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Table Of Content
January 2025
Single-Cell Genomics Market (By Product and Service: Instruments, Consumables, Software and Bioinformatics Tools, Services; By Technology: Single-Cell RNA Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, DNA Methylation and Epigenomics, Single-Cell Multi-omics, Single-Cell Proteomics, Others; By Workflow: Sample Preparation, Isolation and Sorting, Genomic Sequencing, Data Analysis and Interpretation; By Application: Oncology, Immunology, Neurology, Stem Cell Research, Developmental Biology, Infectious Diseases, Others; By End User: Academic and Research Institutes, Pharmaceutical and Biotechnology Companies, Clinical and Translational Research Centers, Contract Research Organizations, Diagnostic Laboratories, Others;) - Global Industry Analysis, Size, Trends, Leading Companies, Regional Outlook, and Forecast 2025 to 2034
The global single-cell genomics market is witnessing rapid growth as researchers use high-resolution sequencing to analyze individual cells for disease profiling and therapeutic development. The market is driven by advancements in sequencing technologies, rising applications in precision medicine, and expanding research in complex disease biology.
The single-cell genomics market focuses on technologies and services that analyze the genetic and transcriptomic information of individual cells, providing unprecedented insights into cellular heterogeneity, disease mechanisms, and therapeutic targets. Unlike bulk sequencing methods, single-cell approaches enable precise profiling of rare cell populations, tumor microenvironments, and immune responses. Key technologies include next-generation sequencing (NGS), single-cell RNA sequencing, microfluidics, and advanced bioinformatics tools.
Applications span oncology, neurology, immunology, stem cell biology, and infectious disease research, with growing use in drug discovery and precision medicine. The market is propelled by increasing adoption of single-cell sequencing in clinical research, advances in microfluidics and droplet-based systems, and integration with AI-driven analytics. North America dominates, while the Asia Pacific shows rapid expansion.
The merging of multi-omics and spatial single-cell genomics is creating new and exciting opportunities to discover biomarkers and therapeutic targets. In May 2023, the Deepcell company launched its AI-enabled REM-I platform, designed to speed up single-cell analysis and advance a novel field called morpholomics - enabling researchers to collect rich/robust complex cellular features beyond standard genomics. (Source: https://deepcell.com)
| Report Coverage | Details |
| Dominating Region | North America |
| Fastest Growing Region | Asia Pacific |
| Base Year | 2024 |
| Forecast Period | 2025 to 2034 |
| Segments Covered | Product and Service, Technology, Workflow, Application, End User, and Region |
| Regions Covered | North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa |
What is Driving the Growth of Single-Cell Genomics?
One of the biggest recent catalysts of the single-cell genomics field has been the emergence of CRISPR-based perturbation screens with single-cell readouts, which provide scientists with the ability to interrogate gene function and disease mechanisms with unprecedented levels of granularity. In February 2025, “Perturb-seq” approach that Illumina is launching, at the end of 2025, which can handle 10,000, 100,000, and 1 million cells per sample and allow for much deeper insights into the actions of guide RNAs on the transcriptome in health and disease. (Source: https://www.illumina.com)
Another area experiencing growth is academic and trust-led databases that contain treatment responses; CellResDB contains approximately 4.7 million cells from 72 scRNA-seq datasets across 24 cancer types, including both categorized responder vs non-responder patient samples. This provides a powerful resource to investigate therapy resistance in patients at single-cell resolution. All of these innovations will increase the capacity to dissect cellular heterogeneity, track clonal evolution, and reveal the mechanisms driving drug resistance—all of which will accelerate discoveries in medicine and biotechnology. (Source: https://pmc.ncbi.nlm.nih.gov)
Are Complexity Issues in Single-Cell Genomics Data Hindering Progress?
The distinguishing complexity of single-cell data continues to be a major bottleneck. Single-cell datasets often possess high dimensionality, sparsity, and noise, introducing difficulties when it comes to their interpretation and effective analysis. For example, single-cell RNA sequencing data often show low coverage of the genome and considerable amplification bias, in addition to complicating bioinformatics analysis.
Finally, single-cell sequencing is also complicated further by the addition of multi-omics data due to complications in data structure and potential noise from biological and technical sources. The rapid growth in the amount of complex data being produced means more sophisticated computational tools and algorithms will be needed to handle and analyze this data efficiently. If left unaddressed, there may be limits to the impact that single-cell genomics will have on science in the future.
Convergence of Multi-Omics Spatial Single-Cell Genomics
An exciting opportunity exists to merge spatial single-cell genomics with the discovery of biomarkers and therapeutic targets. In July 2025, the TISHUMAP project was launched by 10x Genomics and the A*STAR Genome Institute of Singapore, applying their Xenium spatial platform and Artificial Intelligence, to investigate tumor samples and catalyze the discovery of novel targets and biomarkers.(Source: https://www.prnewswire.com)
Which Product and Service Dominates the Single-Cell Genomics Market?
The consumables segment dominated the market in 2024, with the reagents and kits sub-segment holding over 45 % revenue share. Consumables are a necessity in workflows related to cell preparation, amplification, and sequencing, and are needed on a continuous basis for each experiment. Consumables' recurring purchase, usability, and compatibility with other platforms will maintain their overall contribution to research and clinical applications, and to their strong position in single-cell genomics products.
The software and bioinformatics tools segment is anticipated to grow at a remarkable CAGR, in conjunction with recent advances in large-scale single-cell data generation. Researchers are increasingly adopting computational platforms to analyze single-cell datasets in transcriptomics, epigenomics, and other multi-omics data. The rise of AI-based analytics, improved visualization, and cloud-based solutions is increasingly driving the usage of software-based product solutions.
Which Technology Dominates the Single-Cell Genomics Market?
The single-cell RNA sequencing (scRNA-seq) segment is the leading technology, with respect to sales in 2024, broadly adopted for its capability to capture gene expression profiles on a single-cell basis. It enables scientists to discover cell heterogeneity, characterize rarer populations, and study disease pathways with resolution. Its demonstrated application in oncology, immunology, and developmental biology continues to reinforce its dominance in the academic, clinical, and pharmaceutical research environment.
The single-cell multi-omics segment is gaining traction as the fastest-growing technology, as it combines genomic, transcriptomic, epigenomic, and proteomic data from the same cell. This provides richer biological information and accelerates the drug discovery process and biomarker identification. Growing adoption in precision medicine and advances in sequencing platforms and analytical pipelines will further drive its growth in research and clinical settings.
Which Workflow Segment is Dominating the Single-Cell Genomics Market?
In 2024, the genomic sequencing segment is projected to lead the single-cell genomics market 2024. Genomic sequencing provides high-resolution mapping of mutations, gene expression, and regulatory elements. Moreover, genomic sequencing plays a central role in elucidating disease mechanisms, especially in the fields of oncology and immunology research, firmly keeping it in the most utilized workflow category across academics, clinical studies, and pharmaceutical applications.
The data analysis and interpretation segment is expected to expand at a notable CAGR. As the diversity of multi-omics and spatial transcriptomics advances, interpretation becomes even more vital, leading to a rapid uptick in applications to follow-on workflow as independent analysis or analytical workflows that connect raw data and actionable interpretation.
Which Application Segment Dominates the Single-Cell Genomics Market?
The oncology segment dominated the single-cell genomics market in 2024, driven by the ability of the technology to study tumor heterogeneity (differences in tumor cells), the evolution of cancer in the host, and rare malignant cell populations that lead to metastasis. Single-cell genomics will aid in biomarker discovery, drug resistance evaluation, and personalized targeted treatment. This area is evolving continuously, and its application to learn about cancer diagnostics and treatment development has made it the most well-known and established application in research and clinics.
The immunology segment is expected to expand at a notable CAGR, due to the need to study the immune system complexity at the cellular level. Single-cell approaches allow for a better assessment of immune cell subsets, their interactions, and their responses to infection and therapies, which is important for understanding autoimmune disorders, creating effective vaccines, and immuno-oncology research. As the demand for immunology research increases, so will the demand for subdivisions of single-cell NNGS and single-cell proteomics, making immunology the fastest-expanding application area within this market.
Why are Academic and Research Institutes the Most Common in the Single-Cell Genomics Market?
The academic and research institutes segment accounted for the largest share of the market as it serves as a hub for fundamental research, developing new technologies, and conducting large-scale genomics projects. They have also established themselves as innovators with significant investments and growing utilization of single-cell sequencing in areas such as oncology, immunology, and developmental biology. These institutions have continually added to their leading role in advancing single-cell research and other applications due to their publications, collaborations, and government-funded developments.
The pharmaceutical and biotechnology companies segment is expected to expand at a notable CAGR. Companies within the pharmaceutical and biotechnology industry are leveraging single-cell genomics more and more for drug discovery, biomarker identification, and personalized medicine. Increasing investment in personalized therapies and immuno-oncology is heightening commercial interest and adoption, which makes this segment the most promising for market growth in the future.
Why is North America Leading the Single-Cell Genomics Market?
North America dominated the single-cell genomics market, holds the highest share of 42% in 2024, upported by significant funding for biotechnology and a strong healthcare structure. The area has a high density of top-tier academic and research institutions that contribute to the advancement and innovation of the next generation of single-cell technologies. Furthermore, the collaborations between industry and academia are helping to advance the field every day.
The U.S. is a key player in this region and helps to support the region's growth through significant public and private funding, innovation, and the development of advanced single-cell technologies. The U.S. also has numerous biotechnology companies and startups that focus solely on single-cell analysis, solidifying North America's leadership in the single-cell genomics market.
Why is Asia Pacific Projected to be the Fastest-Growing Region in Single-Cell Genomics?
Asia Pacific is on the fast track to becoming the fastest-growing region in the single-cell genomics market, propelled by more investments into healthcare and biology. Not only are the countries in the region improving their infrastructure and capacity to better accommodate the increasing demand for single-cell analysis, but the growing emphasis on precision medicine, combined with a growing number of research projects focusing on single-cell technologies, has also contributed to the rapid growth of the single-cell genomics market.
India, specifically, is a region of interest within the Asia Pacific. India is growing remarkably within the single-cell omics market due to the growing acceptance and demand for advanced genomic technologies. India is also focusing heavily on genomics research and personalized medicine, which positions it as a key player in the single-cell genomics market globally. In addition, India is home to many research care facilities and collaborations with global institutions, further indication of its global standing within the space.
Developing advanced sequencing platforms, bioinformatics tools, and reagents drives innovation in single-cell genomics. Improving sensitivity, accuracy, and data analysis capability for multiple applications is the goal of R&D.
Key Players: Bristol Myers Squibb, Thermo Fisher Scientific, Mission Bio
Reagents, kits, enzymes, and consumables provide the foundational support for experimentation. Consistent supply chains provide reliable quality for laboratories to achieve trustworthy single-cell data for genomics.
Key Players: 10x Genomics, BioLegend, QIAGEN
Biotech companies manufacture specialized sequencing instruments, microfluidics devices, and imaging tools used today. As a result, high-precision technologies can allow for the efficient isolation, amplification, and sequencing of single cells.
Key Players: Becton, Dickinson and Company (BD), Bio-Rad Laboratories, Agilent Technologies, Merck KGaA
Global distribution and logistical efficiency are essential to ensure the instruments, consumables, and reagents are delivered on time. Having a rapid logistics process will meet the rising needs of academic, clinical, and pharmaceutical research communities.
Key Players: Danaher Corporation, Mercury Shipping, NAF Pharma
By Product and Service
By Technology
By Workflow
By Application
By End User
By Region
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