in gene synthesis produced biologically with developed innovations and enhance efficacy and safety of the produced genes with improved demands from the medical sector with increased techniques and skill work required for carrying out the procedures. Increased gene synthesis with significant application of genes in producing the new vaccines with increased funding from the companies to enhance the market growth during the forecast period.

Enhance adaption of the gene therapy

  • Gene therapy developed with advance technologies and new innovative therapies developed for prevention of the various disorders developed in the rising population help to drive the market of gene synthesis. In gene therapy it includes insertion of the genes in patients’ cells and increased efficiency of the gene to cure the disease with long term therapy involved with increased benefits of the treatment. Increased demands from the medical sector with increased quality life of the individuals with improved technologies in treating the disorder help to grow the market of gene synthesis.

Key Market Challenges 

  • High cost of the treatment for the chronic disorder - Developing new advance innovative technologies in the gene therapy with improved efficacy of the treatment. Which led to increased cost of the treatment and the therapies involved for prevention of the disorder. Increased development in various regions with increased cost may hamper the market of gene synthesis during the forecast period.
  • Lack of skill - The rapid advancement of the technologies involved in gene therapy with increased skill work and experienced individual is required for the insertion of the genes or to carry out procedure of gene therapy in patients. Lack of skill among the individual to carry out the therapy may decline the market of gene synthesis during the forecast period.
  • Availability of the options - Increase number of option available to treat the chronic disorders rising in day-to-day life with developed lifestyle has led to increasing diseases among the people and developed treatments and new innovative technologies for prevention of the disorder help to boost the market of gene synthesis during the forecast period.

Key Market Opportunities

  • Increasing disorder - Increasing number of chronic disorders among the people with developed diseases such as cancer, HIV, cardiovascular, AIDS, tuberculosis, respiratory disorders and many more diseases with increased demand for the developed technologies and innovative treatments such as gene therapy involved for prevention of the disorder and increased research and technology helps to accelerate the growth of gene synthesis during the forecast period.
  • Government support -   Enhance government support for the synthesis of new genes with increased efficiency of the therapy with increased research and development with enhance investment from the government for new developments and increased government policies of reimbursement so that every individual can take benefit of the treatment of new technologies developed. Which helps to propel the growth of gene synthesis in the market.

Method Insights

Gene synthesis segmentation on the basis of the method involves solid-phase synthesis with the largest market revenue share with increased synthesis of the genes. Which owe to high market share in the year 2022 with the growth of 37% increased rate. Enhance accuracy of the solid phase synthesis with the increased research and development with enhance cost of the synthesis involves can hamper the market of the gene synthesis. Increased efficiency of the gene therapy with increased demands from the market led to boost the market of gene synthesis during the forecast period.

Services Insights

Gene synthesis on the basis of services, antibody DNA synthesis to hold the highest market with increased revenue share of the gene synthesis, Increased cloning and synthesis of the genes with the chemical process.

Gene Synthesis Market Share, By Service, 2021 (%)

Viral gene to be the highest market share with increasing research and development in virus related. Structural and non-structural protein genes are synthesized. Which accelerated the growth of gene synthesis with enhanced market value.

Application Insights

Gene synthesis on the basis of application, Gene and cell therapy to enhance the market value with the largest market growth in gene synthesis with enhanced demands from the medical sectors with an increasing prevalence of the chronic disorders and increased gene therapy involved in treating the disorders with developed efficiency of the therapy with improved effect of the therapy and faster recovery rate.  Academic institutes and company also to grow the market of gene synthesis across the regions with increased utilization of the gene therapy help to boost the market of gene synthesis during the forecast period.

End-Users Insights

Gene synthesis on the basis of end user, Academic and government research institute with enhance market growth of gene synthesis. Which led to increased research and development and enhance utilization with increased funding from the government for increasing the development in the chronic sector with improved gene therapy with new innovations. The biotechnology and pharmaceutical companies with an increased the market value of gene synthesis with enhance utilization of biotechnology in gene synthesis. Which accelerates the market of gene synthesis with increased market value.

Gene Synthesis Market Share, By Region, 2022 (%)

Regions Revenuie Share in 2022 (%)
North America 39%
Asia Pacific 22%
Europe 27%
Latin America 7%
MEA 5%


Regional Insights

Gene synthesis on the basis of geography, North America to be largest region in the market with increased market size of the gene synthesis with increased research and development with new innovations developed with the genes increased gene therapy with increasing chronic disorders help to boost the market of gene synthesis. Asia Pacific region to be second highest market with increasing demands from the health sector with increased number of gene therapies helping to boost the market of gene synthesis. Other regions Europe, Latin America, Middle East and Africa also help to grow the market of gene synthesis.

Recent Developments

  • In the year 2022 July, OraSure Technologies introduced the OmniGene which is the Gut DNA and DNA product (OMR-205).
  • In the year 2022 April, For the syntax system customer developed the DNA script introduced in an early program with the latest advanced technologies developed in DNA synthesis technique.

Market Segmentation

By Method

  • Solid-phase synthesis
  • Chip-based synthesis
  • PCR- based Enzyme synthesis

By Service

  • Antibody DNA synthesis
  • Viral DNA synthesis
  • Others

By Application

  • Gene & cell therapy development
  • Vaccine development
  • Diseases diagnosis
  • Others

By End Users

  • Biotechnology & pharmaceutical companies
  • Academic & government research institutes
  • Contract research organizations

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East & Africa (MEA)

Frequently Asked Questions

What is the current size of gene synthesis market?
The global gene synthesis market size was accounted at USD 2.10 billion in 2022 and it is expected to reach around USD 17.99 billion by 2032.
What will be the CAGR of global gene synthesis market?
The global gene synthesis market is poised to grow at a CAGR of 23.97% from 2023 to 2032.
Who are the prominent players operating in the gene synthesis market?
The major players operating in the gene synthesis market are OriGene Technologies,Inc, Integrated DNA Technologies, Inc, Thermo Fisher Scientific, Inc, ProMab Biotechnologies, Inc, Eurofins Scientific, Biomatik, ProteoGenix, Bosyer Biological Technology, GenScript, Brooks Automation, Inc (GENEWIZ), Twist Bioscience, Codex DNA
Which are the driving factors of the gene synthesis market?
Increasing emphasis on clinical research, increasing usage in the development of personalized medicine, supportive government policies and increased prevalence of chronic disorders these are driving the growth of the gene synthesis market.
Which region will lead the global gene synthesis market?
North America region will lead the global gene synthesis market during the forecast period 2023 to 2032.

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