Pharmaceutical Spray Drying Market Revenue to Attain USD 4.63 Bn by 2033
02 Sep 2025
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Pharmaceutical Spray Drying Market Revenue and Trends 2025 to 2033
The global pharmaceutical spray drying market revenue surpassed USD 2.56 billion in 2025 and is predicted to attain around USD 4.63 billion by 2033, growing at a CAGR of 7.68%. The market growth is attributed to the increasing demand for enhanced drug solubility, bioavailability, and stability in the development of complex and innovative therapeutic formulations.
Market Overview
The pharmaceutical spray drying market is experiencing significant growth due to several key trends. A primary driver is the increasing demand for advanced drug delivery systems that enhance the solubility, bioavailability, or stability of poorly soluble drugs. As pharmaceutical companies focus on innovative drug research, there is an increased investment in R&D, driving the development of inhalable formulations and new product formulations for vaccines and biologics. The market is also supported by growing regulatory support, a greater emphasis on continuous manufacturing, and the need for lower production costs. Additional demand drivers include the rising incidence of chronic diseases, a growing pipeline of complex therapeutics, increased regulatory agency support for novel drug formulations, and the rapidly expanding trend of outsourcing operations to CMOs.
Segment Insights
By product type, the spray-dried formulations segment led the market in 2024 due to their superior solubility, controlled release benefits, and widespread use in the development of complex drugs and biologics. They are effective in enhancing the solubility and bioavailability of poorly water-soluble drugs.
By drug type, the small molecule drugs segment dominated the market with a major share in 2024. This is primarily due to high-volume production and the need for enhanced bioavailability, particularly in chronic disease therapeutics. Spray drying is particularly effective in enhancing the solubility and bioavailability of these compounds, making it a preferred method for formulation.
By formulation type, the powder segment led the pharmaceutical spray drying market in 2024, primarily due to its stability, enhanced drug solubility, and widespread use in both inhalable and oral dosage forms.
By application, the oral drug delivery segment maintained dominance in the market in 2024 due to its patient-friendly nature, ease of administration, and widespread acceptance. Oral drug delivery ensures patient compliance and has superior solubility of drug components. The increasing demand for effective drug delivery for chronic diseases further supports segmental growth.
By operation mode, the batch mode segment led the market, holding the largest share in 2024, due to its suitability for handling small to medium-scale production, which is common during the drug development and clinical trial phases. It is highly flexible, offers precise control over processing conditions, and is widely applicable in small-scale (commercial) drug development.
By scale of operation, the commercial/industrial production segment led the pharmaceutical spray drying market in 2024, driven by the increasing number of approved drugs that require advanced formulation techniques at scale.
By end-user, the pharmaceutical companies segment held the largest share of the market in 2024 due to their high involvement in R&D, need for more accessible drug delivery platforms, and an increasing pipeline of complex therapeutics. These companies are heavily involved in drug formulation and development, driving the demand for advanced spray drying technologies.
By technique/technology used, the two-fluid nozzle spray drying segment registered dominance in the market. The segment’s dominance is supported by the versatility of the two-fluid nozzle for various formulations, affordability, accuracy in particle size, and a wide range of applications throughout drug formulation processes.
Regional Insights
North America maintained dominance in the pharmaceutical spray drying market by capturing the largest share in 2024. This is primarily due to its robust healthcare infrastructure, the presence of major pharmaceutical manufacturers, and high levels of R&D investment. The regulatory framework in North America, which supports the development of new delivery technologies, also fuels market growth. Furthermore, the rising incidence of lifestyle and chronic diseases drives demand for advanced formulations.
Asia Pacific is expected to experience the fastest growth in the coming years, driven by rapid growth in pharmaceutical manufacturing and increased healthcare investment. Countries like China and India are emerging as drug development and CMO hubs, driving local demand. The large patient population in Asia Pacific, along with the rise in chronic conditions, offers novel opportunities for innovative drug formulations.
Pharmaceutical Spray Drying Market Coverage
Report Attribute
Key Statistics
Market Revenue in 2025
USD 2.56 Billion
Market Revenue by 2033
USD 4.63 Billion
CAGR from 2025 to 2033
7.68%
Quantitative Units
Revenue in USD million/billion, Volume in units
Largest Market
Asia Pacific
Base Year
2024
Regions Covered
North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa
Recent Developments
On September 10, 2024, Evonik inaugurated a new spray-drying facility in Darmstadt for EUDRAGIT polymers, enhancing its capacity for oral drug excipients, improving supply reliability, and reducing Carbon emissions by utilizing green energy. (Source: https://www.evonik.com)
Global Pharmaceutical Spray Drying Market Key Players
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