Antibody Purification Service Market Size, Share and Trends 2026 to 2035
Antibody Purification Service Market (By Service Type: Protein A/G Chromatography, Ion Exchange Chromatography, Hydrophobic Interaction, Size Exclusion, Mixed Mode; By Application: Monoclonal Antibodies, Antibody Drug Conjugates, Polyclonal Antibodies, Antibody Fragments; By End Use: Pharmaceutical Companies, Biotechnology Companies, Contract Research Organizations, Academic Research Institutions) - Global Industry Analysis, Size, Trends, Leading Companies, Regional Outlook, and Forecast 2026 to 2035
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What is the Antibody Purification Service Market Size in 2026?
The global antibody purification service market size was calculated at USD 3.01 billion in 2025 and is predicted to increase from USD 3.31 billion in 2026 to approximately USD 7.74 billion by 2035, expanding at a CAGR of 9.90% from 2026 to 2035.The antibody purification service market is expected to grow due to the increasing demand for therapeutic antibodies, biosimilars, and personalized medicines. Advancements in affinity chromatography are another major factor for the growth of the market. Developed services of CMOs and CROs to enhance the research and application procedure, which also helps to fuel the growth of the market.
Key Takeaways
- North America led the global antibody purification service market in 2025 with approximately 42.3% share.
- Asia Pacific is observed to be the fastest-growing region in the foreseen period with the highest CAGR of 10.1%.
- By service type, the protein A/G chromatography segment led the global market in 2025 with approximately 45% share.
- By service type, the ion exchange chromatography segment is observed to be the fastest-growing with a CAGR of 8.5% in the forecast period.
- By application, the monoclonal antibodies segment led the global industry with approximately 68% share in 2025.
- By application, the antibody-drug conjugates segment is observed to be the fastest-growing segment with a CAGR of 8.6% in the forecast period.
- By end use, the pharmaceutical companies segment led the global market with approximately 52% share in 2025.
- By end use, the biotechnology companies segment is observed to be the fastest-growing segment in the foreseen period, with the highest CAGR of 8.9%.
What is the Antibody Purification Service Market?
The antibody purification service market consists of services provided by contract research organizations (CROs), contract manufacturing organizations (CMOs), and biotechnology firms. The main role of such firms is to isolate the antibodies from various sources and purify them, which is further helpful for the growth of the market. Such antibodies can be derived from various sources, such as serum, ascites fluid, or hybridoma cell culture supernatants, for the purification process. The market allows the pharmaceutical and biotechnology companies to outsource such complex purifying procedures requiring high capital, and specialized downstream processing helpful to achieve high-purity, high-activity antibodies, for research, diagnostic, and therapeutic applications.
Role of Technology in the Growth of the Antibody Purification Service Market
Technological advancements have a major role in the growth of the market. It helps to enhance efficiency, scalability, and purity, further propelling the growth of the market. Advancements in chromatography techniques, non-chromatographic methods like filtration and precipitation, enable high-throughput production for therapeutic, diagnostic, and research applications, along with lowering costs, further fueling the growth of the market.
High-performance liquid chromatography and affinity chromatography are some of the essential and technologically advanced purification methods, further fueling the growth of the market. Non-chromatographic techniques in the form of precipitation, flocculation, and filtration are highly demanding lately as they ensure consistent product quality and maintain cost-efficiency, which is helpful to fuel the growth of the market.
Antibody Purification Service Market Trends
- Dominance of Monoclonal Antibodies: Higher therapeutic success and increased R&D for chronic diseases such as cancer or any cardiovascular issue are one of the major factors fueling the growth of the market.
- Outsourcing the Purification Process: Biopharmaceutical companies outsourcing the antibody purification process to CDMOs for their expertise in the field and helpful in high-quality purification helps to fuel the growth of the market.
- Use of Disposable Medical Equipment: Higher demand for infection control and lower the chances of cross-contamination, along with lowering the capital costs, leading to higher demand for single-use bioreactors and purification systems, also helps to fuel the growth of the market.
- Technological Advancements: Higher demand for technologically advanced purification methods for higher purity, stability, and speed in protein purification to meet regulatory standards of therapeutic antibodies is another major factor propelling the growth of the body.
Market Scope
| Report Coverage | Details |
| Market Size in 2025 | USD 3.01Billion |
| Market Size in 2026 | USD 3.31 Billion |
| Market Size by 2035 | USD 7.74 Billion |
| Market Growth Rate from 2026 to 2035 | CAGR of 9.90% |
| Dominating Region | North America |
| Fastest Growing Region | Asia Pacific |
| Base Year | 2025 |
| Forecast Period | 2026 to 2035 |
| Segments Covered | Service Type, Application,End Use, and Region |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa |
Segmental Insights
Service Type Insights
Which Component of the Service Segment led the Global Market in 2025?
The protein A/G chromatography segment dominated the global antibody purification service market in 2025 with approximately 45% share. The segment also focuses on outsourcing the purification procedure for drug development, research, and manufacturing. Growing demand for monoclonal antibodies, rising prevalence of chronic diseases, along with the growth of biologics, are also some of the vital factors. A set of various other factors, such as high-capacity, cost-effective resins, and high-throughput chromatography, is also one of the major factors fueling the growth of the market.
The ion exchange chromatography segment is expected to be the fastest-growing segment with a CAGR of 8.5% in the antibody purification service market in the foreseeable period. It is a versatile and cost-effective method of antibody purification, helpful for the growth of the market. The segment also observes growth due to its major properties, such as high-throughput suitability in separating therapeutic proteins and monoclonal antibodies from contaminants. The segment majorly focuses on its 3-step purification to remove impurities such as HCPs, DNA, and virus particles. Technological advancements in the form of advanced ion-exchange membrane chromatography, useful for high-efficiency separation, also help to fuel the growth of the segment in the foreseeable period.
Application Insights
Why did the Monoclonal Antibodies Segment lead the Global Market in 2025?
The monoclonal antibodies segment led the market in 2025 with approximately 68% share due to higher demand in therapeutic, diagnostic, and research applications, fueling the growth of the market. The rising prevalence of chronic disorders such as cancer, cardiovascular problems, and autoimmune diseases, leading to higher demand for their easy and effective treatment options, is another major factor for the growth of the segment. The other major factors are expanding pharmaceutical R&D, increasing FDA approvals for new-antibody-based drugs, and the need for specialized, rapid, and efficient downstream processing.
The antibody-drug conjugates segment is expected to grow at the fastest CAGR of 8.6% in the forecast period. The segment observes growth due to high-demanding factors such as HER2-targeted therapies and payloads like MMAE. Higher demand for efficient cancer treatment options, robust pipeline, and increased FDA approvals, also help to fuel the growth of the segment. The segment also involves ensuring the structural integrity of the antibody, maintaining the stability of the linker, and achieving high purity for therapeutic safety.
End Use Insights
Why did the Pharmaceutical Companies Segment Lead the Global Market in 2025?
The pharmaceutical companies segment led the global antibody purification service market in 2025 with approximately 52% share. The market also observes growth due to the growing prevalence of chronic disorders such as cancer and autoimmune diseases. Higher demand for intensive R&D in therapeutic antibodies to treat chronic diseases also helps to fuel the growth of the market. Outsourcing of antibody purification by pharmaceutical companies to CDMOs and CROs for improved focus on major drug therapy also helps to fuel the growth of the market. Higher demand for next-generation formats such as bispecific antibodies, antibody-drug conjugates, and trispecific antibodies, requiring specialized purification methods such as multi-modal chromatography, is helpful for the segment's growth.
The biotechnology companies segment is estimated to be the fastest-growing, with a CAGR of 8.9% in the antibody purification service market in the forecast period, due to higher demand for high-quality, customized, and monoclonal antibodies for therapeutic, diagnostic, and research applications. Higher investments in R&D of the industry in biologics and higher demand for outsourcing the purification procedure to lower the operational costs help to fuel the growth of the segment. The main aim of the market involves monoclonal antibody purification, which is essential for therapeutic safety and efficiency, and helps boost the growth of the market. The segment majorly focuses on technologically advanced purification methods such as antigen affinity-purification, physicochemical techniques, and class-specific methods, further propelling the growth of the segment in the foreseeable period.
Regional Insights
How Big is the North America Antibody Purification Service Market Size?
The North America antibody purification service market size is estimated at USD 1.27 billion in 2025 and is projected to reach approximately USD 3.27 billion by 2035, with a 9.92% CAGR from 2026 to 2035.
Why did North America lead the Global Market in 2025?
North America leads the global antibody purification service market with approximately 42.3% in 2025. The region approximately represents 50% of the global purification demand for clinical and commercial-grade antibodies, which helps to fuel the growth of the market. Higher demand for therapeutic monoclonal bodies also helps to fuel the growth of the market. Growing chronic disorders such as autoimmune diseases, cancer, cardiovascular issues, and other similar problems also propel the growth of the market. Higher investment in the R&D of the industry for high-quality purification methods also boosts the growth of the market. Growing outsourcing of purification services to the experts of the industry, along with higher demand for high-quality, high-purity antibodies for research, diagnostics, and therapeutics, also helps to fuel the growth of the market.
What is the Size of the U.S. Antibody Purification Service Market?
The U.S. antibody purification service market size is calculated at USD 1.02 billion in 2025 and is expected to reach nearly USD 2.64 billion in 2035, accelerating at a strong CAGR of 9.98% between 2026 and 2035.
The U.S. Antibody Purification Service Market Trends
The U.S. has a major contribution to the growth of the market due to factors such as higher demand for monoclonal antibodies, therapeutic proteins, and outsourced downstream processing. Higher demand for therapeutic antibodies, fast turnaround purification to lower development cost, and the rise of personalized medicine also help to propel the growth of the market. It helps to manage the complex purification procedure with ease and also to manage the costs as well.
Why is the Asia Pacific region expected to be the fastest-growing region in the Foreseen Period?
Asia Pacific is expected to be the fastest-growing region in the forecast period with the highest CAGR. The market in the region is observing rapid growth due to growing biopharmaceutical R&D, rising demand for therapeutic antibodies, and the expansion of CROs in the region, which will help propel the growth of the market in the foreseeable period. Higher demand for specialized and cost-effective purification methods, along with the expertise of the CROs, is another major factor fueling the growth of the market. Technologically advanced purification methods, high-throughput screening, and automation for antibody-based therapies also help to fuel the growth of the market in the foreseeable period.
China Antibody Purification Service Market Trends
China will make a major contribution to the growth of the market in the foreseeable period. The growing demand for therapeutic antibodies, government support for the R&D, and higher demand for CROs and CDMOs in the region are some of the major factors propelling the growth of the market. Factors such as the development of the biopharmaceutical infrastructure of the region, increased focus on targeted therapies to treat chronic diseases, and higher demand for specialized antibody production also help to fuel the growth of the market in the foreseeable period.
Antibody Purification Service Market Companies
- Thermo Fisher Scientific
- Merck KGaA
- GE Healthcare (Cytiva)
- Bio Rad Laboratories
- GenScript Biotech
- Abcam
- Pall Corporation
- Sartorius AG
- Agilent Technologies
- BioLegend
- Miltenyi Biotec
- Creative Biolabs
- Rockland Immunochemicals
- COVALAB
- BBI Solutions
Recent Developments
- In January 2026, Boehringer Ingelheim and Simcere Pharmaceutical Group Ltd. announced a license and collaboration agreement to develop SIM0709, a pre-clinical TL1A/IL23p19 bispecific antibody from Simcere, for the treatment of inflammatory bowel disease (IBD). (Source- https://www.globenewswire.com)
- In January 2026, Fortitude Biomedicines, Inc., announced the company's launch following the closing of a $13 million Seed financing, co-led by K2 Bio Partners, Shanghai Healthcare Angel Capital (SHAC), and Elikon Venture, with additional investment from Everjoy Fortune and Taihill Venture.(Source- https://www.businesswire.com)
Segments Covered in the Report
By Service Type
- Protein A/G Chromatography
- Ion Exchange Chromatography
- Hydrophobic Interaction
- Size Exclusion
- Mixed Mode
By Application
- Monoclonal Antibodies
- Antibody Drug Conjugates
- Polyclonal Antibodies
- Antibody Fragments
By End Use
- Pharmaceutical Companies
- Biotechnology Companies
- Contract Research Organizations
- Academic Research Institutions
By Region
- North America
- Europe
- Asia-Pacific
- Latin America
- Middle East & Africa
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