Gene Delivery Technologies Market (By Delivery System: Viral Gene Delivery Systems, Non-Viral Gene Delivery System, Combined Hybrid Delivery Systems; By Application: Gene therapy, Cell therapy, Vaccines, Research; By Method: Ex Vivo, In Vivo, In Vitro) - Global Industry Analysis, Size, Share, Growth, Trends, Regional Outlook, and Forecast 2023-2032


The global gene delivery technologies market size accounted for USD 4.01 billion in 2022, and it is projected to surpass around USD 17.07 billion by 2032 with a compound annual growth rate (CAGR) of 15.59% during the forecast period 2023 and 2032.

Gene Delivery Technologies Market Size 2023 To 2032

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Key takeaways:

  • North America generated more than 42% of the revenue share in 2022.
  • Asia Pacific is expected to hold a significant share of the market in the upcoming period.
  • By delivery system, the viral gene delivery system segment is observed to hold the largest share of the market.
  • By application, the gene therapy segment has accounted for 34% revenue share in 2022.
  • By method, the ex-vivo segment dominated the market with the highest share of 43% in 2022.
  • By mode, the biological vectors segment has accounted for 59% of revenue share in 2022.

Market Overview:

The gene delivery technologies market is an industry or segment that focuses on the development, manufacturing, and commercialization of technologies or techniques used for delivering therapeutic genes. The global gene delivery technologies market offers a wide range of approaches and platforms designed to safely and effectively introduce genetic material into living organisms.

Such technologies are crucial for gene therapy. Gene therapies refer to a segment of medicinal science that deals with treating or preventing multiple diseases by silencing or modifying patients’ cells. The global market for gene delivery technologies includes numerous approaches, including various vectors, applications, and methods. At the same time, the rising understanding of molecular biology is observed to offer a bright future for the gene delivery technologies market.

Growth Factors:

The rising prevalence of chronic diseases, the accelerating pace of technological advancement, and the increasing demand for targeted therapeutics are just a few of the significant factors driving the global market for gene-delivery technologies. Advanced physical gene delivery techniques like electroporation have all seen substantial research due to advances in physics and nanotechnology. These methods are becoming more popular because of their benefits, briefness, and nontoxicity. These elements are projected to increase the demand for the products present in this market and consequently encourage operational players' organic revenue growth.

Report Scope of the Gene Delivery Technologies Market:

Report Coverage Details
Market Size in 2023 USD 4.63 Billion
Market Size by 2032 USD 17.07 Billion
Growth Rate from 2023 to 2032 CAGR of 15.59%
Largest Market North America
Base Year 2022
Forecast Period 2023 to 2032
Segments Covered By Delivery System, By Application, and By Method
Regions Covered North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa


Market Dynamics:

Driver:

Improvements in the gene delivery systems

Improvements in gene delivery systems are observed to act as a significant driver for the market. Advancements in gene delivery systems enable more effective delivery of therapeutic genes to target cells or tissues. Such improvements offer expanded treatment scope by increasing the market size for gene delivery technologies.

Moreover, the improvements in the gene delivery systems assure improved safety and increased scalability; all these factors collectively boost the adoption and commercialization of gene delivery technologies.

Restraint:

High cost of treatment

Gene therapies are widely used for treating multiple inherited disorders. The high cost of such therapies limits patients to enroll themselves for the healthcare services associated with gene therapies. Usually, the high research and production cost of therapies creates challenges for patients.

  • According to the Clinical and Economic Review, the average cost of gene therapy is $1 million to $2 million per dose/session.

The high cost of production along with the research activities affects the investments in the industry. The high cost of therapies puts a strain on healthcare budgets, especially in publicly funded healthcare systems. Governments and healthcare organizations may be hesitant to allocate substantial resources to gene delivery technologies, considering the long-term sustainability of funding such expensive treatments.

Opportunities:

Deployment of nanotechnology in gene delivery technology

Nanotechnology offers precise control over the delivery of therapeutic genes to specific cells and organs. Nanoparticles achieved by nanotechnology can be engineered to have specific surface properties that allow them to interact with target cells or organs. The deployment of nanotechnology provides stability and protection to therapeutic genes during the delivery process, which aims to improve the overall efficacy of the treatment.

In addition, the deployment of nanotechnology in gene delivery provides significant advantages in terms of combination and controlled release. With the rising efforts to bring versatility in gene delivery technologies, the penetration of nanotechnology is observed to serve multiple opportunities for market players.

Segments Insight:

Delivery System Insights:

The viral gene delivery system segment is expected to dominate the market during the forecast period. Lentiviruses, retroviruses, and adenoviruses are used as viral gene-delivery vectors. Viral gene delivery systems are made up of viruses that have been modified to be replication-deficient; these viruses were made sterile through reengineering and can deliver the genes to the cells for expression. Viral gene delivery employs lentiviruses, retroviruses, and adenoviruses.

Viral vectors are widely utilized as a gene delivery system; they use modified viruses to deliver therapeutic genes. The rising demand for efficient gene transfer and long-term gene expression will promote the segment's growth during the forecast period.

Non-viral vectors delivery system is another lucrative segment of the market that delivers therapeutics without utilizing viruses. The advantages, such as low immunogenicity, ease of production, and ability to deliver larger DNA payloads via non-viral delivery systems, support the growth of the segment.

Applications Insights:

The gene therapy segment acquired the largest revenue share of the market in 2022; the segment is expected to hold the largest share during the forecast period. The rapid adoption of gene therapies across the globe promotes the segment’s development. This segment includes applications such as treating genetic diseases, cancer gene therapy, and infectious diseases. The rising demand for precise therapeutic dosages for conditions such as cancer supports the development of the gene therapy application segment.

The research segment is another attractive segment in the market for application purposes; gene delivery technologies serve as an ideal tool for research laboratories. Researchers utilize gene delivery technologies for expression analysis, gene knockout studies, and functional genomics.

Method Insights:

The ex-vivo method segment had the largest market share in 2022; the segment will continue to grow at a significant rate. The ex-vivo method segment of the gene delivery technologies market allows the delivery of genes into cells or tissues before re-implantation into the patient.

Gene Delivery Technologies Market Share, By Method, 2022 (%)

The ex-vivo methods have been extensively used in various applications, including gene therapy and even stem cell therapy. The requirement for precise genetic modification and manipulation of cells from the industry to approach an effective treatment pattern highlights the significance of the ex-vivo method segment.

Regional Insights:

North America dominated the market in 2022, the region is expected to continue to grow during the forecast period. The massive growth of gene delivery technologies market in North America is attributed to the rapid adoption of technologies in the biotechnology and healthcare sector. The prominent academic research, the presence of multiple major biotechnology companies and the region’s overall position at research and development activities supplement the market’s growth.

The market in North America is also supported by the regulatory frameworks that facilitate clinical trials. The rising emphasis on commercializing gene therapies along with the willingness of patients to spend on gene therapies promotes the growth of the market in North America.

Gene Delivery Technologies Market Share, By Region, 2022 (%)

On the other hand, Asia Pacific is expected to witness the fastest growth during the forecast period. Countries in India, China, Japan and South Korea are witnessing rapid growth in the healthcare industry. Along with this, the rising investments in advanced gene therapies are expected to promote the growth of the market in the Asia Pacific. The rising focus on research and development activities, rising prevalence of genetic disorders and the overall advancements in the biotechnology sector contribute to the growth of the market in Asia Pacific.

The government’s support also supplements the growth of the market in Asia Pacific. The South Korean government has made significant strides in gene delivery technologies, the government is also actively promoting gene therapies along with the implementation of several healthcare policies. All these elements together fuel the growth of the gene delivery technologies market in the Asia Pacific.

Recent Developments:

  • In May 2023, a leading biotechnology company, Kytopen announced to launch a early access program for gene delivery platform. The new platform is developed to engineer cells with more efficacy and efficiency.
  • Gene Delivery Technologies Market Share, By Method, 2022 (%) Versant Venture announced the launch of a new gene delivery solution at a biopharmaceutical company Vector BioPharma AG. The company aims to employ advanced and precise gene delivery techniques that are free of viral genes.

Key Market Players:

  • Pfizer, Inc.
  • Becton, Dickinson and Company
  • Novartis AG
  • F. Hoffmann-La Roche Ltd
  • Thermo Fisher Scientific, Inc.
  • QIAGEN
  • Horizon Discovery Group Co.
  • OriGene Technologies, Inc.
  • SignaGen Laboratories
  • Bio-Rad Laboratories, Inc.

Segments Covered in the Report:

(Note*: We offer report based on sub segments as well. Kindly, let us know if you are interested)

By Mode

  • Biological
    • Adenovirus
    • Retrovirus
    • AAV
    • Lentivirus
    • Other viruses
    • Non-viral
  • Chemical
  • Physical

By Application

  • Gene therapy
  • Cell therapy
  • Vaccines
  • Research

By Method

  • Ex Vivo
  • In Vivo
  • In Vitro

By Geography

  • North America
  • Europe
  • Asia-Pacific
  • Latin America
  • Middle East and Africa

Frequently Asked Questions

What is the gene delivery technologies market size?
The global gene delivery technologies market size surpassed at USD 4.01 billion in 2022 and it is expected to increase USD 17.07 billion by 2032.
What will be the CAGR of global gene delivery technologies market?
The global gene delivery technologies market will register growth rate of 15.59% from 2023 to 2032.
Who are the prominent players operating in the gene delivery technologies market?
The major players operating in the gene delivery technologies market are Pfizer, Inc., Becton, Dickinson and Company, Novartis AG, F. Hoffmann-La Roche Ltd, Thermo Fisher Scientific, Inc., QIAGEN, Horizon Discovery Group Co., OriGene Technologies, Inc., SignaGen Laboratories, Bio-Rad Laboratories, Inc., and Others.
Which are the driving factors of the gene delivery technologies market?
The driving factors of the gene delivery technologies market are the improvements in the gene delivery systems, increasing prevalence of chronic diseases, rising need for specialized medications, and using gene expression in biotechnology.
Which region will lead the global gene delivery technologies market?
North America region will lead the global gene delivery technologies market during the forecast period 2023 to 2032.

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